RogerMulet

34 posts

RogerMulet

RogerMulet

@RogerMulet

NL-based bioinformatician. Interested in epigenetics, leukemia and science in general. I support evidence-based practices.

Katılım Temmuz 2021
77 Takip Edilen34 Takipçiler
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Ruud Delwel
Ruud Delwel@DelwelRuud·
Read our Spotlight article: One for All and All for One: New Insights into Enhancers Driving MYC Dysregulation aacrjournals.org/bloodcancerdis… Its a commentary on the very nice paper by Iyer and colleagues!
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RogerMulet
RogerMulet@RogerMulet·
@tkulogo @RichardDawkins First, Europe wants to end this war, but only in terms that don't encourage Russia to start one in the near future. Territorial concessions to expansionist powers don't achieve lasting peace. Second, refusing to pay isn't an excuse to side with the aggressor.
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Tim Kulogo
Tim Kulogo@tkulogo·
@RichardDawkins You really need to stop commenting when you haven't watched the whole thing. You've done this on other issues too. It's harming your credibility. The US can't afford to pay for wars in Europe that European countries don't want to end. Strive for peace, or pay for it yourself.
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Richard Dawkins
Richard Dawkins@RichardDawkins·
Among the least likeable of human beings are bullies, and those who toady to them. Trump – Putin’s Poodle – manages to combine both: his arrogant bullying of Zelensky, in the service of his barfworthy toadying to the Russian bully. #comments" target="_blank" rel="nofollow noopener">freethoughtblogs.com/pharyngula/202…
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Dorien Pastoors
Dorien Pastoors@d_pastoors·
Second preprint now on biorxiv!! 🧵⬇️ thanks to all our co authors @MarijeHavermans @RogerMulet @SmeenkLeonie and others i cant find on here ! Also on bluesky 🦋: bsky.app/profile/dpasto… @erasmusmcblood
Ruud Delwel@DelwelRuud

Excited to share our preprint (@D_Pastoors): "MECOM is a master repressor of myeloid differentiation through dose control of CEBPA in acute myeloid leukemia"! biorxiv.org/content/10.110… MECOM is a TF whose overexpression leads to aggressive AML and with an immature phenotype. [1/15]

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RogerMulet
RogerMulet@RogerMulet·
@DavidMavis11 @LDS_Dems You are blaming the deaths on the Ukrainian president for refusing to bend over to foreign demands when threatened with war? That's an interesting perspective. Let Putin have Alaska when he asks for it then, or the entire US for that matter. Why cause unnecessary deaths?
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David Mavis
David Mavis@DavidMavis11·
That’s false, he is responsible for all the deaths since he listened to Boris Johnson and rejected the peace deal he had already agreed to with Russia. He negotiated the deal and then rejected it in favor of promises of massive aide. His people and country would have been spared all the destruction. He is a weak leader who gave into western military interests at the cost of his country
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Dem Saints
Dem Saints@LDS_Dems·
I do not understand the Republican hatred of Zelensky. He is the Churchill of our times. He has worked tirelessly for the freedom of his people. He is everything they claim to want in a leader....yet they hate him. I don't get it. (Actually I do know why.....)
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RogerMulet
RogerMulet@RogerMulet·
@TheMitchMitchem @ylecun Prices have increased similarly everywhere outside the US. It has very little to do with who was in power at the time, and a lot with a global pandemic that disrupted supply networks. However, the US has experienced much higher economic growth than other developed countries...
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Yann LeCun
Yann LeCun@ylecun·
Lowest unemployment in 55 years, low inflation, super-high GDP growth compared to other developed countries, deficit down after the Covid peak, illegal immigrant inflow way down since post-Covid peak. Yet, within the Trump-Musk-Vance reality distortion field, the country is bankrupt, inflation is through the roof, and borders are overrun by hordes of subhumans.
Lia the Trader 👸💸@Liathetrader

The unemployment rate is currently about 4.1%, the lowest since 1968. Inflation is low, at 2.2%. GDP growth is the best in the world. The financial markets are soaring, hitting 71 record highs this year. Biden cut deficit by one third. America doesn't need to be great again. America is great!

