Polio

5.2K posts

Polio

Polio

@Polio2022

Engineering, AI, Environment, Covid Awareness

Katılım Ağustos 2022
3.5K Takip Edilen1.8K Takipçiler
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Polio
Polio@Polio2022·
👋Hi, I’ve been away for a very long time. Wondering if you could introduce me to a few friends?
Monkeypox@mildmonkeypox

@friendlycovid19 Nice to meet you. I'm new to the pandemic party 🥳

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Harry Spoelstra
Harry Spoelstra@HarrySpoelstra·
Tissue-specific autoantibody signatures reveal immune alterations undetected by routine serology in long COVID 🚨83% of long COVID patients have rogue autoantibodies attacking their own heart, lungs & blood vessels, and every standard blood test misses it completely. VERY INTERESTING! ➡️In a UNIQUE Hungarian cohort of 114 long COVID patients versus 36 pre-pandemic controls, tissue-specific Western blotting detected autoantibodies in 83% of cases, with strong cardiovascular dominance, ➡️Vascular autoreactivity was markedly higher in long COVID (34% vs. 8%, p<0.05), cardiac (54%) and pulmonary (34%) signals trended elevated but did not reach significance( cohort size?), ➡️Autoantibodies were predominantly IgM-skewed, polyreactive (up to 8 bands per patient), and persisted longitudinally (mean 141 days), with new isotypes emerging over time, ➡️Standard ANA testing showed no group differences and zero clinical correlations, rendering it useless for detecting these alterations, ➡️Cardiac autoreactivity associated with hypertension and headache, overall autoreactivity correlated with anosmia/ageusia, female sex, CRP, BMI, creatinine, and troponin levels, ➡️The study used human cardiac, pulmonary, and vascular tissue homogenates. ➡️Findings were independent of routine serology and highlight an under-recognized immune component invisible to current diagnostics. ➡️“This persistent, IgM-skewed profile suggests ongoing immune dysregulation and may reflect a previously underrecognized component of the immunological response in long COVID, highlighting the need for targeted immunodiagnostic approaches beyond routine serology.” ‼️Why this is shocking: It proves that in 83% of long COVID patients, the immune system is actively producing autoantibodies that directly target their own heart, lung, and especially blood-vessel tissues, yet every standard blood test (ANA HEp-2) comes back normal. These rogue antibodies are polyreactive, IgM-dominant, persist for months, and keep evolving. They correlate with real symptoms (anosmia, hypertension, headache) and lab markers of damage (troponin, CRP). ‼️In other words: The majority of long COVID sufferers have smouldering, organ-specific autoimmunity that is completely invisible to routine diagnostics. Doctors are flying blind while patients’ tissues are quietly under autoimmune attack. 🤔As far as I know, this is the first direct evidence of hidden, cardiovascular-dominant tissue autoimmunity driving the chronic L0ngC0vid phase! #BookMark #AvoidSars2 #AvoidReinfections link.springer.com/article/10.100…
Harry Spoelstra tweet media
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Froglet 🐸
Froglet 🐸@froglet80·
@Polio2022 That's good to know, thank you for this. Can you point me towards them?
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Meghan McCain
Meghan McCain@MeghanMcCain·
Can someone who is an expert in this space just keep it real with me and tell me if I should be worried about Hantavirus or not? I've got 3 kids and the youngest is 4 months old, I don't know what to believe.
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Polio
Polio@Polio2022·
@TriciaDearborn Just imagine, 30 years from now, after the grammar checkers have influenced how people talk and everyone speaks like a pirate. Arrr 🏴‍☠️
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Tricia Dearborn
Tricia Dearborn@TriciaDearborn·
Word's grammar check has just suggested that I change "3000 kilometres is a long way" to "3000 kilometres *are* a long way". Which is one of the reasons I ignore the grammar check.
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Eric Feigl-Ding
Eric Feigl-Ding@DrEricDing·
Wow, if true— it means Trump’s CDC is wrong/lying about “prolonged close contact” needed for hantavirus transmission. The cruise ship 🛳️ doctor tells @j_g_allen that 3 positive ship cases did not have any close contact — only shared spaces—this implies AIRBORNE TRANSMISSION.
Eric Feigl-Ding tweet media
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Sovey
Sovey@SoveyX·
I officially reached the end of the Internet. Don’t ask me what I searched to find this.
Sovey tweet media
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Polio
Polio@Polio2022·
@Kenneth33071904 Now why would the US let this turn into a pandemic. What would it be a very convenient distraction from?
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Pessimistic Persimmon
Pessimistic Persimmon@Kenneth33071904·
I can’t handle another pandemic. It’s so inconvenient for me. I already do my part spreading Covid around. I can’t handle another one.
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Polio
Polio@Polio2022·
@LauraMiers Some people blow whichever way the wind is blowing, with no real moral or scientific compass. I wouldn’t be surprised if they suddenly start taking maskless photos on cruise ships.
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Laura Miers
Laura Miers@LauraMiers·
There’s an epidemiologist on here who I used to come for all the time because he wrote a nasty anti-masking op-ed in the middle of 2021 & was a hardcore Covid minimzer for over 5 years. Well anyway, he’s taking hantavirus SO SERIOUSLY, it’s actually really unsettling.
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matt
matt@mattxiv·
“it’s a virus, i get it, i respect it” really did change my brain forever
@buffys

hantavirus

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Emma Hilton
Emma Hilton@FondOfBeetles·
On Hantavirus: a (non-technical) thread. Disclaimer: I am a biology PhD, but not virology/epidemiology. Husbandman is a virology PhD. But I’m told I’m good at communicating science, so here’s my take. #Hantavirus
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Polio
Polio@Polio2022·
@1goodtern The best part, they always spend 10 plus minutes checking your insurance before they will treat you. Is your eyeball hanging outside your face? “Sorry, but can you please fish around in your pants pockets for your insurance card.”
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Polio
Polio@Polio2022·
@1goodtern You can go to an in network hospital, do all your due diligence, but a random doctor isn’t “in network.” You find out weeks and months later when bills start showing up in the mail. Medical bills are the number 1 reason for bankruptcy in the US.
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