RNA-Seq Blog

RNA sequencing is revealing how Alzheimer's disease changes individual brain cells across diverse populations. The findings identify shared and population-specific molecular signatures that could improve future diagnostics and therapies. @ColumbiaMed rna-seqblog.com/cell-type-sign…

RNA sequencing with Rectangle recovers detailed cell type information from bulk RNA sequencing data. The approach supports biomarker discovery and large-scale studies without single-cell sequencing for every sample. @uniinnsbruck @DiSC_uibk rna-seqblog.com/rectangle-robu…

RNA sequencing paired with AI is helping researchers recover cell-specific regulatory signals from bulk sequencing data. DeepDETAILS makes it possible to extract more biological insight from existing datasets and improve studies of gene... @Cornell rna-seqblog.com/deepdetails-hi…

RNA sequencing is helping connect RNA sequence to protein production, and seq2ribo predicts ribosome behavior using sequence alone. The approach could support the design of improved mRNA therapeutics, vaccines, and synthetic biology... @CarnegieMellon rna-seqblog.com/seq2ribo-struc…

RNA sequencing and spatial genomics are giving researchers a clearer view of tumor biology. STGBench generates realistic paired DNA and RNA sequencing datasets to improve benchmarking of spatial analysis tools. - @XJTU_China rna-seqblog.com/stgbench-seque…

Single-cell RNA sequencing mapped the cells and genes that regulate bone health, uncovering hundreds of previously unknown bone-related genes and revealing an important role for blood vessel cells in bone repair. @UNSW @GarvanInstitute @imperialcollege rna-seqblog.com/genetic-mappin…

RNA sequencing is uncovering previously hidden long non-coding RNA isoforms. NanoncRNA-Seq improves full-length transcript detection, providing a more complete picture of gene regulation and transcriptome complexity. - @CAS__Science rna-seqblog.com/nanoncrna-seq-…

RNA sequencing is revealing how aging alters gene expression and RNA splicing. Combining short-read and long-read approaches is uncovering molecular changes that may guide future healthy aging therapies. - @NorthwesternMed rna-seqblog.com/examining-the-…

RNA sequencing can miss broken RNA molecules that carry important biological information. A newly engineered RNA-repair ribozyme could help capture these hidden RNAs and improve disease research. - @NotreDame - @NDBios - @UChicago rna-seqblog.com/researchers-sh…

Single-cell RNA sequencing is revealing gene activity one cell at a time. Amaranth improves transcript reconstruction, helping researchers study RNA isoforms, gene regulation, and cellular diversity with greater accuracy. - @ChildrensPhila - @penn_state rna-seqblog.com/amaranth-enhan…

RNA sequencing is helping researchers uncover tRNA modifications that influence health and disease. QutRNA2 speeds analysis of direct RNA sequencing data, making large-scale studies faster and more accurate. - @HeidelbergU - @nanopore rna-seqblog.com/qutrna2-robust…

RNA sequencing data paired with AI is improving how researchers identify microRNA targets and binding sites. MiRformer delivers accurate, interpretable predictions that can advance RNA biology and therapeutic development. - @mcgillu - @Mila_Quebec rna-seqblog.com/mirformer-a-du…

Single cell RNA sequencing is uncovering how kidney immune cells coordinate tissue repair after injury, providing new clues for therapies that promote recovery and prevent chronic kidney disease. - @Tulane rna-seqblog.com/study-reveals-…

Single nucleus RNA sequencing is revealing new therapeutic targets in rare sinonasal cancers, helping researchers develop more precise treatment strategies based on each tumor's unique biology. - @LMU_Muenchen rna-seqblog.com/single-nucleus…

RNA sequencing combined with ChiTaRS and ChiTaH improves detection of disease associated chimeric RNAs, supporting biomarker discovery and targeted therapies for cancer and neurodegenerative diseases. - @ubarilan rna-seqblog.com/chimeric-rnas-…

Single cell RNA sequencing combined with AI improves T cell subtype identification in cancer, helping researchers better understand tumor biology and develop more targeted immunotherapies. - @UMich rna-seqblog.com/scpankd-new-ai…

RNA sequencing data from nearly 9,000 participants has been added to the NIH All of Us Research Program, expanding one of the world's most valuable resources for precision medicine research. - @NIH - @AllofUsResearch rna-seqblog.com/nihs-all-of-us…

Single cell RNA sequencing is mapping hormone signaling across the human body, creating a powerful resource for studying endocrine biology, metabolism, and disease. - @Cambridge_Uni rna-seqblog.com/a-hormone-cell…

Single cell RNA sequencing reveals that many cells exist along continuous landscapes rather than fixed categories, providing new insights into immune cell behavior and future immunotherapies. - @bengurionu rna-seqblog.com/rethinking-imm…

RNA sequencing and artificial intelligence are improving predictions of immunotherapy response by uncovering complex immune patterns that help identify patients most likely to benefit from treatment. - @harvardmed rna-seqblog.com/ai-model-impro…