Peter Chen

Efficient prime editing in two-cell mouse embryos using PEmbryo go.nature.com/483v6g9

@Fatwa_Adikusuma My apologies! We originally discussed your embryo data in the PE-nuclease section, but removed it for space.

@PeterJ_Chen By the way, I noticed you didn't discuss our paper when discussing prime editing for mouse embryo generation. Our study showed very efficient prime editing in mouse zygote injections using PE-nuc.

Excited to share our review on prime genome editing! Enormous thank you to everyone who has developed and innovated this technology!

@doyonlab Although we were allowed to, we couldn’t cite many preprints because we were asked to stay under 150 total citations!

@PeterJ_Chen Thanks Peter for mentioning our work. Highly appreciated! Out of curiosity, would have they allowed citations of preprints? Thanks

Today we share in @NatureRevGenet a review of prime editing for precise and versatile genome manipulation. The review covers current prime editing strategies, limitations, recent developments, and applications, including work from 148 publications. 1/5 drive.google.com/file/d/1K4emjR…

Today we share in @NatureProtocols detailed strategy and experimental procedures for designing and executing prime editing (and twinPE) experiments in mammalian cells. Congrats Jordan, @AlexanderASousa, Peyton, and @PeterJ_Chen for this thorough analysis. drive.google.com/file/d/12oIqq5…

In the latest issue! PE4 and PE5 are efficient and precise prime editing systems with enhanced efficiency of substitution, small insertion, and small deletion prime edits #geneediting #primeediting #sciencetwitter @davidrliu @Harvard @broadinstitute bit.ly/2ZsB5gX

Our work developing Repair-seq, a platform for studying #DNArepair processes, and its application to double-strand breaks is out today @CellCellPress. Alongside, we release seq.repair, a portal for exploring many, many DNA repair phenotypes! cell.com/cell/fulltext/…

Today we report in @CellCellPress our new PE4max and PE5max prime editing systems that we first presented at @CSHLmeetings in August. 1/12 drive.google.com/file/d/1IGiVl7…