Sardiello Lab

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Sardiello Lab

Sardiello Lab

@SardielloLab

Washington University in St. Louis. Main topics: lysosomal and mitochondrial biogenesis, neurodegenerative diseases, TFEB.

St. Louis, MO Katılım Şubat 2017
179 Takip Edilen241 Takipçiler
Sardiello Lab
Sardiello Lab@SardielloLab·
Amazing work from the @ZhandongLiu lab! Coexpression enrichment analysis at the single-cell level reveals convergent defects in neural progenitor cells and their cell-type transitions in neurodevelopmental disorders genome.cshlp.org/cgi/content/lo…
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Sardiello Lab
Sardiello Lab@SardielloLab·
The Sardiello lab has just moved to Washington University in St. Louis. Contact us if interested to join as a post-doc, computer scientist, or lab manager/technician.
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Sardiello Lab retweetledi
From the Labs at Baylor College of Medicine
From the Labs at Baylor College of Medicine@BCMFromtheLabs·
Congratulations @lakshyabajaj5 @SardielloLab et al for solving the #CLN6 puzzle in #BattenDisease! @jclinicalinvest @bcmhouston @TCHResearchNews
Lakshya Bajaj@bajajlab

Super stoked to finally see my graduate school paper out today in @jclinicalinvest. We show that a CLN6-CLN8 complex (that we refer to as EGRESS: ER-to-Golgi relaying of enzymes of the lysosomal system), recruits lysosomal enzymes at the ER to promote their Golgi transfer.

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Lakshya Bajaj
Lakshya Bajaj@bajajlab·
Super stoked to finally see my graduate school paper out today in @jclinicalinvest. We show that a CLN6-CLN8 complex (that we refer to as EGRESS: ER-to-Golgi relaying of enzymes of the lysosomal system), recruits lysosomal enzymes at the ER to promote their Golgi transfer.
From the Labs at Baylor College of Medicine@BCMFromtheLabs

Dr. M Sardiello @SardielloLab, Dr. L. Bajaj et al reveal in @jclinicalinvest how #CLN6 can cause #BattenDisease @bcmhouston @TCHResearchNews jci.org/articles/view/…

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Sardiello Lab
Sardiello Lab@SardielloLab·
Our new article showing that CLN6 and CLN8 are obligate partners in the recruitment of lysosomal enzymes in the endoplasmic reticulum for Golgi transfer jci.org/articles/view/…
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Sardiello Lab
Sardiello Lab@SardielloLab·
Check out our new PNAS paper showing mTORC1-independent lysosomal depletion and abnormal glycogen storage in tuberous sclerosis pnas.org/content/early/…
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Sardiello Lab
Sardiello Lab@SardielloLab·
Dr. Paul Luzio's commentary on our article "CLN8 is an endoplasmic reticulum cargo receptor that regulates lysosome biogenesis" doi.org/10.1038/s41556…
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Keşfet

@JaiSharma__ @HastingsLab @ZhandongLiu @LeventalLab @Stephane_MTL @LakshyaBajaj5 @jclinicalinvest @bcmhouston