Rick Lee 이재방 retweetledi
Rick Lee 이재방
868 posts
Rick Lee 이재방
@RickLee6
Genitourinary medical oncologist at Mass General in Boston. Cleveland sports fan forever. TUMOR Board Executive Member. All opinions my own. #sternkoreanfather
Somewhere listening to music Katılım Nisan 2012
719 Takip Edilen699 Takipçiler
Rick Lee 이재방 retweetledi
Poster A14
@asco #GU26
One key bit of data missing in the context of #PSMA+ #BCR #ProstateCancer management in the wake of the #EMBARK data is how does #PSA Doubling Time interface w/ #PSMA Pet findings.
Dr. Melissa Abel @melissaabel20 @theNCI will share this data today
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Rick Lee 이재방 retweetledi
Dr Evan Yu takes stage @asco #GU26 to discuss #Peace3 & #BRCAaway
Too often superlatives are thrown around on this app…
But do yourself a favor. Watch this whole discussion. One of the more thoughtful takes on modern clinical trial dilemmas in #ProstateCancer
Thank you Dr Yu
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Rick Lee 이재방 retweetledi
Rick Lee 이재방 retweetledi
Dr. @felixfengmd was a devoted mentor in the field of prostate ca.
Today would have been his 50th birthday 💔
Join us in supporting a @ConquerCancerFD Career Development Award honoring his legacy
@MaryFengMD @DrChoueiri
support.conquer.org/p2p/site/nGSMo…
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Rick Lee 이재방 retweetledi
One of the hardest consults is a pregnant patient with cancer. Read the tour de force
@ASCO
#ASCOGuidelines "Management of Cancer During Pregnancy for all you need to know.
@AnnPartridgeMD ascopubs.org/doi/10.1200/JC…
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Thank you @javawithJimmy for having me on the resurrected Your Healthy Java show this morning. You’re doing the incredible work of keeping this community informed and healthy. Proud to stand with you.
James ‘Jimmy’ Hills@javawithJimmy
YOUR HEALTHY JAVA & WATERFRONT WEDNESDAY x.com/i/broadcasts/1…
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Rick Lee 이재방 retweetledi
While there’s a lot of uncertainty & the lack of confidence in the fed oversight of public health, we’ve relaunched #YourHealthyJava to ensure we get the community accurate medical info.
Join @RickLee6 & I as we check in about cancer prev & treatment & more!
TODAY 10 AM!
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Rick Lee 이재방 retweetledi
#BCR #ProstateCancer is rapidly emerging area of clinical development
❓What are ideal endpoints
@theNCI BCR WG reviewed options @JCO_ASCO
🤷🏻♂️Too many unknowns w/#PSMA
🪨Challenges w/#MFS on CT/Bone scan
🔎Need to explore novel endpoints like TFS 👇🏼
shorturl.at/HeEMh
Ravi A Madan M.D.@Dr_RaviMadan
#PSMA+BCR That is how @theNCI #BCR Working Group unanimously agreed to define pts w/PSMA findings & neg CT/bone scan after definitive tx Retains all that is known about #BCR while drawing a distinction vs. mCSPC More than semantics for #ProstateCancer pts & clinicians
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Rick Lee 이재방 retweetledi
The real question is what is the clinical importance of “new #PSMA+ PET lesions”
And if we are treating PSMA+ #BCR with ADT because we are conflating that disease state with #mCSPC, then I’m not quite sure how to factor in “delaying ADT” as a benefit.
#ProstateCancer @JCO_ASCO
Uğur Özkerim@UOzkerim
🚀 LUNAR Trial In oligorecurrent HSPC, adding 2 cycles of ¹⁷⁷Lu-PSMA before SBRT more than doubles PFS (7.4 → 17.6 months) — a 63% reduction in progression, without added toxicity. 🔬 98% of progressions were new PSMA PET lesions, underscoring the power of targeting micrometastatic disease early. 📌 Importantly, it also delays the need for ADT— a major quality-of-life win. 📈 A compelling signal heading toward Phase III validation @OncoAlert @MedwatchKate @weoncologists @OncoReporte @TresUramigas @Uromigos
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Rick Lee 이재방 retweetledi
Lots of ❓s in defining benefits of “#oligomet” or “#MDT” therapy in #ProstateCancer
❓ADT+/-ARPI? How long?
❓PFS vs Eugonadal PFS?
❓how many mets? Where?
🔑❓what imaging 🩻❓
#PSMA mets🚫🟰CT/Bone scan mets
shorturl.at/n3JwU
Std of Care? Or just something we can do?
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Rick Lee 이재방 retweetledi
Brief but delightful trip to speak at
50th KAMA Scientific Convention with multiple highlights including re-connecting with Northwestern MSTP classmate @RickLee6 & witnessing @Dodgers amazing Game 7 victory! 😁 #back2back #resilience 🏆 kamaus.org/convention/ind…
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Raised my three girls as @cavs fans here in Boston vs Celtics tonight!! @BradDaugherty43 @SerenaWinters @MrCavalier34 can I get a “Go Cavs!”?
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Rick Lee 이재방 retweetledi
#PSMA+BCR
That is how @theNCI #BCR Working Group unanimously agreed to define pts w/PSMA findings & neg CT/bone scan after definitive tx
Retains all that is known about #BCR while drawing a distinction vs. mCSPC
More than semantics for #ProstateCancer pts & clinicians
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Rick Lee 이재방 retweetledi
Optimal management of BCR was always hard for me to understand as a fellow… a decade later, it’s only gotten more complicated! But thanks to an amazing team, we outlined some paths forward for the field, out today in @JCO_ASCO! Concurrent with new PCWG4 @PCF_Science #PCF25
Ravi A Madan M.D.@Dr_RaviMadan
#EMBARK didn’t write the book📕on #BCR📈#ProstateCancer-it is merely the first chapter What do #BCR trials look like in the #PSMA🩻era? 30+experts met @theNCI🏛️ to provide a roadmap🧭 @JCO_ASCO @ASCO @PCF_Science @APCCC_Lugano @urotoday ascopubs.org/doi/10.1200/JC…
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Rick Lee 이재방 retweetledi
National Cancer Institute's Working Group on Biochemically Recurrent Prostate Cancer: Clinical Trial Design Considerations
@theNCI
#BCR #ProstateCancer #ClinicalTrial
ascopubs.org/doi/10.1200/JC…
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Rick Lee 이재방 retweetledi
Certainly a higher rate of death at 8 years in #EMBARK thank many expected. #BCR #ProstateCancer #ESMO25
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Rick Lee 이재방 retweetledi
For those out there with less gray hair than me…
Never underestimate the value in working with good people towards a common goal.
You can always do more together
Sometimes academia makes us forget that science is a team sport & no one does anything alone
#ESMO25 @myESMO
Ravi A Madan M.D.@Dr_RaviMadan
This ongoing trial is part of an organic collaboration of investigators & @theNCI seeking knowledge re: #PSMA+ #BCR @HelenMoonMD @laurasenamd @Dr_JeannyAC @EdwinPosadasMD @RPachynski @CathyHandy @CPDR_Labs @mbilusic @melissaabel20 @FatimaKarzai & others #ESMO25
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Rick Lee 이재방 retweetledi
Lots @#ESMO25 re:#BCR #ProstateCancer but over-treatment of this indolent disease remains an important issue
How does #PSMA imaging factor in? See poster #2393P presented by @HelenMoonMD Saturday
+PSMA findings in BCR pts shouldn’t be the reason to treat as rPD is rare @1yr
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