Mach Lab

19 posts

Mach Lab

@RHMachLab

Laboratory of Robert H Mach

University of Pennsylvania Katılım Nisan 2020

36 Takip Edilen64 Takipçiler

Mach Lab@RHMachLab·28 Şub

Exciting work from our lab on computer-aided drug design for radio-tracer development titled “Computational Chemistry for the Identification of Lead Compounds for Radiotracer Development” has been recently published in Pharmaceuticals mdpi.com/1424-8247/16/2…

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Mach Lab@RHMachLab·20 Kas

Mach lab and friends at the ⁦@UofPenn game! ⁦@aladdinBro @TaraTaghvaee @GuilongT⁩ @ChemistryGrEEK @rickbarrett_phd @air_sea_sam⁩

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Mach Lab retweetledi

The Science of Parkinson's@ScienceofPD·6 Tem

Poly (ADP-ribose) (PAR) is reported to interact with phosphorylated α-Synuclein in post mortem #Parkinsons samples - from @RHMachLab & colleagues; Interactions between negatively charged PAR & lysine residues on the N-terminal region of αSyn confirmed frontiersin.org/articles/10.33…

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Mach Lab@RHMachLab·26 May

@Scott_LabUM @SocRadiophSci Thank you @Scott_LabUM it was a great conference with a lot of exciting research!

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ScottLab@Scott_LabUM·17 May

And we're off with the latest developments in #TotalBodyPET from Bob Mach #eSRS #SRS @SocRadiophSci @RHMachLab

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The Science of Parkinson's@ScienceofPD·1 Nis

New evaluation of a low-toxicity PARP inhibitors as a neuroprotective agents for #Parkinsons from @RHMachLab; The ideal PARP inhibitor needs to inhibit PARP-1 hyperactivity while also limiting downstream DNA damage & cellular toxicity (ideal for oncology) link.springer.com/article/10.100…

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ScottLab@Scott_LabUM·19 Şub

Just realized our friends from @RHMachLab at @PennRadiology are on the Twitter! Show them some love!

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Penn Medicine CSO@PennMedCSO·1 Eki

Proof-of-concept study demonstrates new approach for identifying #PET tracers for Parkinson’s & other neurodegenerative diseases🧠 ft Virginia Lee (@PennPathLabMed), @RHMachLab, Zsofia Lengyel-Zhand (@PennRadiology), @EJPLab & John Ferrie (@PennChemistry) bit.ly/33MngIT

GIF

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Bieneke Janssen@BienekeJanssen·11 Ağu

Our review @RHMachLab @WindhorstBert featured by @Molecules_MDPI !

Molecules MDPI@Molecules_MDPI

#HighlyCitedPaper #HighlyAccessedPaper PET Imaging of Microglial Activation—Beyond Targeting TSPO By Robert H. Mach, et al. 👉mdpi.com/1420-3049/23/3… #positronemissiontomography #microglia #neuroinflammation

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Bieneke Janssen@BienekeJanssen·26 Şub

Check out our recently accepted manuscript 📝 in @ChemCommun Synthesis and Characterization of High Affinity Fluorogenic α-Synuclein Probes 🔗 pubs.rsc.org/en/content/art…

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bioRxiv@biorxivpreprint·20 Şub

The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor complex are responsible for the cellular uptake of Aβ42 and its protein aggregates biorxiv.org/cgi/content/sh… #bioRxiv

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bioRxiv Neuroscience@biorxiv_neursci·20 Şub

The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor complex are responsible for the cellular uptake of Aβ42 and its protein aggregates biorxiv.org/cgi/content/sh… #biorxiv_neursci

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Mach Lab@RHMachLab·24 Nis

PARP-1 tracer demonstrates that PARP-1 expression is independent of breast cancer subtype providing foundational evidence to test PARP PET as a companion diagnostic for PARP inhibitor therapy jamanetwork.altmetric.com/details/799318…

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Mach Lab@RHMachLab·24 Nis

RT @PennRadiology PARP-1 tracer demonstrates that PARP-1 expression is independent of breast cancer subtype providing foundational evidence to test PARP PET as a companion diagnostic for PARP inhibitor therapy jamanetwork.altmetric.com/details/799318…

Penn Radiology@PennRadiology

Great @PennMedicine team effort on clinical trial shows PARP-1 expression is independent of breast cancer subtype providing foundational evidence to test PARP PET as a companion diagnostic for PARP inhibitor therapy jamanetwork.com/journals/jamao… #PARP1 #breastcancer @PennMDForum

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Penn Radiology@PennRadiology·16 Nis

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Keşfet

@UofPenn @AladdinBro @GuilongT @ChemistryGrEEK @RickBarrett_PhD @air_sea_sam @Scott_LabUM @SocRadiophSci