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Ruud Delwel
Ruud Delwel@DelwelRuud·
EHA Research Conference in Malaga In March 2025: "Transcriptional control and chromatin alterations in normal and malignant hematopoiesis" Fantastic opportunity for junior investigators to present and discuss their work with young and experienced scientists. Great program!
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European Hematology Association
European Hematology Association@EHA_Hematology·
Congratulations to this year’s CBTH Scholars! Throughout the program, scholars explored a range of topics and were guided by mentors to elevate their projects to new heights. In addition to advancing their own research, they delved deeper into these key areas: 👉 Bayesian Statistics ️👉 Science Communication  👉 Multi-Layered Data Integration 👉 Data Visualization 👉 Proteomics 👉 Epigenetics Would you like to join our next cohort? This free program will open for applications in June 2025! Don’t miss out on this amazing opportunity to elevate your skills in Computational Biology.
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Ruud Delwel
Ruud Delwel@DelwelRuud·
07 October 2024 at 16.00 CET Erasmus Hematology Virtual Lecture. We have: Kellie Machlus, Boston Children’s , with "Unraveling roles for megakaryocytes beyond platelet production through novel model systems" Spread the news! us06web.zoom.us/j/82722159417 @theclotthickens
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RogerMulet
RogerMulet@RogerMulet·
@pmddomingos @mattwridley That's a rather dishonest statement considering the evidence for the lab leak theory is largely circumstantial, and certainly not "overwhelming". Most published articles agree the virus had a natural origin -- are the authors dumb or is it a conspiracy?
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Ruud Delwel
Ruud Delwel@DelwelRuud·
Don't miss it! Erasmus Hematology Virtual lecture 23 September at 16.00 CET with: Alexander Bick, Vander Bilt University, Nashville. Title: "Clonal hematopoiesis: causes, consequences and management" Link: us06web.zoom.us/j/82722159417
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Ruud Delwel
Ruud Delwel@DelwelRuud·
Erasmus Virtual Hematology Lectures starts again on Monday September 2 at 16.00 CET! We have MAXIM PIMKIN from Harvard/Boston with: "Gene-regulatory networks in leukemia maintenance and immune escape". Link: us06web.zoom.us/j/82722159417 Spread the news! @pimkin
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Ruud Delwel
Ruud Delwel@DelwelRuud·
New paper in Cell Reports: STAG2 mutations reshape the cohesin-structured spatial chromatin architecture to drive gene regulation in acute myeloid leukemia doi.org/10.1016/j.celr… Another Regensburg/Rotterdam collaboration! @ClaudiaGebhard @RogerMulet Fischer/Rehli
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RogerMulet
RogerMulet@RogerMulet·
@elonmusk How does one maximize individual freedom by banning abortion? Merit? Republicans regularly ignore the scientific consensus, while embracing unsubstantiated religious beliefs. Their presidential candidate doesn't even have the support of his former cabinet members.
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Elon Musk
Elon Musk@elonmusk·
I believe in an America that maximizes individual freedom and merit. That used to be the Democratic Party, but now the pendulum has swung to the Republican Party.
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Elon Musk
Elon Musk@elonmusk·
My smartest friends, including those living in the San Francisco Bay Area who have been lifelong Dems, are excited about Trump/Vance
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RogerMulet
RogerMulet@RogerMulet·
@spatialweeb @ylecun @beaudjango It's simply untrue that the scientific community supports the lab leak hypothesis, let alone by consensus. Presenting it as a fact when it's not only makes you come across as dishonest.
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Yann LeCun
Yann LeCun@ylecun·
Must have been my tweet in defense of Anthony Fauci. Elon's call for Fauci to be prosecuted and imprisoned is pretty high up on the scale of anti-science assholery. Apparently, mistreating scientists is habit, whether they work for him or not.
Big Tech Alert@BigTechAlert

🚫 @elonmusk is no longer following @ylecun

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Max Jaderberg
Max Jaderberg@maxjaderberg·
Super excited to be releasing AlphaFold 3 today, developed by @IsomorphicLabs and @GoogleDeepMind: our next generation AI model for predicting the biomolecular structures and interactions of proteins, DNA, RNA, small molecules, and more: bit.ly/44yfaCw 1/
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