Rebecca Puddester (she/her)

669 posts

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Rebecca Puddester (she/her)

Rebecca Puddester (she/her)

@RPuddRN

Med/Surg RN, MN, PhD(c). Interested in cancer genomics in nursing, POR. A perpetual work-in-progress. Learning and unlearning.

Newfoundland and Labrador Katılım Kasım 2012
221 Takip Edilen160 Takipçiler
Rebecca Puddester (she/her) retweetledi
Yakup Ergün
Yakup Ergün@dr_yakupergun·
Genetic mutations/alterations by cancer region👇
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Sevtap Savas, PhD (she/her)
Will proudly present the Community of Practice at the annual @CANO_ACIO conference this week in St. John's ❤️ See you there! If anyone is interested in Patient Engagement in Cancer Research and would like to join this virtual community, see here: cancer.ca/en/research/fo…
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Rebecca Puddester (she/her) retweetledi
Broadbent Institute
Broadbent Institute@broadbent·
Private nursing agencies are a “band-aid” to our public health care system staffing crisis according to Prof Joan Almost (@jmalmost), author of the new @CFNU report: “Opening the black box: Unpacking the use of nursing agencies in Canada” Listen to the latest Perspectives Journal Podcast episode: perspectivesjournal.ca/opening-the-bl…
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Rebecca Puddester (she/her) retweetledi
Dra. María Natalia Gandur Quiroga
💫🌟Early-Onset Cancers: Unraveling Biological Causes and Clinical Implications🌟💫 @OncoAlert 🔷 Understanding Early-Onset Cancers Over the past three decades, the incidence of early-onset (EO) cancers—those diagnosed in individuals under the age of 50—has been rapidly rising. While EO cancers traditionally affected older adults, recent epidemiological data highlight a disturbing increase in diagnoses among adolescents and young adults, notably in cancers like colorectal cancer (CRC) and breast cancer (BC). 🔷 Key Points • Rising Incidence: ➤ The incidence of EO cancers globally increased by 80% from 1990 to 2019, especially in gastrointestinal, colorectal, and breast cancers. ➤ Notably, EO-CRC is projected to account for one-third of all CRC cases by 2030. • Impact of the Exposome: ➤ The rise in EO cancers may be linked to changes in environmental exposures, including diet Westernization, increased consumption of processed foods, exposure to carcinogens, and shifts in lifestyle factors like physical inactivity and obesity. ➤ Environmental pollutants, such as PM2.5 and microplastics, are also suspected contributors. • Challenges in Screening: ➤ Current screening protocols may not be well-suited to EO cancers, especially in CRC, where tumors may develop faster in younger populations. ➤ Innovations like circulating tumor DNA (ctDNA) monitoring could be key in developing more effective, non-invasive screening strategies for early detection. 🔷 Hypotheses on EO Cancer Evolution • Biological Peculiarities: ➤ EO cancers may follow different biological pathways compared to late-onset cancers. There is growing interest in understanding if EO tumors exhibit distinct molecular profiles that affect treatment responses, potentially requiring tailored therapeutic approaches. • Multi-Omics Integration: ➤ Comprehensive multi-omics profiling is essential to uncover the genetic, epigenetic, and transcriptomic features unique to EO cancers. International collaborations and biobanks focusing on EO cancer samples are critical to advancing this research. 🔷 Conclusion The surge in early-onset cancers presents an urgent public health challenge. By integrating epidemiological, environmental, and molecular data, we can develop a deeper understanding of the biology driving these cancers. This approach, referred to as the EO-cancer integrome, could ultimately lead to more effective prevention, diagnosis, and treatment strategies. #EarlyOnsetCancer #CancerResearch #Oncology #PrecisionMedicine #ColorectalCancer #BreastCancer #Exposome #PublicHealth #MultiOmics cell.com/cell-reports-m…
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Rebecca Puddester (she/her)
The oncology genomics SIG serves as a dynamic forum for fostering collaboration, leadership and networking among oncology nurses engaged in various areas, including clinical practice, education, research, clinical practice and administration.
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Rebecca Puddester (she/her) retweetledi
CANO/ACIO
CANO/ACIO@CANO_ACIO·
Our #CANOACIO2024 #AnnualConference is coming up & not only do students get a special rate for the full conference - but there is a FREE #StudentDay at the conference! Follow the instructions to sign up - a student #CANOACIO profile is required.
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