Rachel

Do you work in DNA replication, genome maintenance, chromosome organisation, chromatin maintenance, or a related field? 🧬🔍 Join us for the EMBO | EMBL Symposium 'DNA replication and genome maintenance: from basic biology to human health', bringing together experts and early-career researchers to drive new ideas and collaborations. Abstract submissions are welcome from researchers at all career stages! #EESReplication Session topics • Replisome structure and function • Replication in time and space • Chromatin replication and cell fate • Replication stress and genome stability • Replication-coupled DNA repair • Replication in development, aging, and cancer 📍 EMBL Heidelberg and Virtual 📅 20 – 23 October 2026 📩 Submit your abstract by 28 July: s.embl.org/ees26-13-x

Professor David Sinclair and Harvard researchers reversed aging in mice by up to 75%. Human trials have begun.

Ready to take your #AgingResearch into clinical trials? 🔬 AGE 2026 · Day 1 Session: A Primer on #Geroscience Clinical Trial Design 📅 Tue, June 2 · 1:00–5:00 PM · Ballroom A FDA INDs, biomarkers, dose-finding, TGN & more. Register → bit.ly/4vDrGxG #AGE2026 #Geroscience

Metformin, one of the most commonly prescribed drugs, was thought to work via the liver. Check that. It's primarily through the gut. @NatMetabolism nature.com/articles/s4225…

Read full paper here: doi.org/10.1016/j.cell…

🎀Congratulations to our Advisory Editor Prof. Guang-Hui Liu

From biomarkers to interactions—an important shift in how we study aging.

🔬 Excited to share our new preprint on a translational toolkit for ageing research. We present a multi-modal approach to profile key hallmarks of human ageing, from immune function to mitochondrial activity and mTOR/autophagy. Our aim is to improve standardisation, reproducibility, biomarker discovery, and ultimately clinical translation. biorxiv.org/content/10.648…

How does life build itself? Mechanics. Forces. Cells. Join EMBL Mechanobiology 2026 (@EMBLEvents) 📍 Heidelberg | 📅 June 9–12 🧬 Across cells → tissues → organisms 💡Keynote speakers: Caren Norden & Manu Prakash 🔗 embl.org/about/info/cou…

A new bioRxiv preprint (incl. Andrei Gudkov) views aging through a thermodynamic lens: biological age vs “phenotypic temperature”. Interventions may slow epigenetic clocks, but not necessarily aging trajectories. Are we changing state, not rate? biorxiv.org/content/10.648…

Science advances through people who keep pushing boundaries. 🎀Congratulations to the newly elected members of the National Academy of Sciences @theNASciences 🎊

🔍Aging is not a single pathway problem — it is a systems failure problem. This Biogerontology paper reinforces the shift toward integrative aging biology across stress, metabolism & cellular regulation. 🔗 link.springer.com/article/10.100… #Aging #Geroscience #Senescence

What if mitochondria decide cell fate? Join the Mitochondria & Cell Fate Transitions Conference by @FusionConferences 🧬 Aging | Cancer | Metabolism 📅 May 10–13, 2026 | 📍 Malta 🔗 fusion-conferences.com/conference/197 #Aging #CancerResearch #Mitochondria #Senescence

🔍A compelling perspective on how diet interfaces with epigenetic plasticity and metabolism to regulate aging trajectories.

👴With global population aging accelerating at an unprecedented pace, extending healthy and productive lifespan is becoming one of the most critical challenges of our time. Advancing research in aging biology and disease mechanisms will be key to achieving this goal.

A timely and insightful review on high-throughput screening in ageing drug discovery—together with the authors’ related work in ageing research, it provides a broader perspective on the field. 👉Also see: sciexplor.com/articles/acrt.…

A highly relevant topic—looking forward to this discussion on genome stability.

Aging is becoming truly measurable—this is a major shift in how we understand biology.✍️

Will cell reprogramming with stem cell factors reverse aging? A pilot trial in eye disease will soon be the first test at the tissue level. nature.com/articles/d4158… Feature @Nature by @heidiledford @altos_labs @lifebiosciences

Senescence in cancer: Hallmarks, paradoxes, and therapeutic promise cell.com/cell/abstract/…