Penn Path & Lab Medicine retweetledi
CAR T cell therapy leads to 10-year remissions in B-cell lymphoma patients ft. @carlhjune (@PennPathLabMed), Stephen Schuster & @MarcoRuella (@PennCancer) tinyurl.com/339p3tnu
English
Penn Path & Lab Medicine
5.4K posts
Penn Path & Lab Medicine
@PennPathLabMed
Pathology and Laboratory Medicine @Penn: AP, CP, Research, Transfusion Medicine & Therapeutic Pathology, and Precision Dx
Philadelphia, PA Katılım Şubat 2014
930 Takip Edilen3.3K Takipçiler
Looking for another interesting and informative podcast? @TNRLab Eddie Lee, MD, PhD, was recently featured on the Age of Aging podcast🎙️ to discuss the effects of long-term exposure to air pollution on the brain.
Listen to the episode here 🔬: podcasts.apple.com/us/podcast/pol…
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A great new paper was published in @JAMA_current by PLM's @TNRLab Eddie Lee, MD, PhD, on the promising impact of amyloid plaque removal on Alzheimer's disease. Awesome work being done by the team and Penn Memory Center.
Read the paper🔬: jamanetwork.com/journals/jama/…
Penn Medicine@PennMedicine
A new analysis by @PennPathLabMed found that clearing amyloid plaques from the brain may have long-term effects on the biological processes that drive Alzheimer’s disease. spr.ly/6014BEnoQC
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🎉 Congratulations to @YeqiaoZhou on the award of an NCI K99 Grant!
We are constantly amazed by the talent on our team.
R. Babak Faryabi@bfariabi
I am delighted to share that @YeqiaoZhou from our lab was awarded an NCI K99 grant! Her application scored in the 3% on its first submission- an outstanding achievement. @PennPathLabMed @PennEpiInst @pennbgs
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Congratulations to Daniel Akuma, MD, PhD, on being named a recipient of the @Pan_Financial Foundation's 2026 grant!🎉
Daniel was selected from a national pool of applicants as one of 9 2026 grant recipients for demonstrating a deep dedication to advancing medicine and community.
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Penn Path & Lab Medicine retweetledi
Bispecific antibody engineered extracellular vesicles redirect T cells to prevent postoperative epidural fibrosis ft. Qian Xu, Vijay Bhoj, Zheng Zhang (@PennPathLabMed), Wei Wang (@PennSurgery) & Ellen Puré (@PennVet) @NatureComms nature.com/articles/s4146…
Català
Wonderful to see this recent interview with our own Rajendra Singh, MD on the @Pathologists PATH News Network Daily Edition discussing why pathologists are uniquely positioned to lead the next generation of AI-driven medicine.
Take a look 🔬: youtube.com/watch?v=ckAe3d…
YouTube
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🎉Congratulations to Chris Mignogna, MPH on being named a Penn Medicine Difference Maker! As our Administrative Director for the Division of Precision and Computational Diagnostics he is an asset to the team going above and beyond for patient care.
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Great new paper on engineering a juxtamembrane-targeting CAR T-cell against mesothelin published by the Siegel Lab, headed by our own Don Siegel, MD, PhD.
🔬: frontiersin.org/journals/immun…
Bruce Levine, Ph.D. 🇺🇦🥼🔬🧬🧪💉@BLLPHD
🚨NEW Engineering a juxtamembrane-targeting CAR T-cell against mesothelin: a novel binder resilient to shed antigen for enhanced efficacy against ovarian and pancreatic cancer Target antigen in cancer matter, so does where on that antigen is targeted. Mesothelin is attractive, but much of it is shed, leaving soluble antigen as a decoy and less target on the tumor. Here is a CAR to hit the membrane-proximal “stump” that remains after shedding. @FrontImmunol @PennMedicine frontiersin.org/journals/immun…
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In a recent publication in @CellPressNews Penn Medicine researchers including @carlhjune created a generalizable strategy to identify new targets for CAR T cell therapy utilizing #AI.
Penn Medicine Article 🔬: pennmedicine.org/news/ai-framew…
Cell paper 🔬: cell.com/cell/abstract/…
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A recent publication by @anusaksena in Blood Advances highlights the promising DNA methylation-based classification of hematolymphoid neoplasms utilizing machine learning.
🔬: ashpublications.org/bloodadvances/…
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Penn Path & Lab Medicine retweetledi
Robust footprinting with sample-specific Tn5 bias correction for bulk & single cell ATAC-seq ft. Yuxuan Lin, @NancyZh60672287 (@Wharton), Hanzhi Wang (@pennbioeng) & @parkercwilson (@PennPathLabMed) @NatureComms nature.com/articles/s4146…
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@DrNetto has a new 🎙️Precision Pathology Podcast out! In this episode, he discuss a recent publication in @NatureCancer by Vassy and colleagues on the development of a personalized genomic risk model to improve precision in prostate cancer screening.
🔬: podcasts.apple.com/us/podcast/lev…
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Wonderful to see Sara Cherry, PhD, sharing her knowledge in this @whyy piece on vector-borne diseases and how to combat them this summer with all its ticks and mosquitos. Great to see the real-world impact of our work!
🔬: whyy.org/articles/bug-s…
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A big thank you to Parker Wilson, MD, PhD, for hosting the last Grand Rounds of the season!
It was a great presentation on somatic copy number alteration and pro-oncogenic factors as drivers of non-neoplastic disease that taught us a lot and sparked great discussion.
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Penn Path & Lab Medicine retweetledi
New CAR T treatment opens doors for kidney patients ft. Ali Naji (@PennSurgery), Mary Kaminski, @krjmd (@Penn_Transplant), Vijay Bhoj, @malekkam1, @carlhjune, Nicholas Brown (@PennPathLabMed), Sabiha Hussain (@PennKidney) & @AlGarfall (@PennCancer) tinyurl.com/ykvbx4c4
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🎉Congrats to @carlhjune on being one of 3 scientists awarded the Tang Prize in Biopharmaceutical Science 🏆 for his work in developing CAR T cell therapies! This prestigious prize is awarded every 2 years to recognize revolutionary research efforts.
🔬: tang-prize.org/en/media_detai…
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Penn Path & Lab Medicine retweetledi
New research out in @FrontImmunol provides insight into the generation of functional canine TIL products for solid tumors ft. @VeethikaPandey (#CCI), Kay Foos (@Penn_CBIO), @DJPowellLab (@PennPathLabMed) & Nicola Mason (@PennVet) frontiersin.org/journals/immun…
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🎉Huge congratulations to this year's graduating classes of residents and trainees! 🎓
We are so proud of you and inspired by what you will be doing next. Enjoy this impressive achievement!! 🍾
Further congratulations to this year's department award winners!
Philadelphia, PA 🇺🇸 English
Thank you to @arjunrajlab for leading a great presentation at today's Grand Rounds on the potential for using agentic #AI in research! There are many exciting possibilities and the presentation sparked good discussion.
Millbourne, PA 🇺🇸 English