Paul Breillat

The 3rd International VEXAS Workshop is coming to Milan 🇮🇹 📅 Sept 24–25, 2026 📍 San Raffaele Scientific Institute 🔔 Registration & abstract submission opening soon! Outstanding speakers on VEXAS... and beyond! Stay tuned and repost! 👀 #VEXAS #Hematology #Rheumatology

🎨Portraits En ce début de semaine, retour sur plusieurs Portraits de la Revue : (re)découvrez le portrait du Dr Paul Legendre, chef du service de Médecine Interne et d'Immunologie Clinique au CH du Mans 👇 tinyurl.com/4s4dtdat #portrait @CHLeMans

Human adenosine deaminase type 2 deficiency (#DADA2) is a rare autoinflammatory condition that results from mutations in the ADA2 gene. In this Research Letter, Isabelle Meyts @IsabelleMeyts & team @KU_Leuven report on NK cells from 11 patients with the condition, revealing an altered phenotype and functional impairment: jci.org/articles/view/…

Lupuslike manifestations associated with myelodysplastic syndromes or chronic myelomonocytic leukemia presented distinct features from idiopathic lupus, including older age, male predominance, and limited kidney or joint involvement. ja.ma/3LMmNA8

Thrilled to share the publication of my PhD work in Blood! Our study explores NK cell dysfunction in #VEXAS syndrome and its impact on severe infections. ashpublications.org/blood/article-… Grateful to my supervisor @TerrierBen and to all the collaborators who made this work possible.

On ne cesse de dire que l’histoire s’accélère, mais la géographie aussi ! « Les cartes du monde, vues de l'ISS, sont accélérées. À peine un clignement d'œil et le spectacle a déjà changé. En un battement de cil, on passe de New York à la moitié de l'Atlantique. J'avais juste le temps d'un café avant d'arriver à Paris… » (@Thom_astro)

In patients with CV-complicated Sjögren disease, only type II cryoglobulinemic vasculitis was associated with severe visceral involvement, higher risk of non-Hodgkin lymphoma, and mortality. ja.ma/3Wsv5z7

Azacitidine as therapy for VEXAS syndrome ashpublications.org/blood/article/…

In patients with CV-complicated Sjögren disease, only type II cryoglobulinemic vasculitis was associated with severe visceral involvement, higher risk of non-Hodgkin lymphoma, and mortality. ja.ma/4fkaOUU

Thrilled to share our latest publication on cutaneous vasculitis in primary Sjögren’s disease! jamanetwork.com/journals/jamad… Grateful for the invaluable collaboration with the EMSED group (Étude des Maladies Systémiques en Dermatologie) and the French ASSESS cohort.

NEW RESEARCH—Clinical manifestations, disease penetrance, and treatment in individuals with #SOCS1 (suppressor of cytokine signalling 1) insufficiency: a registry-based and population-based study bit.ly/3QKo0qx #RareDiseaseDay

Aspects cliniques diagnostiques et thérapeutiques du syndrome VEXAS academie-medecine.fr/aspects-cliniq… via @acadmed

Somatic mutations in autoinflammatory and autoimmune disease nature.com/articles/s4158…