Lakshya Bajaj

I am delighted to share with you all that I have joined the University of Puerto Rico, School of Medicine as an Assistant Professor. Our lab plans to study Neurogenesis and Neurodegenerative disorders from the perspective of Ribostasis and Proteostasis. bajaj-lab.com

RNA-protein interactions were once thought to be undruggable 💊🔬In our latest study, we show how the FDA-approved drug Eltrombopag disrupts HuR/RNA interactions, altering protein levels, iron metabolism, and hormone pathways 🧬 #RNA #DrugDiscovery bmcbiol.biomedcentral.com/articles/10.11…

A novel lncRNA FAM151B-DT regulates autophagy and degradation of aggregation prone proteins: medrxiv.org/content/10.110…

@elonmusk And this guys wants to make our species interplanetary!! LOL

Globalism is civilizational suicide

Wow. A bishop just called out Trump and Vance to their faces at church. “The vast majority of immigrants are not criminals. May I ask you to have mercy, Mr. President, on those whose children fear their parents will be taken away.”

Barbara McClintock's discoveries on genetics were so far beyond the understanding of the time that other scientists ignored her work for more than a decade. But she trusted her evidence and persisted. Watch the very moment she received the medicine prize in 1983. #NobelPrize

The body's self-cleaning mechanism that recycles old proteins requires spermidine, a remarkable molecule that prevents hair loss in mice and extends the lifespan of every species tested So what is spermidine and does it work in humans? 🧵

The Human Microglia Atlas (HuMicA) unravels changes in disease-associated microglia subsets across neurodegenerative conditions nature.com/articles/s4146…

Interested in joining our growing interdisciplinary team studying viruses, RNA, and condensates? Looking for a postdoctoral position? Please consider joining us in Cambridge, UK, or drop us a line to discuss these opportunities: jobs.cam.ac.uk/job/49901/

The Genome India Project offers us 10,000 genomes that represent the 4 broad linguistic groups, and regions across India incl tribal populations. They are available at the Indian Biological Data Centre at RCB, Faridabad for academics to analyze and unveil mysteries held in them.

Chemicals derived from neurotransmitter molecules in the brain can act as epigenetic marks on histone proteins to regulate gene expression. These marks control circadian clock genes and influence behaviour go.nature.com/3DLWE0a

Cholesterol deficiency directs autophagy-dependent secretion of extracellular vesicles biorxiv.org/content/10.110…

The molecular mechanism of temperature-dependent phase separation of heat shock factor 1: nature.com/articles/s4158…

5,562 proteins were found to have tissue-specific enrichment across 32 human tissues. ◼️ The majority of them (3,088) are enriched at the protein but not RNA level. 🧠 The brain hosts the largest number of proteins that are only enriched at the protein level but not RNA level.

@LiWang_neuro @Nature Congratulations Li... great job!

Brain cancer leverages the same tools as the developing brain 🧠! In our new study, published today in @Nature, we mapped neocortical development to explore brain cancer and neuropsychiatric risks. #stemcells #brainresearch nature.com/articles/s4158…

Canadian politicians are now threatening to take California, Washington and Oregon, promising them free healthcare if they join as a province of Canada

Aberrant splicing in Huntington’s disease accompanies disrupted TDP-43 activity and altered m6A RNA modification: nature.com/articles/s4159…

mRNA export factors store nascent transcripts within nuclear speckles as an adaptive response to transient global inhibition of transcription dlvr.it/THBpGy

Check out this study from @JamesAOo7 et al. revealing how trans-acting lncRNAs target SWI/SNF complex to lineage-specific enhancers to maintain open chromatin: nature.com/articles/s4146… Congrats @JamesAOo7 @tim_warwick Matthias S. Leisegang and the rest of the authors

Transposon exonization generates new protein-coding sequences dlvr.it/THBv6S