🧬 Rare genetic variants shed light on schizophrenia. Whole exome sequencing reveals key pathways in synaptic function, chromatin, and ubiquitin systems.
📖 Read more: oaepublish.com/articles/jtgg.…
#Genomics #Schizophrenia #JTGG
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Journal of Translational Genetics and Genomics
1.5K posts
Journal of Translational Genetics and Genomics
@OfGenomics
Official account of Journal of Translational Genetics and Genomics(JTGG). Impact factor1.0, journal #golden open access #continuous #innovative
Xi'an, Shaanxi, China Katılım Mayıs 2019
2.7K Takip Edilen508 Takipçiler
🧠 How genetics is transforming neurodevelopmental research
🔗 oaepublish.com/articles/jtgg.…
#Neurogenetics
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🆕 New Article
Maternal mosaic TUBA1A variant linked to recurrent fetal brain anomalies. Prenatal ultrasound + exome sequencing expand TUBA1A phenotypes and aid prenatal diagnosis.
📖 oaepublish.com/articles/jtgg.…
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Hot Paper Alert 🚨
Unveiling genetic diversity in Yunnan Yi & Qinghai Tibetan groups using a 41-marker Multi‑InDel panel. 🧬
High polymorphism & strong individual identification potential—valuable for forensic & population genetics studies.
🔗 Read more: oaepublish.com/articles/jtgg.…
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🔥 Hot Paper Alert: A novel SNP‑based non‑invasive prenatal paternity test shows high accuracy and lower cost — a safer approach for early detection. 🧬
🔗 oaepublish.com/articles/jtgg.…
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🔥 Hot Paper
IP3 receptors drive muscle atrophy in disuse. Blocking them preserves nuclear Ca²⁺ and ribosomal RNA, revealing a new mechanism for muscle maintenance.
📖 oaepublish.com/articles/jtgg.…
#MuscleAtrophy #IP3R
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🔥 Hot Paper Alert
Multi‑omics analysis identifies network biomarkers and repurposable drugs for Duchenne muscular dystrophy, offering new paths for diagnosis and therapy. oaepublish.com/articles/jtgg.…
#DuchenneMuscularDystrophy #DrugRepositioning
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🔥 Hot Paper! STR profiling validates human cell lines after 34+ years of cryopreservation — a key insight for long-term cell stability. 🧬
Read here 👇
oaepublish.com/articles/jtgg.…
#CellBiology #STRprofiling #Genomics
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New commentary in JTGG highlights ML- and maximum-entropy–guided AAV library design, achieving higher packaging efficiency while preserving diversity—paving the way for more effective gene therapy vectors. #GeneTherapy #AAV #MachineLearning oaepublish.com/articles/jtgg.…
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🧬 PPARGC1A rs8192678 is associated with T2DM risk and PGC-1α expression in the Chinese Han population, with a subgroup link to DKD.
🔗 oaepublish.com/articles/jtgg.…
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🔬 New article explores the role of ctDNA tumor fraction in interpreting negative liquid biopsy results.
✍️ By Gabriela Casani Cardoso & Edneia Amancio de Souza Ramos.
🔗 oaepublish.com/articles/jtgg.…
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🔬 New Article Highlight
Acquired resistance to immunotherapy in NSCLC — key mechanisms & future directions.
✍️ Commentary by Xuemei Wang, Clarivate Global Top 2% Scientist.
Read：f.oaes.cc/xmlpdf/publish…
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🔍 Long non-coding RNAs may hold the key to next-gen RNA therapies! This JTGG review from @sheffielduni breaks down mechanisms, therapeutic strategies, and hurdles toward clinical application. Must-read for RNA therapeutics researchers 👉 doi.org/10.20517/jtgg.… #lncRNA
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@NovelliGnovelli Hi Giuseppe, sorry for the ping here — just wanted to flag a DM I sent you earlier. Thanks so much!
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JTGG met with Nandita Quaderi @DrNandiQ , Vice President of @Clarivate , in Zhuhai, China, where she shared insights on editorial strategy, Web of Science content selection, and inclusion in the Journal Citation Reports.
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🔬Key highlights
🧬Novel genetic insights into disease mechanisms
💡Clear translational relevance for clinical research
🚀A step forward in human genetics and genomics
Read more 👉 oaepublish.com/articles/jtgg.…
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@NovelliGnovelli hhhh,Giuseppe, I guess you may not have seen the message I sent you😭
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Citation: Tamblin-Hopper P, Kiss-Toth E, Sudbery I, Young D, Wilkinson JM. The potential therapeutic applications of long non-coding RNAs. J Transl Genet Genom. 2024;8:225-43. dx.doi.org/10.20517/jtgg.…
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🚀 Discover how long non‑coding RNAs (lncRNAs) are reshaping the future of therapeutic strategies! 🧬
🛠️ siRNA | ASO | CRISPR tools
Next‑gen treatments
🔗 Read: oaepublish.com/articles/jtgg.…
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🔥 New in JTGG: Long Non‑Coding RNAs & Therapy
🧬 lncRNAs: key regulators in disease
💊 Therapeutic potential: siRNA, ASO, CRISPR
⚠️ Challenges: off-target effects, clinical translation
🚀 Roadmap for future RNA-based therapies
📖 Read more: oaepublish.com/articles/jtgg.…
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