Peter Siska

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🚨 Exciting data at #ESMO25! @katy_beckermann presented the Kidney Cancer Research Consortium trial: 👉 Phase 1b/2 study of ipi + nivo + ciforadenant (A2A R antagonist) in 1L ccRCC Immunometabolism meets IO in kidney cancer. 💥 #RCC #ImmunoOncology #ESMO2025

💡 OPTIC RCC: precision oncology in action! Using RNA-seq cluster biology to enrich for response in frontline #RCC. 🔹 76% ORR in angiogenic clusters with nivo+cabo 🔹 Ipi+nivo enrolling immune clusters next Next steps ➡️ expand IO arm & move toward liquid biopsy to replace invasive mets bx. So proud to contribute to this meaningful work with an incredible team @brian_rini @DrScottHaake 🙌 Huge thanks to Vindyha Data Science & Tempus— proof it can be done! 💪 #ESMO25 #KidneyCancer #TranslationalResearch #PrecisionOncology

Wonderful seeing you again, Katy! Hard to believe how far things have come since our Rathmell*2 lab days — and how much progress we’ve seen in RCC therapies since then. Always a pleasure to catch up!! #KidneyCancer #Immunometabolism #GU25

Great thanks to the Working Group Medical Oncology (@AIO_Onkologie) for the scholarship! See you at #ESMO25

I am deeply shocked by the news of the cowardly attack on Slovakian Prime Minister Fico. Violence must not be existant in European politics. In these hours, my thoughts are with Robert Fico, his family and the citizens of Slovakia.

Dr @Oferman1 cancer #mmunotherapy guru @HebrewU SPECTACULAR TALK! reviews the nectin family of receptors and describes new anti-PVR AB that restores DNAM1 activity and T cell/NK cell function/Clinical trial has started at 5 sites. 22 patients doses. @sitcancer #TIMO2024

A brand new paper from @MarinaKreutz lab showing what Hydroxyglutarate does to the immunogenicity&metabolism of myeloid and AML cells! Possible combinations of anti-glycolytic drugs and epigenetic modulators for AML in the future? 💊🩸 haematologica.org/haematologica/… @Haematologica

Congrats Kim !!!

BREAKING: @POTUS announced his intention to appoint internationally recognized kidney cancer expert, Dr. W. Kimryn Rathmell, as the 17th Director of NCI. spr.ly/6019u2hWW

New #JITC article: MCT4 blockade increases the efficacy of immune checkpoint blockade bit.ly/3tLGqiL @BablNathalie @MarinaKreutz

@ApostolovaPetya @JEdwardsHicks @NatImmunol nice work, congrats!!

Excited&proud to share our work on lipid metabolism in CD8 T cells, with co-first author @JEdwardsHicks from the Erika Pearce lab, out today in @NatImmunol !! Phosphoinositide acyl chain saturation drives CD8+ effector T cell signaling and function nature.com/articles/s4159… 🧵⬇️

It was a great honor to present at the JSIC7 as a keynote speaker! Thanks to Wolf Hervé Fridman and Eric Tartour for this opportunity and to the whole organizational team for great work! #Immunotherapy #CancerResearch #metabolism

How are CD8 T cells in human tumors epigenetically "ticking"? Happy to share a new paper @MolecularCell where we collaborated with Chris Schmidl and his team to get new insights on TIL from kidney cancer and other tumors!

Got a chance to listen to excellent talks @KeystoneSymp #Immunometabolism and also to give a talk about our work in #COVID19 Immunometabolism! Btw, altitude sickness + jet lag is a weird combination :)

Our editor @DrTimPImmuno is attending the #ImmunoMetabolism @KeystoneSymp in Keystone Colorado. Reach out to him to learn more about @NatureComms or to discuss potential submissions in the field of immunology and immunometabolism. keysym.us/22J1Nature

Medizinische Hilfe für die Ukraine gofund.me/6b3d512b

One of the most extraordinary videos I’ve ever seen. The first woman is holding up a sign that says ‘two words’.

n=2 -> Nature? I beautiful paper with cutting-edge technologies, a ton of data, and a hot topic. But still, n=2.. come on :) nature.com/articles/s4158…

Explain to a patient risk and benefit of a stem cell transplant...#bmtsm