Cesar Castillo

"This is fine"

How to lead when you're not in charge

link.springer.com/article/10.100… Immunomodulatory role of oncogenic alterations in non-small cell lung cancer: a review of implications for immunotherapy @ogarrieta @YanHernandezP @maritza_rramos @josemarialucio @RealCaesarCas

Nuevamente nuestros programas especiales y la Unidad de Oncología Integrativa se unen en una jornada de promoción de la salud en el marco del Día Mundial contra el Cáncer. Te esperamos este 4 de febrero, habrá stands informativos, pruebas de detección y pláticas ¡No faltes!

The metabolic costs of cognition Review by Sharna D. Jamadar (@SharnaJamadar), Anna Behler (@Anna_NeuroSci), Hamish Deery (@DeeryHamish), & Michael Breakspear (@DrBreaky) Free access before March 4: tinyurl.com/47c9n65w

In this cohort, we included 446 NSCLC patients who underwent different NGS panels at the National Cancer Institute of Mexico, 65% had no history of smoking. PFS was significantly longer in patients with actionable mutations treated with targeted therapies (19.4m P.001) than in patients without actionable mutations (6.4m) or not treated with targeted therapies (6.6m). Similarly, OS was significantly longer in patients with actionable mutations treated with targeted therapies (89.7m P < .001) than in patients without actionable mutations (17.1m) or not treated with targeted therapies (22.3m). An important step toward improving the clinical outcomes of patients with NSCLC is to ensure wider access to broadmolecular testing and targeted therapies so that patients receive the most appropriate treatment. @Ecaballep @AndresFCardonaZ @UToracica ascopubs.org/doi/10.1200/GO…

Cancer Immunotherapy with Oncolytic Viruses @CellCellPress

En la lucha contra el #CáncerDePulmón todas y todos podemos hacer algo: -Evita fumar o vapear 🚭 -Realiza actividad física diaria 🏃‍♀️🏃🏾‍♂️ -Si cocinas con leña, realízalo al aire libre 🪵 -Si tienes factores de riesgo, acude con tu médico (a) 🧑‍⚕️

Lung Cancer Affects Non-Smokers Too! 15-20% of #lungcancer cases occur in individuals w/no history of smoking. Other risk factors like air pollution, radon & certain occupational exposures contribute to lung cancer risk says the ALA. Stay informed! #LCAM24 #KnowYourRisk #LCSM

Lung cancer remains a global challenge, especially in LMICs with limited access to NSCLC molecular testing. A recent study reveals high EGFR mutation rates and low adherence to adjuvant therapy guidelines. Read our editorial for more insights. @ogarrieta jto.org/article/S1556-…

Simplified view of metabolism. Proteoforms & metabolites are abstracted. Many of the parameters are unknown. Regulatory links are missing.

Yesterday, the FDA approved the first drug for schizophrenia with a new mechanism of action for more than half a century. For more on this mechanism - targeting muscarinic acetylcholine receptors - here's a recent review tinyurl.com/mwpahd99 rdcu.be/dVhpp

Cancer in a nutshell

Know these anatomical triangles

The crosstalk between metabolism and translation dlvr.it/TD1fbs