Roger Moreira

22 posts

Roger Moreira

Roger Moreira

@RKMoreira

Pathologist at Mayo Clinic, Rochester, MN, USA, specializing in GI and hepatic pathology. My good opinions are my own.

Katılım Nisan 2021
48 Takip Edilen130 Takipçiler
Roger Moreira
Roger Moreira@RKMoreira·
A philosophical thought for these times of division - political, scientific, or otherwise: “We can never know when dissent harbors truth, and since all progress was once dissent, we must learn to tolerate it and support systems and institutions that will allow its existence.”
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Roger Moreira
Roger Moreira@RKMoreira·
Good political institutions are those that make it as easy as possible to detect whether a ruler or policy is a mistake, and to remove rulers or policies without violence when they are. David Deutsch, The Beginning of Infinity; and Karl Popper, The Open Society and its Enemies.
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Roger Moreira
Roger Moreira@RKMoreira·
Scientists can be dogmatic, ill-intentioned, equivocated, greedy, malevolent, unjust, politically possessed, outright mad, or plain stupid. Those are problems of people, not of science.
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Roger Moreira
Roger Moreira@RKMoreira·
Karl Popper, Austrian-British philosopher of science and epistemology. But maybe he’s related to Hans Popper? That would be really cool.
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Roger Moreira
Roger Moreira@RKMoreira·
British physicist David Deutsch is one of the most brilliant minds of our time. His improvements on Popperian epistemology and the notion that all knowledge is born out of conjecture and can only grow within a "culture of criticism" is key to understanding science and progress.
Roger Moreira tweet media
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Roger Moreira
Roger Moreira@RKMoreira·
"Our knowledge of the laws of nature are far superior to our intuition, which after all was formed in the past and under a very narrow set of circumstances." David Deutsch
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stephen lagana
stephen lagana@stephen_lagana·
@Vik_deshpandeMD I'll be the luditte and say no real impact. Maybe tiny little apps w/ <5% impact on workflow, but mainly it seems like an extra expense and logistics problem wo massive benefit. In other words, solution in search of problem.
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Vikram Deshpande
Vikram Deshpande@Vik_deshpandeMD·
Machine learning in Anatomic Pathology - within the next 10 years
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Roger Moreira
Roger Moreira@RKMoreira·
Never attribute wrongdoing to malevolence or conspiracy without considering randomness and sheer stupidity first.
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Roger Moreira
Roger Moreira@RKMoreira·
@DougSimonetto Doug and Davide, congratulations and my wishes for a very happy marriage to you!!
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Doug Simonetto, MD
Doug Simonetto, MD@DougSimonetto·
“No union is more profound than marriage, for it embodies the highest ideals of love, fidelity, devotion, sacrifice, and family. In forming a marital union, two people become something greater than once they were.” Justice Kennedy, 2015 #D&D #justmarried #loveislove #HappyPride
Doug Simonetto, MD tweet mediaDoug Simonetto, MD tweet media
Minnesota, USA 🇺🇸 English
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Roger Moreira
Roger Moreira@RKMoreira·
Science is what we call the one and only method of systematically correcting our misconceptions about objective reality.
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Roger Moreira
Roger Moreira@RKMoreira·
@kriyer68 ... certainly worth studying though. Thanks for your interest, take care!!
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Kalyani Bambal
Kalyani Bambal@kriyer68·
@RKMoreira Totally awesome work.Why are Voronoi figures pentagons as against normal liver cell hexagons?
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Roger Moreira
Roger Moreira@RKMoreira·
When pathology meets computational geometry: Voronoi-based liver zonation algorithm built solely from the location of central veins. Many novel zonation tools for digital analysis in the works. Big thanks to the whole team!! nature.com/articles/s4159…
Roger Moreira tweet mediaRoger Moreira tweet mediaRoger Moreira tweet media
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Roger Moreira
Roger Moreira@RKMoreira·
@kriyer68 continuing... (formed by regular hexagons). With the distribution of central veins, the resulting shapes of lobules are variable, but mostly with 5-7 sides in our study of normal livers. Regarding liver cells, I'm not sure the resulting diagram would be mostly hexagons...
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Roger Moreira
Roger Moreira@RKMoreira·
@kriyer68 Thank you Kalyani. It's and interesting questions. Voronoi diagrams will yield convex polygons and their shape will depend on the distribution of their "seeds" (roughly their middle point). If all seeds were equidistant, the resulting diagram would be a honeycomb pattern...
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Roger Moreira
Roger Moreira@RKMoreira·
The beauty of Voronoi diagrams in nature: plates of tortoise shell, fur pattern of giraffes, dragon fly wings and, why not, the liver!
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Roger Moreira
Roger Moreira@RKMoreira·
“I think, therefore I exist”. The idea of analyzing the liver with Voronoi diagrams came into existence inspired by this - a partitioning method for the universe first conceptualized by Rene Descartes in 1644. Striking pattern similarity with pig liver.
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