Matthias D'hooghe

Two weeks ago, Alexandre Bringuet – a Master student @ChimieParisTech – joined our team for a five-month internship. He will study CO2 capture reactions for the construction of new azaheterocycles, supervised by our PhD student Fien Vanhecke. Welcome Alexandre! @SynBioC @FbwUGent

#ChemistryOpen A Convenient Laboratory-Scale Synthesis Route Toward the PPARα Agonist Pemafibrate (Matthias D'hooghe and co-workers) @prof_mdhooghe #OpenAccess doi.org/10.1002/open.2…

Last week, our PhD student Maya Boone presented her work on the preparation of curcuminoid-lanthanide complexes at the 15th Inorganic and Bioinorganic Chemistry Conference in Lisbon 🙂, @SynBioC, @FbwUGent, #curcumin

The EU plans to ban the CF₃ group in 2026–2028. Here is the alternative: bit.ly/4tgOLUW

Need Pemafibrate? Check out our new route to this PPARα agonist, allowing for the efficient and low-cost preparation of enantiopure Pema at the multigram scale – developed by our PhD student Felien Morlion: dx.doi.org/10.1002/open.2…. @SynBioC @VIB_CMB @FbwUGent @crighent

Bekijk hier de reportage: sporza.be/nl/2026/02/12/…

We are extremely glad to organise the Catalytic CO2 Conversion conference (CCC 2026) on 25 - 28 th of August, 2026 in Copenhagen. We are very much looking forward to see many of you in Copenhagen in August. Please stay tune with us for further updates! ccc2026.org/index.html

Our biology paper on curcumin-based benzothiazepane analogs with selective anticancer activity in HCT-116 cells (Prof. Van Camp lab) is now published in Biomedicine & Pharmacotherapy: sciencedirect.com/science/articl… @SynBioC @FbwUGent @Sciencedirect

Our @SynBioC PhD student Ulrike Ronse presenting our work related to HDAC6 inhibitor development at the MedChem 2025 meeting in Ghent (Dec. 15th) 😀 @VIB_CMB @FbwUGent @crighent

New publication!! 🥳🎉👏🏻🙌🏻🔝Take a look to our chapter about the application of the Prins reaction in the synthesis of six-membered oxacycles doi.org/10.1016/bs.aih…

@Va_le_nti_ @SynBioC @FbwUGent @sciencedirect It seemed interesting to us to explore lanthanide materials which have the same applications as Ln phosponate coordination polymers but are more easily synthesized. Furthermore, the combination of nanomaterials with nucleotides is promising because of water compatibility.

@prof_mdhooghe @SynBioC @FbwUGent @sciencedirect Impressive work! Lanthanides always fascinated me, what inspired you to dive into nucleotide coordination polymers for sensing?

New paper alert 📢 Our review article on lanthanide nucleotide coordination polymers for sensing applications is published in Coordination Chemistry Reviews: doi.org/10.1016/j.ccr.… @SynBioC @FbwUGent @sciencedirect

Happy to share our publication dealing with the targeted #HDAC degradation via direct DDB1 recruitment. Congrats to first author Shiyang @Vincent_SYZ and everybody involved. Great collaboration with the Geyer lab @Geyer_lab! #BonnTPD pubs.acs.org/doi/10.1021/ac…

While a spoonful of sugar helps the medicine go down, glycosylated PROTACs are a nifty way to metabolically control PROTAC activity 🤩🟦🍬 Check out our newest work out now is @J_A_C_S 🫡 Congrats to Chace and all authors! 💐🎉🐱 pubs.acs.org/doi/full/10.10…

Our former @SynBioC postdoc Goran Poje presenting his research on harmine-curcuminoid hybrids at the EFMC-ASMC 2025 conference in Porto😀@FbwUGent @EuroMedChem

Our @SynBioC PhD student Kato Bredael presenting her research on monocyclic β-lactam antibacterials at the EFMC-ASMC 2025 conference in Porto😀@FbwUGent @FWOVlaanderen @EuroMedChem

Our review paper on the synthesis and antibacterial properties of C4-functionalized β-lactams is published in @ChemMedChem: doi.org/10.1002/cmdc.2… @SynBioC @FbwUGent @emmavandenheede @CStevens_UGent

Our PhD student Ulrike Ronse presenting a decade of work on HDAC6 in our group at the Medicinal Chemistry Frontiers 2025 conference in Chicago 😀 @SynBioC @VIB_CMB @FbwUGent @EuroMedChem

Check out our new paper on 3-imino-β-lactam chemistry, published in @JOC_OL: pubs.acs.org/doi/full/10.10… @SynBioC @CStevens_UGent @emmavandenheede @FbwUGent

Re-inventing the wheel. Instead of a #ChemEd #Chemistry summary, here is my attempt at a pKa (in H2O) scale. Values are taken from the Evans/Ripin & Hans Reich resources. If you want a table, I recommend these. This was an attempt at a more visual representation of the same data.