Woo Lab

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Woo Lab

Woo Lab

@thewoolab

Official Account for Christina Woo’s Lab @HarvardCCB | chembio, protein mods, chemoproteomics, TPD | Student-run account | tweets by Christina signed CMW

Cambridge, MA Katılım Nisan 2015
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Woo Lab
Woo Lab@thewoolab·
The Woo Lab is officially on BlueSky 🦋! Give us a follow @thewoolab.bsky.social ~~ and don’t worry, we won’t be abandoning this app, just expanding our horizons 🩵💙
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Woo Lab
Woo Lab@thewoolab·
Excited to share our pub in @acsbiol, a collaboration with our colleagues across the pond at @dundeeuni 🏴󠁧󠁢󠁳󠁣󠁴󠁿 ! We show how protein complexes affect the TPD when degrading targets like CK1α. Congrats Nicole and our collaborators in the Sapkota lab! 🌟🍇💙pubs.acs.org/doi/10.1021/ac…
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Zeba Rizvi
Zeba Rizvi@Zebra_Cullin·
Grateful to @AmericanCancer Many thanks to my mentors @LanderLab @thewoolab and GabeS for working on this together, to @Wardlab1 for letting me continue this project. 👏🏽 @sijwali_puran @Sankar_Lab for providing references. Lindsey from @scrippsresearch for highlighting this ♥️🎉
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Scripps Research@scrippsresearch

Congrats to Zeba Rizvi (@Zebra_Cullin), a postdoctoral researcher in the @WardLab1, on receiving an @AmericanCancer Society Postdoctoral Fellowship for her work on cereblon (CRBN), a key cancer drug target—building on research initiated in the @LanderLab. More: ow.ly/itp550YHhMt

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Woo Lab
Woo Lab@thewoolab·
A little throwback for you on this beautiful Thursday—Alison's article on her proximity-induced O-GlcNAcylation paper from last December is out now in @NatRevMCB! 🍭🟦🌟💙#glycotime doi.org/10.1038/s41580…
Woo Lab@thewoolab

Let us take you to the land of sweets with our latest work in @CellChemBiol! Excited to share this proximity-induced target O-GlcNAc approach, where we uncover transcriptional effects of O-GlcNAc. Congrats to Alison and Dan! 🟦🍭🍬🎵❄️ sciencedirect.com/science/articl…

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Woo Lab
Woo Lab@thewoolab·
Roses are red, GlcNAc is blue, sugar is sweet, and we want YOU to read our latest in @NatureComms — where we identify small-molecules that disrupt OGlcNAc homeostasis via RNA splicing. Congrats Steven (@scheng23) and all the authors! 🟦🍭❤️ nature.com/articles/s4146…
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Woo Lab
Woo Lab@thewoolab·
Another Woo Lab Dr. is in: Congrats to our newest Ph.D, Dr. Alison Mody!🫡 Cheers to a wonderful Ph.D. and a sweet (pun intended) thesis talk, all the world’s alpacas are celebrating with you in spirit 🦙🩵🟦💐🎉
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Woo Lab
Woo Lab@thewoolab·
we hope you enjoyed this paper as much as we do! 😉😘 if you’re interested in working with an allosteric ligand, reach out to Prof. Woo 🫡 we’re more than happy to share 🙌🏼🩵✨ #thefutureisallostery #CRBN #TPD
Woo Lab@thewoolab

Pour a glass of champagne AND red Bordeaux—Our newest work with @GSK and @scrippsresearch is out in @Nature, where we describe SB-405483, the first allosteric CRBN ligand which potentiates neosubstrate degradation. Congrats Vanessa and all authors! 🍷💫💐 nature.com/articles/s4158…

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Woo Lab
Woo Lab@thewoolab·
@Zhenguang4 🫶🏼🫶🏼 miss you already, Prof. Zhao 😉 Looking forward to the science your lab will produce 🫡
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Zhen-guang
Zhen-guang@Zhenguang4·
It is a really amazing journey in Woo Lab at Harvard! It is a sad time to say goodbye, but also a exciting time to start a new journey in China Pharmaceutical University! Good luck to everyone in Woo Lab and in coming Zhenguang' Lab!
Woo Lab@thewoolab

He’s gonna be gonna be golden! ⭐️ While we’re sad that our beloved postdoc, Dr. Zhenguang Zhao, is leaving, we’re excited for his next steps as he becomes Prof. Zhao at China Pharmaceutical University! 🤩✨🌟

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Xavier Tao
Xavier Tao@XavierBTao·
Happy to see this work on the first allosteric cereblon (CRBN) ligand out! E3 ligase allostery holds great promise for modulating targeted protein degradation. Huge thank you to all the collaborators for making this research possible!
Woo Lab@thewoolab

Pour a glass of champagne AND red Bordeaux—Our newest work with @GSK and @scrippsresearch is out in @Nature, where we describe SB-405483, the first allosteric CRBN ligand which potentiates neosubstrate degradation. Congrats Vanessa and all authors! 🍷💫💐 nature.com/articles/s4158…

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Woo Lab
Woo Lab@thewoolab·
While allostery is biochemical cooperation, this was an epitome of scientific collaboration💙. We'd like to thank our collaborators at GSK and the Lander Lab at Scripps, without whom this work would not have been possible 💙💐🤝
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Woo Lab
Woo Lab@thewoolab·
Pour a glass of champagne AND red Bordeaux—Our newest work with @GSK and @scrippsresearch is out in @Nature, where we describe SB-405483, the first allosteric CRBN ligand which potentiates neosubstrate degradation. Congrats Vanessa and all authors! 🍷💫💐 nature.com/articles/s4158…
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Woo Lab
Woo Lab@thewoolab·
He’s gonna be gonna be golden! ⭐️ While we’re sad that our beloved postdoc, Dr. Zhenguang Zhao, is leaving, we’re excited for his next steps as he becomes Prof. Zhao at China Pharmaceutical University! 🤩✨🌟
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Woo Lab
Woo Lab@thewoolab·
This work is a proud collaboration with our colleagues in the labs of Ning Zheng (@nzhenguw, UW 🐺) and Manuel Guzman (UCM 🇪🇸)🫡
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Woo Lab
Woo Lab@thewoolab·
We’re popping the champagne prior to New Year’s because our work on how PCMT1 enzymatically forms the CRBN degron is officially out in @nchembio 🥂!! Congrats to Zhenguang (@Zhenguang4), Wenqing, Ethan (@EthanYFeng), Shiyun, and all the authors! 🎉💜🍾 nature.com/articles/s4158…
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Woo Lab
Woo Lab@thewoolab·
Happy holidays from our lab family to yours! 🎁🎄Wishing everyone warmth, cheer, and light this season ❤️
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Woo Lab
Woo Lab@thewoolab·
Biggest congratulations to our newest Ph.D., our protein biochemist extraordinaire, Dr. Hannah Lloyd! We will miss you and your baked goodies 🍰 🍪, but we know you’ll off to brilliant things in the Baskin Lab at @CornellChem! 🎉 💜 💐 🍰
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Woo Lab
Woo Lab@thewoolab·
Let us take you to the land of sweets with our latest work in @CellChemBiol! Excited to share this proximity-induced target O-GlcNAc approach, where we uncover transcriptional effects of O-GlcNAc. Congrats to Alison and Dan! 🟦🍭🍬🎵❄️ sciencedirect.com/science/articl…
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