ꙮ Pavel Janoš ꙮ

We commemorate the tragic anniversary of August 21, 1968. Nearly 30 years after Munich and 23 years after the end of the Nazi occupation, Czechoslovakia was once again invaded, its borders violently crossed by the armies of five Warsaw Pact states led by the USSR.

Most research published in Science or Nature journals are not trustable

📣 The program for #DCSB2025 is out!! We wait for you all in the beautiful city of Trieste the 18th of June! sites.google.com/view/dcsb-2025…

Just published in @NatureComms our new paper integrating #MD and #cryoEM data to construct structural ensembles of complex #RNA macromolecules 🎉✨🥳nature.com/articles/s4146…. Excellent work by @ElisaPos with @BussiGio @BonomiMax @PJanosJr N. Toor, D. Haack

We're still accepting applications for poster presentations at the CECAM conference "RNA We're still We are sill accepting applications for poster presentation at 'RNA Modelling Across Scales" conference. Apply now: cecam.org/workshop-detai… Organized with @BussiGio @devivo_marco

In Czechia beavers built a dam in 2 days, which local authorities had been planning for 7 years The animals saved the administration $1.2 million. A project to restore wetlands in the Brdy Landscape Park had been in development since 2018. Over the years, the administration gathered all the necessary permits and was ready to begin construction. But it turned out to be unnecessary—local beavers, which have lived in the park since 2020, took matters into their own hands, building dams in the required locations. "The beavers saved us 30 million Czech korunas. They built the dams without any project documentation—and for free," said the head of the nature reserve administration.

📢We are pleased to announce that the 2025 Congress of the Division of Chemistry of Biological Systems will take place in the beautiful city of Trieste! #DCSB2025 🛍️25 Fellowships for young researchers are available! 📍 18-20 June, UniTrieste Info at: sites.google.com/view/dcsb-2025…

In one year, I genetically engineered the boring Arabidopsis into a beautiful ornamental flower 🧬🌹 Here is how and why I gave this model organism a visual upgrade 🧵(1/7)

Two fully funded positions available: #PhD in Physics and Chemistry of Biological Systems @Sissaschool @SbpSissa . Deadline Aug 26, h13:00 CET. Online application: pica.cineca.it/sissa/phd-phys… Exam (remote): Sep 9-10. More info ⬇️

Some light summer time🏖️ reading: Our perspective on metalloenzyme-inspired approaches to nanozymes now out in Environ. Sci.: Nano @RoySocChem #enzyme #nanozyme #environmental #chemistry pubs.rsc.org/en/content/art…

The registration deadline of the meeting "Emerging theoretical approaches to complement single-particle cryo-electron microscopy" is today! Join us in Trieste, Italy, with an outstanding list of speakers. biophysics.org/2024trieste#/ Pls RT & Apply !

Join us in the beautiful Trieste, Italy for this event co-organized with @RommieAmaro @LanderLab, @palermo_lab & Joanna Trylska and supported by @BiophysicalSoc & @cecamEvents

@Magistrato_Lab 🚀Thrilled to share our latest research paper unveiling the mechanism of fast-cycling cancer-associated mutations in Rac1 @SmallGTPases ! 🧬👩‍🔬 Dive into the details here: onlinelibrary.wiley.com/doi/10.1002/pr… #ProteinScience #CancerResearch @AIRC_it

Two really exciting preprints that perform programmable RNA editing (!) using CRISPR-mediated trans-splicing: * RESPLICE (@pdhsu): biorxiv.org/content/10.110… * PRECISE (@jgooten @omarabudayyeh): biorxiv.org/content/10.110…

now out: doi.org/10.1016/j.ijbi… that parallel stranded d(GGGA)3GGG DNA G4 folds via multiple paths from a coil-like ensemble #moleculardynamics @sponer_lab

Interested in non coding RNAs? 🧬 Have a look at our new review @JCIM_JCTC on computing non coding RNA biogenesis and modulation. Congratulations to @silviarinaldi24, @eli_moroni, and @rrozza for their excellent work. 👏 #NoncodingRNA #compchem #compbio 👉pubs.acs.org/doi/10.1021/ac…

I am looking for a Postdoctoral Research Associate who will focus on the development of machine learning potentials for R/DNA. Ultimate goal: simulating nonenzymatic self-replication of canonical/alternative nucleic acids. Place: @ChemPWr @PWr_Wroclaw euraxess.ec.europa.eu/jobs/184618

Our #paper on the combination of force-field and ensembles refinement has been published on @JPhysChem Letters 🥳!! doi.org/10.1021/acs.jp… Congratulations Ivan Gilardoni, @TFroehlking @BussiGio. Summary 👇

📢 Still looking for a postdoc to study the role of Intrinsically Disordered Proteins in mRNA processing to start as soon as possible !! 😅 In collaboration with @rpierattelli, L. Napolitano @OnestiSilvia. Interested? Send me a CV and cover letter! pls RT.

Curious about interactions between bacterial sugars and functionalized polymeric surfaces using computer simulations? Available Ph.D. position, funded by a joint project with @cwiklik_lab under the Czech Science Foundation, at @MasarykUni. More details: charmm-gui.org/?doc=jobs&view…