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Dr. Suraj Baidya
1.2K posts

Dr. Suraj Baidya
@OPDDiaries
Doctor ⚕️ Evidence over opinion | Off duty on ucl matchdays⚽
india Katılım Mayıs 2025
235 Takip Edilen580 Takipçiler

@OPDDiaries A terrifying reminder that not every “meningitis” is bacterial or viral. Freshwater exposure + rapidly progressive meningoencephalitis should always raise suspicion for Naegleria fowleri. Early recognition is critical, though survival remains exceedingly rare.
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@Doctors_GUILD That's foramen Ovale
Structures passing are-
M:Mandibular nerve
A:Accessory meningeal artery
L: Lesser petrosal nerve
E: Emissary vein.
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@DrShauryaGarg I would be grateful if you could share your views on this case.
What are the differentials you are thinking about doc?
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@OPDDiaries No one answer
This would be very speculative.
A lot of D/D depending on lot of other missing information
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The milk was a fatal delay.
Here's the complete breakdown-
Theobromine (the toxin in chocolate) is absorbed in minutes
Milk does NOT neutralize it
By the time the dog reaches the vet, the theobromine is already in the bloodstream
Activated charcoal only works in the GI tract - it can't pull toxins already absorbed
The vet stopped because the window for charcoal had closed.
What the vet should do-
-Emesis immediately (if <2 hours)
-IV fluids to flush kidneys
-Beta-blockers for tachycardia
-Seizure control -theobromine is a CNS stimulant.
Take home message -
Call poison control immediately. Induce vomiting only if instructed. Never give milk, oil, or "home remedies" - they waste the only thing that matters: time.
Hope you liked this case. It was taken from a series called 'The Boys'.
FOLLOW to know more such interesting stories🧵
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@Doctors_GUILD He was worried about prosthetic valve endocarditis
Cause -
Before 1year - CONS
After 1 year- streptococcus viridians.
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@Madihealth2026 Yes you are absolutely correct about aspiration but there is another side of story which I will explain.
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👉Due to aspiration.
Dogs that have just been force-fed liquids (like milk) after ingesting chocolate are often nauseated and may vomit. Activated charcoal is useful for binding theobromine and caffeine from chocolate, but if the dog vomits and inhales the charcoal into its lungs, it can cause severe aspiration pneumonitis
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@thediabetes_doc D. Airway breathing circulation
ABC first then proceed from further management
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That's a classic case of HUS caused by E coli strainO157:H7
Treatment -
Management is mainly supportive:
Careful fluid and electrolyte management
Blood transfusion if severe anemia
Control hypertension
Dialysis if severe renal failure, fluid overload, hyperkalemia
Avoid antimotility drugs
Antibiotics are generally avoided in suspected Shiga toxin-associated HUS because they may increase toxin release.
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What is happening here?
>A little child suddenly gets bloody loose motions and tummy pain.
>Vomiting and weakness follow quickly.
>The child turns very pale and tired. Passes much less dark urine.
>Tiny red spots appear on the skin. Face and legs start swelling.
>Blood pressure shoots up high. Kidneys stop working and the child is not passing urine.
What is the diagnosis? How to treat this?
Kakkodi, India 🇮🇳 English

Diagnosis: Foodborne Botulism (Botulinum toxin poisoning)
The classic clue is the combination of:
-Eating canned food
-Blurred vision and diplopia (double vision)
-Dysarthria
-Dysphagia (difficulty swallowing)
-Descending, symmetrical flaccid paralysis that starts with the cranial nerves and moves downward
-Progressive respiratory muscle paralysis leading to respiratory failure.
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• Ate some homemade canned food that tasted just a little bit off
• Waking up the next day with severely blurred and double vision
• Suddenly struggling to speak clearly or swallow water
• A strange muscle weakness starting at the head and crawling downward
• Breathing becomes completely exhausting and eventually stops
What is the exact diagnosis?
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The pill bottle almost certainly contained Statins (like atorvastatin, simvastatin, or lovastatin).
👉 Grapefruit juice inhibits CYP3A4 in the gut.
This prevents normal metabolism of many drugs, especially statins.
👉 Result - toxic accumulation of the drug in the bloodstream.
👉 High statin levels can cause severe hepatotoxicity and rhabdomyolysis (muscle breakdown - kidney injury).
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@kiddiewise_ You nailed it Dr Yonni. You have explained everything related to PAM. Thank you👏
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The killer was Primary Amebic Meningoencephalitis (PAM) caused by the “brain eating amoeba” Primary Amebic Meningoencephalitis, due to Naegleria fowleri.
It enters through the nose during warm freshwater dives, races along the olfactory nerves into the brain, and causes explosive inflammation. Symptoms mimic meningitis, but death often follows within days.
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@OPDDiaries Narcolepsy but obstructive sleep apnea should be ruled out
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Answer: Naegleria fowleri — Primary Amoebic Meningoencephalitis.
The "brain-eating amoeba" entered through his nose during that dive, climbed the olfactory nerve, crosses cribriform plate and reached his brain within days. It releases enzymes that liquefy brain tissue -which is why the autopsy found a partially dissolved brain.
Why the clues matter:
Warm lake + diving = classic exposure route (enters through nose, not by drinking)
4,000 WBCs in CSF = looks exactly like bacterial meningitis
No bacteria grew = antibiotics were useless; the culprit was a protozoan, not bacteria
Rapid progression = hallmark of PAM
Liquefied brain = pathognomonic for Naegleria enzymatic destruction.
Management -
-Amphotericin B is the DOC.
-Conservative management for raised ICP.
FOLLOW for more such insights 🧵
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@NurseDan__ You nailed it. You have explained everything about PAM. The route of entry causative agent. Thank you. 👍🏻
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The 14-year-old boy died from Primary Amebic Meningoencephalitis (PAM), which is a rapidly fatal brain infection caused by the freshwater amoeba Naegleria fowleri, which enters through the nose during water activities and causes severe brain destruction that mimics bacterial meningitis but leaves bacterial and viral cultures negative
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