Pyr Brain Game

The Institute for Advanced Study (@the_IAS), the fabled home of Einstein and Gödel, announces a 2026-27 program on Modeling Fly Vision, intended to refound theor/comp neuro on the bedrock of 21st century brain maps. Apply for membership! #special-year" target="_blank" rel="nofollow noopener">ias.edu/sns/csb#specia…

New preprint alert: hippocampus CA3! ∼1×1×0.1mm3 volume with 1,815 pyramidal neurons, 229 inhibitory cells, and 55,000 mossy fibers (like the ones shown below). Access the data at pyr.ai and explore the preprint below

A quick guide to 3D neuron navigation in neuroglancer: youtu.be/4Pi0QpjkDcI (try saying that 3 times fast) Explore interactive neurons from the microns dataset: microns-explorer.org/gallery-mm3

Venture into the hippocampus: pyr.ai

a little Picasso hidden in the dataset #em found by citizen scientist Krzysztof Kruk pyr.ai

mossy fiber with several long filopodia request early access to Pyr CA3 dataset to unlock interactive 3D: play.pyr.ai/#!middleauth+h… pyr.ai/ca3_access

A spiraling dance of neural threads, twisting, branching, in the head. A tangle born of thought and time, synapses spark and neurons climb. In crimson rivers, pathways stream, etching maps of hidden dreams. Image from CA3 by Nseraf

>1,000 axons presynaptic to CA3 spiny pyramidal neurons have been proofread by citizen scientists. pyr.ai

A few presynaptic axons connecting to a CA3 pyramidal neuron. Request early dataset access here: pyr.ai

Request early access to a new Hippocampal Formation CA3 dataset -> pyr.ai

Coming soon: Hippocampal CA3 dataset

inhibitory axon of the hippocampus

🔥⚡ Action Potential: When neurons gossip ⚡🔥 "Hey, did you hear? Na+ rushed in, K+ stormed out, and BAM 💥 signal sent!" Sparking thoughts, moves, and feels. science.eyewire.org/neurons

Wishing you a dazzling holiday season! Explore an interactive 3D pyramidal neuron from deep in visual cortex: microns-explorer.org/mm3/layer5_thi… @AllenInstitute @IARPAnews @PrincetonNeuro

Connectomics brings the brain into focus. Explore data from IARPA microns: microns-explorer.org

Vampyramidal neurons. Happy Halloween! #neuroscience

If you are good at programming / data analysis / algorithms and like challenges read on! FlyWire is issuing its first Data Challenge. We'll fly the winner to Princeton to give a talk about their solution🧵

One huge neuron! Layer 5 excitatory pyramidal

My latest #neuro #visualization: An intuition pump on connectivity in the #brain ~75K #neurons in the #MICrONS mm³. I/O segregated by layers, function is columnar; the cortical column is the unit of cortical computation. A typical #pyramidal cell has over >10K input #synapses.

We’ve got holiday cheer on the brain. Happy holidays from your friends at Pyr