Sam Williams

TWO postdoc positions in Computational Microbiology and/or biochemistry. Join our interdisciplinary group in the new Life and Mind Building @OxfordBiology, @UniofOxford, @IneosOxford Please apply and share this post: jobs.ac.uk/job/DMP641/pos…

antiSMASH 8.0 is here. Enjoy analysing gene clusters, chemistry, enzymes, regulation etc with improved capabilities. academic.oup.com/nar/article/do…

4/4 Thanks to my new colleagues David Faurdal and Tue Sparholt Jørgensen for helping me resolve the tricky terminal inverted repeats in Streptomyces sp. NL15-2K

3/4 Given the fragmented nature of the BGCs containing these diels-alderases we resequenced both strains. We hope these talented strains are useful for #genomemining. Especially as this is only the 4th complete genome from the incredibly gifted and underexplored Kutzneria genus.

2/4 We identified rare diels alderase enzymes, capable of stereoselective C-C cycloadditions, from the scaffold assemblies of these strains. We also successfully characterised in vitro activity of the 'Cyclase15' from NL15-2K here: …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cb…

1/4 📢Now published in @ASMicrobiology #MRA! Complete genomes of two actinomycetes containing abyssomicin-like gene clusters: #Kutzneria buriramensis DSM 45791 and #Streptomyces sp. NL15-2K #secmet #microsky journals.asm.org/doi/10.1128/mr…

Wow! What on earth happened here? (I don't mean "why did so many people move to a different social network," but "why did they all go to 🦋")

While I will keep this account I am now also on blue sky as many scientists are moving over and want to keep up to date on the most recent discoveries. Can find me as pieterdorrestein

I knew there were a lot of fake accounts on this platform, but they are usually obvious. I had no idea how intricate and complex the ruse could be. Get a load of this story. 1/

All too often researchers use non-standard methods and so MIC data cannot be reproduced. To reduce that error read this: ‘Antibiotic susceptibility testing using minimum inhibitory concentration (MIC) assays’ ⁦⁦⁦@bondSSbond⁩ nature.com/articles/s4425…

PhD positions in Chemical Biology starting Sept 2025 in our new labs at Imperial College, in the centre of West London’s expanding Innovation District. @imperialcollege, @impchemistry, @ImpScience, @WCIDLondon. Deadline 18 Nov 2024. More details here: jobs.ac.uk/job/DKN054/phd…

@DavidRcoMark Congrats mate!

Very glad this is out 🥳

Our group is moving to Imperial College from 1 Dec 2024. We are super excited to be joining @impchemistry, @imperialcollege, with new labs in the Molecular Sciences Research Hub at the centre of West London’s buzzing Innovation District @WCIDLondon.

Invasive fungal infections kill 3.8 millions of deaths annually. Current antifungal medicines are limited by toxicity, drug-drug interactions and resistance. We report alligamycin as a novel antifungal lead against resistant Aspergillus and Talaromyces. nature.com/articles/s4146…

Humans tend to underestimate the pace of innovation and overestimate the inertia of incumbent technologies. Clean energy technologies have scaled much more rapidly than predicted by modellers.

We are pleased to announce our upcoming mzmine webinar series in collaboration with VMOL. This series will focus on various aspects of mass spectrometry data processing, showcasing the capabilities of mzmine. Sign up for free!

My 2-week visit to the @uni_tue is coming to an end Thanks to my incredible host @EviStegmann and fingers crossed the 83 extractions I'm taking back to CPH contain that peak I'm hunting🔎

🚨 Job Alert - 2 year Postdoc 🚨 Somayah Elsayed and myself seek an enthousiastic candidate for a two year postdoctoral position in the topic of Ribosomally synthesized and post-translationally modified peptides (RiPPs)! 😎 For more information see 👇 linkedin.com/posts/jjjvande…

What kind of childhood makes a top scientist? Is it enough to have all the right traits (brilliance, grit, etc) or do you need the right family too? And why should we care? A 🧵 on our paper on the Nobel Laureates. A teaser: the income distribution of the laureates' fathers.1/N

This is the moment Ratcliffe power station came off the electricity system for the final time, marking the end of 142 years of coal generating electricity in Great Britain!