Mihir B. Doshi

Our paper has been published today in Nature Metabolism! I extend my sincere thanks to all authors: @SungJin2619, @MikeLangePhD , T. Tseyang, @ScienceGraduate, T.Y. Kim, Y. Song, D.I. Kim, @Greer_Lab , @OlzmannLab , @JBSpinelli , and Dohoon Kim. #auth-Namgyu-Lee-Aff1-Aff2" target="_blank" rel="nofollow noopener">nature.com/articles/s4225…

“It’s like clogging a drain.” Dohoon Kim, PhD, & colleagues have found a way to poison cancer cells with their waste: direc.to/khqL As published in @Nature. #LungCancer @UMassChanMCCB @UMassCancerCtr @ScienceGraduate @JBSpinelli @KarlSimin @lab_mercurio @MarianWalhout

@hirenj @Nature @NamgyuLee1 @chrashwood @KarlSimin @cholsoon_jang @lab_mercurio @MarianWalhout @JBSpinelli It is also theoretically possible that aberrant UGT mediates aberrant glucuronidations contributing to toxicity but we did not see any evidence. 2/2

@hirenj @Nature @NamgyuLee1 @chrashwood @KarlSimin @cholsoon_jang @lab_mercurio @MarianWalhout @JBSpinelli Hi Hiren, that is an excellent point. Regarding UGTs, we've thought about them but have not looked extensively. They do not seem to comprise a significant 'sink' that consumes the aberrant accumulation of UDPGA. 1/2

I'm incredibly thrilled to announce my first-author publication in @Nature . I would like to thank all my collaborators and specially @NamgyuLee1 , @chrashwood , @KarlSimin , @cholsoon_jang , @lab_mercurio , @MarianWalhout, @JBSpinelli my PI and Dohoon Kim.

The Senate passed the Sunshine Protection Act which would make daylight saving time permanent across the U.S. beginning in 2023. n.pr/3u0QWir

Great! reuters.com/article/health…

.@eric_lander says he’s seen the U.S. take on “amazing challenges” to make the world a better place. Now, he says, “the opportunities we have and the challenges we face are greater than ever before” cbsn.ws/2KjDqUa

“It's the gaps, stupid!" Despite the dogma police, we’re not completely broken, just like the DNA: a new model for BRCAness tinyurl.com/BRCAness from phenom student Nick Panzarino in Cantor Lab.tinyurl.com/Cantorlab

BREAKING NEWS: The 2020 #NobelPrize in Chemistry has been awarded to Emmanuelle Charpentier and Jennifer A. Doudna “for the development of a method for genome editing.”

Hello SciTwitter, I am proud to share ANOTHER paper out of the Kim Lab today-this time a great review written by my good friends and lab mates @NamgyuLee1 and Meghan, and myself in a supporting role, and advised by Do. Congrats again Kim Lab!🎉 Read here: rdcu.be/b5PaO

Selenium metabolism protects them against ferroptotic insults, but a toxic intermediate formed in this process can be exploited to poison them. Congratulations co-first authors @A_Carlisle_19 , Namgyu Lee and Kim lab. @NatMetabolism Read here: rdcu.be/b5r2w (2/2)

Selenium is a micronutrient that is incorporated into selenoproteins via the selenocysteine biosynthesis pathway. The authors describe a two-faced role for selenium in cancer cells (1/2)

Online now! A micronutrient with major effects on cancer cell viability dlvr.it/Rb482k

Today I celebrate the publication of the research paper I have worked hard to develop for the past 4 years. Next up, thesis defense- PhD here I come! Most importantly: I could not have done this without my family, friends, and lab mates. Congratulations, Kim Lab! 🎉🎉🎉

@LizRidesBikes Good luck Liz

🚨BREAKING: preliminary data from an ongoing clinical study of #remdesivir showed that in 113 patients with severe #COVID19: ▶️Fever/symptoms rapidly improved ▶️Most discharged within 6 days ▶️2 died (1.8%), much less than expected for severe #COVID19 statnews.com/2020/04/16/ear…

757 people died. Today. In New York City. People, stay at home!

As expected, data emerges to explain observations of #COVID19 “reinfection”—here, most patients who were ”redetected positive” were actually never truly negative. Plus reinfection cannot be rampant if family members living together successively infect each other but all recover.