
Sarah Cai
297 posts

Sarah Cai
@SarahWCai
PhD @RockefellerUniv in the de Lange + Walz labs | structural biology and biochemistry | 2024 @SchmidtFellows | @Caltech ‘18 | she/her | views my own




Excited to share that I'm starting a new research group at @uclachem and @cnsiatucla! We'll focus on the molecular architecture of tight junctions - barriers crucial for human health - using biochemical reconstitution, cryo-EM, X-ray crystallography, and cell-based assays.








Our Spotlight on beautiful work from the de Lange (@SarahWCai et al), Walz, and Cech labs. At the end, it is POT1 again: Phosphorylation allows human telomeric protein POT1 to recruit the C-rich strand end replication machinery: Molecular Cell cell.com/molecular-cell…



Our review on using single-molecule correlative force and fluorescence microscopy to study protein-DNA interactions is out! Honored to share our perspective on this fast-growing field. Thanks to @AnnualReviews for the open access volume 👍🏼 doi.org/10.1146/annure… @BadAtCloning

Congratulations to Qixiang He (@QixiangHe), who was awarded a Louis and Elsa Thomsen Wisconsin Distinguished Graduate Fellowship! biochem.wisc.edu/2024/07/12/qix… @cijilim @UWMadisonCALS @UWMadBiophysics





