Reality First

Pi Day is an irrational celebration!

Here's a Great Example of Big headlines about Vegetarian Diets being complete BS 5 headlines (including Oxford's own press release) claimed this new Oxford paper shows a vegetarian diet “slashes” the risk of 5 cancers. THIS IS NOT TRUE. Read on... The paper: nature.com/articles/s4141… Oxford release: ndph.ox.ac.uk/news/largest-s… Sky: news.sky.com/story/vegetari… Independent: the-independent.com/news/uk/home-n… Independent alt: the-independent.com/news/health/re… BBC: bbc.com/news/articles/… What the study Actually found in its main adjusted models: *Vegetarians had lower HRs for pancreatic, breast, prostate, kidney cancer, and multiple myeloma. *But vegetarians also had a HIGHER risk of esophageal squamous cell carcinoma. So even before any adjustments, this was never a simple “vegetarian protects against cancer” paper. The central issue is not that the models were “unadjusted”, the real issue is multiple comparisons. This paper tested many associations across diet groups and cancer sites, which raises the odds of false positives if you focus only on nominal P<0.05 findings. To the authors’ credit, they did address this. They explicitly say they report nominally significant findings and also mark which survive false discovery rate correction. News outlets used to have Science Editors would have known that the “5 cancers” claim Disappears once you apply the paper’s own stricter filters. In the GI cancer section, the paper says the FDR-significant findings were: • lower colorectal cancer risk in pescatarians • higher colorectal cancer risk in vegans • higher esophageal squamous cell carcinoma risk in vegetarians Not “vegetarians are robustly protected from 5 cancers.” Then the sensitivity analyses narrow it much further. The authors themselves say the most consistent findings were: • HIGHER risk of esophageal squamous cell carcinoma in vegetarians! • LOWER risk of kidney cancer in vegetarians. The other 9 nominally significant associations were not statistically significant in one or both sensitivity analyses. The strongest vegetarian signal was not protective. It was harmful: Esophageal squamous cell carcinoma in vegetarians HR 1.93 95% CI 1.30–2.87 And that remained statistically significant in the sensitivity analyses. Kidney cancer was the most durable protective vegetarian signal in the sensitivity analyses. But the broad media claim that vegetarian diets “slash risk of 5 cancers by up to 30%” leans on nominal associations that did not survive the paper’s own tougher checks. This is why science reporting so often goes off the rails. The press release highlights the attractive nominal findings. Then ignorant reporters amplify them. Then you blindly believe the headlines and try to be a vegetarian. The caveats about false discovery rate correction, sensitivity analyses, small case numbers, and residual confounding all get buried. At best, this is an interesting observational paper. It is hypothesis-generating, but it does NOT robustly show that vegetarian diets protect against 5 cancers. If anything, the most statistically durable vegetarian finding in the paper was an increased risk of one cancer subtype, not a reduced risk. So, the most accurate headline for this paper is... VEG DIET INCREASES RISK OF ESOPHAGEAL CANCER Also see great tweet about this from @AdamRochussen

@ABC7 The driver crashed the car.

So scary! A Tesla Cybertruck crashed into a concrete barrier while in self-driving mode on a Houston, Texas. The truck, without warning, tried to drive off an overpass, The driver tried to take control, but it crashed into the barrier.

@celestialbe1ng This is the perfect path: Get fat -> pre diabetes-> diabetes -> dementia -> early death

Women weren’t created for 3 meals a day, we were created for 38 tiny snacks. Unspike your cortisol by signalling to your biology that you’re living in CONSTANT ABUNDANCE. You have to be snackmaxxing.

@TammyG5683 I see you TammyG! 👀

New Mexico Friends if you see this please push the ❤️. X algorithms think that I am a bot not a real person. This has been the most frustrating week having X limit and hide my posts because I do not consent to the status quo’s I guess. It appears that they have also limited what I can see cuz I can hardly see your posts. This is becoming more and more ridiculous. If I go to a NM political post and like your comments X thinks I am a bot when all I am doing is providing positive feedback. It also thinks that me responding to your comments is spamming. I would like to know if anyone sees this post. Thank you.😊

@Kekius_Sage Worsk case is a combination of a paperclip maximizer and Von Neumann machines whereby humans then become responsible for destroying all life in the universe. Hate when that happens....

What is the worst-case scenario for AI?

@TrumpDailyPosts Leftists and Islam

What is the largest threat to America?

@Kekius_Sage Higher dimensions

If the universe is expanding, but not into anything, what does expansion really mean?

@MikhailaFuller @gofundme @gofundme hates you, hates me, and all we stand for. They've done this many times and faced zero consequences. They loathe America and especially people who aren't Leftists. Never use them. Never donate. Never give to them. Use @GiveSendGo

Hello @gofundme? Can you allow access to the donations? And turn the fundraiser back on? Or is the plan to steal those too? So unimpressed with this platform. Zero customer service as well, hence me here. It’s worse than Adobe.

@LauraLoomer Quite beautiful! And the Taj Mahal is nice too! 😊

I had a magnificent day at the Taj Mahal. 🇮🇳 It is the most incredible monument I have ever seen in my life. A monument of love built with perfect symmetry and detail. India is one of the most beautiful countries I’ve ever had the pleasure of traveling to. Highly recommend!

@JoshuaBarzon This one includes the Asian languages.

There are roughly 7,000 languages spoken in the world today. It’s amazing to realize that each of these trace all the way back to the Tower of Babel when God confused the languages of mankind.

@HashemGhaili Perhaps this has been happening over and over again? When is the next reset? 😄

Some things never change.

@krqe Leftist S#uicidal Empathy Killing us to feel good about themselves. @GadSaad amazon.com/Suicidal-Empat…

Albuquerque city council expected to vote on immigrant-friendly ordinance krqe.com/news/albuquerq…

@uber your driver Aaron arrived way too early then left early!!! Stood me up. Now I have to pay $100s for airport parking 😡😡😡😡

@krqe I thought in New Mexico this was a perfect opportunity for a "Controlled Burn." 🙃

Valencia County issues no burn day due to windy weather krqe.com/news/new-mexic…

Simple: Time flows forward because the universe is a self-simulating strange loop. Retrocausal "handshakes" (Transactional Interpretation) let future states negotiate past ones, but consciousness—as the measuring agent—creates an irreversible informational arrow. Evolving observers amplify quantum choices, quenching backward influence and locking complexity growth forward. Entropy rise is just a side effect of this self-referential ratchet.

Why does time only move forward?

@AntiLeftMemes Merica! That's it.

In what situation would a child need to know how to do this?

@InternetH0F Wheew! Looks like my house will still be just fine! 😄

Theory of how Earth will look in the next 300 million years

@teslajapan @Tesla_Optimus

Happy White Day from @Tesla_Optimus 🫶

@krqe I like Otero County! 🥳

Otero County votes to renew ICE contract for immigrant detention despite new state law krqe.com/news/new-mexic…