
RogerMulet
34 posts

RogerMulet
@RogerMulet
NL-based bioinformatician. Interested in epigenetics, leukemia and science in general. I support evidence-based practices.





Excited to share our preprint (@D_Pastoors): "MECOM is a master repressor of myeloid differentiation through dose control of CEBPA in acute myeloid leukemia"! biorxiv.org/content/10.110… MECOM is a TF whose overexpression leads to aggressive AML and with an immature phenotype. [1/15]




The unemployment rate is currently about 4.1%, the lowest since 1968. Inflation is low, at 2.2%. GDP growth is the best in the world. The financial markets are soaring, hitting 71 record highs this year. Biden cut deficit by one third. America doesn't need to be great again. America is great!





Study points to animal origin of Covid-19. Were definite proof, but pretty strong evidence. The whole point of the scientific method is to mimimize the effect of human cognitive biases, preconceived ideas, and prejudice. Scientists make a hypothesis, then collect data to constitute evidence for whether the hypothesis is true or false. One reason for the peer review process in science is to identify methodological flaws in a piece of work. A major characteristic of the process of science is to systematically question claims and see if results can be reproduced or not by different groups than the original authors. The history of science is replete with experiments whose results showed the opposite of what the scientists set out to establish. An example? The 1887 Michelson-Morley experiment attempted to show the existence of the luminiferous aether by measuring differences in the speed of light in various directions due to the motion of the earth. Instead, it showed that the speed of light was constant and independent of the motion of the observer. This was explained theoretically by Einstein's theory of special relativity in 1905 (he used the constancy of the speed of light as a premise).





















