Patrick Forny

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Patrick Forny

Patrick Forny

@PatrickForny

Physician-scientist in inborn errors of metabolism

St. Louis, MO, USA Katılım Mart 2014
102 Takip Edilen100 Takipçiler
Patrick Forny retweetledi
Zak Baker
Zak Baker@Zak_Bakes·
Everything you always wanted to know about the mitochondrial proteome but were too afraid to ask. From classic enzymology to novel mass spectrometry techniques. I'm so happy to finally have this out there!
Pagliarini Lab@Pagliarini_Lab

Happy to share our new mitochondrial proteome research review out today in @NatRevMCB led by @Zak_Bakes and @PatrickForny. The field has come a long way in the past 20 years, yet plenty of exciting new things to do! nature.com/articles/s4158… rdcu.be/dnmm3 #Mitochondria

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Patrick Forny retweetledi
Pagliarini Lab
Pagliarini Lab@Pagliarini_Lab·
Mitochondria need isoprenoids from the mevalonate pathway to make CoQ, but how do they access them from the cytosol? Check out our surprising finding that Hem25p doubles as an IPP transporter. #mitochondria #CoQ Hem25p is a mitochondrial IPP transporter biorxiv.org/content/10.110…
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Yue Lab at Newcastle
Yue Lab at Newcastle@TheYueLab·
A pleasure sharing my first podcast experience with former colleague now friend collaborator @FroeseLab. A decade on since we first worked on structural biology of everything #B12, this cofactor never ceases to be fun and full of surprises. @JIMD_Editors twitter.com/JIMD_Editors/s…
The Journal of Inherited Metabolic Disease@JIMD_Editors

It's #poddrop Friday with @FroeseLab and @TheYueLab The complex machinery of cobalamin (or how structural biologists stopped you eating raw liver) Apple: podcasts.apple.com/gb/podcast/jim… Spotify: open.spotify.com/episode/4Q3CoI… Soundcloud: soundcloud.com/user-109006120… @allostericstate #VitaminB12

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Patrick Forny retweetledi
Yue Lab at Newcastle
Yue Lab at Newcastle@TheYueLab·
@NCL_RareDisease @rarediseaseday @HCUAmerica @wellcometrust @APBDRF @MDBRide4Rare @MosmedC @HarringtonDI_UH @OHRareDisease @GroupBrennan 5/ Our decade-long exploration of #B12/#cobalamin proteins & disorders wouldn't have happened w/out longstanding fruitful collaboration @KispiZuerich,@FroeseLab, @PatrickForny & twitter-less Matthias Baumgartner Brian Fowler. Check out our latest review: doi.org/10.1002/jimd.1…
Yue Lab at Newcastle tweet media
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Pagliarini Lab
Pagliarini Lab@Pagliarini_Lab·
I am happy to share (a bit late) our new review on coenzyme Q biology published recently in @TrendsBiochem . Congratulations to Dr. Rachel Guerra for leading the charge! Coenzyme Q biochemistry and biosynthesis sciencedirect.com/science/articl…
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Yue Lab at Newcastle
Yue Lab at Newcastle@TheYueLab·
What a tour de force in multi-omic characterisation of #raredisease MMA patient samples to identify novel #metabolomic signature, protein interactors & diagnostic features, from our collaborators @FroeseLab @PatrickForny et al from @KispiZuerich. Many congrats!
Patrick Forny@PatrickForny

Our new article is out today in @NatMetabolism ! Years in the works we deciphered a cohort of 210 rare metabolic disease patients by #multiomics. Grateful to the whole team at @KispiZuerich @PHRT_CH @ETH_en @UZH_en @FroeseLab ! nature.com/articles/s4225…

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Patrick Forny
Patrick Forny@PatrickForny·
As a regulatory model we propose physical interactions between MMUT and other anaplerotic enzymes (as evidenced by affinity purification-mass spectrometry).
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