Silas E Busch

186 posts

Silas E Busch

@SI_plasticity

Postdoc @Rockefeller University, UChicago PhD Works on: Dendrites, mouse cerebellum, fly learning+memory Dabbles in: Philosophy, writing, poetry, plants

New York, USA Katılım Eylül 2019

367 Takip Edilen199 Takipçiler

Sabitlenmiş Tweet

Silas E Busch@SI_plasticity·27 Tem

New in @ScienceMagazine In mice, we explore a non-canonical circuit in a sub-population of cerebellar Purkinje cells with dendrite structure motifs that are nearly universal in humans science.org/doi/full/10.11… #ScienceResearch 🔬🐭🧠🧑‍🦱@UChicago_Brains @UChicagoBSD @UChicago 🧵⬇️

English

37.5K

Silas E Busch@SI_plasticity·18 Nis

Huge thanks goes to my mentor Christian Hansel, the UChicago neuro institute @UChicago_Brains, and to many for their ideas and feedback along the way: @TingFengLin1, Abby Silbaugh, @auroraferrell_ , Donald Huang, @EatockLab, Wei Wei, @Sheffield_Lab, @neuroMOOC

English

116

Silas E Busch@SI_plasticity·18 Nis

Purkinje cells of similar morphologies also tended to cluster near each other. If morphology dictates some features of PC function, then this cell-cell clustering may generate patches of functional similarity in the cortex

English

Silas E Busch@SI_plasticity·18 Nis

Inspired by Cajal, the Hansel lab's new work in @eLife provides a comparative histological analysis of human and mouse Purkinje cell morphology. Following our 2023 study, we detail differences of scale and kind between the neurons of the two species 🧵👇 elifesciences.org/articles/105013

English

5.7K

Silas E Busch@SI_plasticity·29 Eyl

I was very excited to speak at the @wusmsl journal club. Great community ! Got some really interesting questions and insights from within and outside the cerebellar field! Check out the recording here

Andrew Pruszynski@andpru

See our first @wusmsl journal club of the academic year! We hosted @SI_plasticity, who told us about this fascinating work, recently published in Science, showing the innervation of purkinje dendrites by multiple climbing fibers. youtu.be/1iH1dvyKXIs

English

789

Silas E Busch@SI_plasticity·12 Eyl

@AmandaLeBel3 Thanks! As you’ll see, some of the analysis and discussion is inspired by your insightful (functional!) work in human 😁

English

Amanda LeBel@AmandaLeBel3·12 Eyl

@SI_plasticity Super excited to read this! Congrats on the new paper!

English

Silas E Busch@SI_plasticity·11 Eyl

Human neurons are incredibly complex and Purkinje cells are, by far, the largest in our brain. We give a detailed characterization of their dendrite and spine morphology and distribution across cerebellar regions compared with mouse. Check it out!

bioRxiv Neuroscience@biorxiv_neursci

Non-allometric expansion and enhanced compartmentalization of Purkinje cell dendrites in the human cerebellum biorxiv.org/cgi/content/sh… #biorxiv_neursci

English

5.5K

Silas E Busch@SI_plasticity·11 Eyl

@carobellum What’s more, parts of this would absolutely not exist if not for your studies!! I’m so grateful for your work and insight!

English

Caroline Nettekoven 🧠@carobellum·11 Eyl

Great new work from @SI_plasticity on human Purkinje cell diversity! Had the pleasure of giving it an early read and it’s another Tour de force 🙌

Silas E Busch@SI_plasticity

English

759

Silas E Busch@SI_plasticity·11 Eyl

@neurodevKathy @aniladmello Thank you! Do let me know if you have thoughts you’d like to share; I’d love to get your perspective on it!

English

109

Silas E Busch@SI_plasticity·5 Eyl

@carobellum @UniofOxford @wellcometrust @MKFlugge Incredible news! Congratulations Caro!! I’m glad they recognized how awesome you are!! 🤩🥳

English

147

Caroline Nettekoven 🧠@carobellum·4 Eyl

I'm still in shock, but so excited to return to @UniofOxford next year with a @wellcometrust Early Career Award. Here is to five years of cerebellar ultrasound research with @MKFlugge and my other stellar collaborators! Thank you to everyone who helped me on the way. 🥳🎉🧠 x.com/WesternuWIN/st…

English

154

9.7K

Silas E Busch@SI_plasticity·12 Tem

@HeatherDSnell I’m dying 🤣

English

Heather Snell, PhD@HeatherDSnell·12 Tem

Omg! I went back to Amazon to see how I could have ordered such a large wrench. There are multiple options in size. I got the 18" one. Y'all there's a 24" version and look at this review!!!

English

598

Heather Snell, PhD@HeatherDSnell·10 Tem

Funny #newpi ordering moment: needed a larger wrench to tighten our regulators for our gas tanks. Bought a "large wrench". It's 5.2 lbs of solid steel! Normal sized wrench (pic 1) is what I was going for. Bonus: it doubles as blunt force object! P100 tip box for size reference.

English

5.6K

Silas E Busch@SI_plasticity·5 Şub

@thejenjay Oh sweet! Nice way to spread out the thesis writing process. Best of luck!!

English

Jennifer Jahncke@thejenjay·5 Şub

@SI_plasticity We were invited to write a lit review on my concentration a couple years ago and I’m just using that as my intro 😎 very thankful I don’t have to face that again 😂

English

Jennifer Jahncke@thejenjay·5 Şub

Writing my discussion chapter

English

925

Silas E Busch@SI_plasticity·20 Oca

@thejenjay Incredible (scientifically and artistically)!!

English

123

Jennifer Jahncke@thejenjay·19 Oca

I'm back with some more images of sparsely labeled cerebellar molecular layer interneurons ✨🧠🔬

English

381

34.6K

Silas E Busch@SI_plasticity·8 Ara

@neurodevKathy Thank you!

English

Silas E Busch@SI_plasticity·1 Ara

Check out this wonderful write-up by #NIH Director's Blog on my image and our recent work in mouse and human cerebellum!

NIH@NIH

Learn how this winning image in the NIH #BRAINInitiative’s annual photo/video contest is changing conventional wisdom on #brain anatomy. Details on the #NIH Director’s Blog. #studyBRAIN go.nih.gov/VMP5QWb

English

525

Silas E Busch@SI_plasticity·1 Ara

The photo is now part of the 2024 BRAIN Initiative calendar, which you may have picked up from the #NINDS booth at SfN or can order. catalog.ninds.nih.gov/publications/2…

English

123

Silas E Busch@SI_plasticity·1 Ara

The #NIH Director's Blog wrote an awesome piece about my submission to the @USBrainAlliance photo contest and how it encapsulates my recent work comparing mouse and human cerebellar anatomy. #studyBRAIN directorsblog.nih.gov/2023/11/28/the…

English

261

Keşfet

@UChicago_Brains @TingFengLin1 @EatockLab @Sheffield_Lab @neuroMOOC @eLife @wusmsl @AmandaLeBel3