Noah Dunham

Wild-type transaminases, a lysine smart donor, and a great scope of noncanonical amino acids, out today in @J_A_C_S (pubs.acs.org/doi/10.1021/ja…). All thanks to a crack team! @asymtmm, @RBWormwood, @RayRitwika, @yining_RPKA, @mreibarkh

@hanzyduzit Thanks Hans, couldn't have done it without your work!

Great to see that Merck has taken interest in this DKR process that we discovered a few years ago. They also expanded the reaction scope to bulkier ncAAs and products with trans (2S,3S) configuration

Lysine an amine donor in transaminase-catalyzed reactions? A thrifty hack for driving equilibria! chemrxiv.org/engage/chemrxi…

If adventure is calling, then check out my friend Prosper's new Mt. Kilimanjaro guiding company. He's an amazing guide, even got a tired crew like ours to the summit back in 2017! prosusclimbsandsafaris.com

Truly masterful talk by @Emma_Gogarnoiu on @MatthewHorwitz1's Synthesis Workshop featuring their recently published study in JACS (go.acs.org/1Yo). The chemistry is very creative, and they bolster it with a quite elegant mechanistic investigation. youtube.com/watch?v=M10DhM…

You just never know what to expect from an uninvited guest... #weddingcrasher #TRex #runforyourlife

Is this real life? 🥹

Thank you to everyone who came to my talk yesterday and for the great New Reactions & Methodology session! Looking forward to listening to some great talks this week! #ACSFall2022 #ACSChicago

Big congratulations to @dan_wise1 and @Emma_Gogarnoiu for their work on photoinduced alkene cleavage, a creative new alternative to an old reaction! pubs.acs.org/doi/10.1021/ja…

Nature’s Machinery, Repurposed: Expanding the Repertoire of Iron-Dependent Oxygenases @NoahPDunham @francesarnold ow.ly/KXcP50Cao8h

The perspective I wrote with my advisor, @francesarnold, is out today in @ACSCatalysis! We talk about native iron oxygenase mechanisms and then illustrate the abiological transformations made possible by engineering these platforms. Hope you enjoy! pubs.acs.org/doi/10.1021/ac…

Congratulations to my awesome colleague Amie Boal (science.psu.edu/chem/people/ak…) @PSUScience @BMB_PSU @psu_chemistry who was announced as the 2021 winner of the ACS Pfizer Award in Enzyme Chemistry!!! Super highly deserved!!!

A new screening technology developed by Eberly's Brad Rogers, Paul Cremer, and Tinglu Yang of @psu_chemistry works to better predict drugs' shelf life and stability — potentially reducing both time and financial costs in biological drug development. buff.ly/3bCtIWl

An Enzyme-Action-Movie, based on seven intermediate structures, is published in PNAS. Those familiar with our work should know we've gone through the distance to achieve this success (doi: 10.1073/pnas.2005327117). Congratulations to everyone who has contributed!

My latest paper in ⁦@ChemBioChem⁩ is now out. I can genuinely say that TrpB is such a fun enzyme to work with that I truly enjoyed writing this review to share my passion with the world! What can’t this enzyme do? ⁦⁦@francesarnold⁩ doi.org/10.1002/cbic.2…

Excited to share our application of Transformers to generating functional signal peptides (SPs) with @KevinKaichuang @francesarnold and a wonderful team at @basf coordinated by Michael Liszka. pubs.acs.org/doi/10.1021/ac…

So excited to announce that my student Erin McCarthy has just received the Fred Wedler Outstanding Dissertation Award @BMB_PSU, and my student Cody Lloyd just received the Paul Althouse Outstanding Teaching Assistant Award @BMB_PSU @PSUScience. Very proud of these guys!!!

@_KelvinKho @irongradstudent @KristaTooTurnt I still want to try it; it's too bad tasting the lab supplies is considered bad form.

@irongradstudent @KristaTooTurnt @NPDunham90 A nice bubbly flute of champagne chased by salty LB? 🤣

Ah, there's nothing like the smell of freshly autoclaved LB again.

Working with enzymes? Do you know what the measure 'katal' is? Find out here! Was a pleasure writing this piece @NaturePhysics. @francesarnold @CaltechCCE nature.com/articles/s4156…