Roger Moreira

Check out 👉🏼 talk here by @RKMoreira @mayocliniclabs @rondell_graham @MayoClinicPath @MayoClinic AI in #gastrointestinalpath. Models to est eosinophils & hepatic iron. @Aiforia Digital Pathology: Artificial Intelligence Models in Ga... youtu.be/XeeD_tb6Tdk via @YouTube

A philosophical thought for these times of division - political, scientific, or otherwise: “We can never know when dissent harbors truth, and since all progress was once dissent, we must learn to tolerate it and support systems and institutions that will allow its existence.”

Good political institutions are those that make it as easy as possible to detect whether a ruler or policy is a mistake, and to remove rulers or policies without violence when they are. David Deutsch, The Beginning of Infinity; and Karl Popper, The Open Society and its Enemies.

Scientists can be dogmatic, ill-intentioned, equivocated, greedy, malevolent, unjust, politically possessed, outright mad, or plain stupid. Those are problems of people, not of science.

Karl Popper, Austrian-British philosopher of science and epistemology. But maybe he’s related to Hans Popper? That would be really cool.

British physicist David Deutsch is one of the most brilliant minds of our time. His improvements on Popperian epistemology and the notion that all knowledge is born out of conjecture and can only grow within a "culture of criticism" is key to understanding science and progress.

"Our knowledge of the laws of nature are far superior to our intuition, which after all was formed in the past and under a very narrow set of circumstances." David Deutsch

@stephen_lagana @Vik_deshpandeMD "A solution in search of a problem", haha I'll use your quote, Steve!

@Vik_deshpandeMD I'll be the luditte and say no real impact. Maybe tiny little apps w/ <5% impact on workflow, but mainly it seems like an extra expense and logistics problem wo massive benefit. In other words, solution in search of problem.

Machine learning in Anatomic Pathology - within the next 10 years

Never attribute wrongdoing to malevolence or conspiracy without considering randomness and sheer stupidity first.

@DougSimonetto Doug and Davide, congratulations and my wishes for a very happy marriage to you!!

“No union is more profound than marriage, for it embodies the highest ideals of love, fidelity, devotion, sacrifice, and family. In forming a marital union, two people become something greater than once they were.” Justice Kennedy, 2015 #D&D #justmarried #loveislove #HappyPride

Science is what we call the one and only method of systematically correcting our misconceptions about objective reality.

@kriyer68 ... certainly worth studying though. Thanks for your interest, take care!!

@RKMoreira Totally awesome work.Why are Voronoi figures pentagons as against normal liver cell hexagons?

When pathology meets computational geometry: Voronoi-based liver zonation algorithm built solely from the location of central veins. Many novel zonation tools for digital analysis in the works. Big thanks to the whole team!! nature.com/articles/s4159…

@kriyer68 continuing... (formed by regular hexagons). With the distribution of central veins, the resulting shapes of lobules are variable, but mostly with 5-7 sides in our study of normal livers. Regarding liver cells, I'm not sure the resulting diagram would be mostly hexagons...

@kriyer68 Thank you Kalyani. It's and interesting questions. Voronoi diagrams will yield convex polygons and their shape will depend on the distribution of their "seeds" (roughly their middle point). If all seeds were equidistant, the resulting diagram would be a honeycomb pattern...

@stephen_lagana @IHC_guy @rondell_graham @Heidi_Lehrke_DO @nasir_pathMD @b_histopath @AShenoy_MD @ReetPaiMD1 @Marykingir @ALBoothMD @CArnold_GI @MArnold_PedPath @JMGardnerMD @Sara_Jiang @sanamloghavi @smlungpathguy @natasharekhtman @Chucktowndoc @Teclis82 @JLHornick @DennisOMalleyMD @emckaymd @LiverPath_HPHS @Vik_deshpandeMD @Aiims1742 @ISIMMweb Hey Steve! Not a social media guy, but decided to give it a shot as a place to exchange ideas. Hope all is well, it’s been too long man!

@IHC_guy @rondell_graham @RKMoreira @Heidi_Lehrke_DO @nasir_pathMD @b_histopath @AShenoy_MD @ReetPaiMD1 @Marykingir @ALBoothMD @CArnold_GI @MArnold_PedPath @JMGardnerMD @Sara_Jiang @sanamloghavi @smlungpathguy @natasharekhtman @Chucktowndoc @Teclis82 @JLHornick @DennisOMalleyMD @emckaymd @LiverPath_HPHS @Vik_deshpandeMD @Aiims1742 @ISIMMweb Very cool study. And v v cool to see @rkmoreira on Twitter

@rondell_graham @Allende_DS @Dr_Vijay_Shah @SumeraIlyasMD @DougSimonetto @johnhart20 @RaulSGonzalezMD Agree completely!! Hopefully smarter people out there will join in to crack that next puzzle.

@RKMoreira @Allende_DS @Dr_Vijay_Shah @SumeraIlyasMD @DougSimonetto @johnhart20 @RaulSGonzalezMD Really cool look @ the computational geometry of the liver. If there is a normal math relationship 2 the structures, could there b specific recurrent mathematical changes in specific diseases

The beauty of Voronoi diagrams in nature: plates of tortoise shell, fur pattern of giraffes, dragon fly wings and, why not, the liver!

“I think, therefore I exist”. The idea of analyzing the liver with Voronoi diagrams came into existence inspired by this - a partitioning method for the universe first conceptualized by Rene Descartes in 1644. Striking pattern similarity with pig liver.