Special thanks to our collaborators @NVastenhouw and Darren Gilmour labs for all the critical feedback, and to @snsf_ch and @EMBO for funding support that made this work possible 🥂
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Shayan Shamipour
808 posts
Shayan Shamipour
@ShamipourShayan
@SNSF_ch Ambizione junior group leader @UZH_en, studying principles controlling development | @EMBOfellows postdoc @pelkmanslab | PhD @HeisenbergCPLab
Katılım Ekim 2017
484 Takip Edilen494 Takipçiler
Altogether, 3D-4i enables systematic analysis of molecular and spatial heterogeneity across scales, providing a new framework for understanding how coordinated regulation emerges in complex multicellular systems. 🌱💡
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Very happy to share our latest work extending iterative immunofluorescence to in toto imaging of early zebrafish embryos (3D-4i), integrated with a 3D-dedicated analysis pipeline! 🐟🔬📊Kudos to Max Hess for this PhD milestone💪@pelkmanslab shorturl.at/cO0u7
Let's zoom in!
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@ShamipourShayan @lucaspelkmans @pelkmanslab @UZH_en Congrats Shayan, Lucas and the team! Exciting work!
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Shayan Shamipour retweetledi
Now out in its final form, with a new title "Mechanical control of cell fate decisions in the skin epidermis" and simulations/quantifications! See below for thread of how unbalanced tensions can bias fate choices in minimal 3D models of tissues/tumors! nature.com/articles/s4146…
Edouard Hannezo@EdouardHannezo
Happy to share the latest work from @DrPreetiSahuPhD, with @ASanchezDanes on the biomechanics of cell fate choices during tumor initiation! We implement/test a 3D vertex model with proliferation and fate choices for multilayered tissues! 🧵below (1/n) bit.ly/3ZXxJzk
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📣 Symposium 2050 at the University of Zurich
Join us for this event exploring emerging directions in life sciences, presented by a diverse group of leading experts.
Free and open to all! More info/register:
ema.uzh.ch/RTTHF
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Shayan Shamipour retweetledi
You think revolving around yourself makes you grow? That’s not necessarily true for the #development of #Drosophila #EggChambers - check out our recent collaborative work with the Dahmann lab. journals.biologists.com/dev/article/15… . Congrats to Akanksha Bhatt and Valentin Ruffine 👏🥳
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Shayan Shamipour retweetledi
Happy to share the latest work from @DrPreetiSahuPhD, with @ASanchezDanes on the biomechanics of cell fate choices during tumor initiation! We implement/test a 3D vertex model with proliferation and fate choices for multilayered tissues! 🧵below (1/n) bit.ly/3ZXxJzk
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Shayan Shamipour retweetledi
New paper alert!
Amazing grad students @levy_ezra and Isabella Leite live image female germline cyst formation in embryonic gonads of mice and discover that even as these structures form, through divisions with incomplete cytokinesis, germ cells are incredibly motile.
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Shayan Shamipour retweetledi
Congratulations to Dr. Victoria Deneke (@deneke_v), Andreas Blaha, and the @PauliGroup, on their @CellCellPress paper!
They used #AlphaFold to investigate fertilization in vertebrates.
🎧 Episode with discussion: bit.ly/4f30gJ1
🧵: x.com/deneke_v/statu…
Victoria Deneke@deneke_v
The life of each one of us began when a sperm and an egg came together. But what actually happens at a molecular level? Our latest work @PauliGroup @CellPress reveals a conserved fertilization complex that bridges sperm and egg in vertebrates! (1/8) cell.com/cell/fulltext/…
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Shayan Shamipour retweetledi
If you didn't yet have enough good reasons to share your bioimage data, Matthew (@BioimageA), Josh (@notjustmoore), Erin (@tuesdaystitches), Assaf (@AssafZaritsky) and I are here with squirrel drawings to convince you that you should do it:
journals.biologists.com/jcs/article/13…
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Shayan Shamipour retweetledi
‘Be water my friend’
Intercellular fluid dynamics in tissue morphogenesis @CurrentBiology with @maitrejl and @Descroix16, we are happy to present you our new review: doi.org/10.1016/j.cub.…
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Shayan Shamipour retweetledi
👩🔬Curious about #fertilisation and #development? Join Andrea Pauli’s group through the Vienna BioCenter #PhD Program (@TrainingVbc)!
⏳ Deadline: Today! 🚨
Apply now: training.vbc.ac.at/phd-program/
📽️Watch Andi's 'Scientist Snapshot': youtube.com/watch?v=X9FN8v…
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Shayan Shamipour retweetledi
Seems like ages ago! Our story is now published in Science. Don't read the quoted post, check-out the published paper instead: science.org/doi/10.1126/sc… 🥳 🥳 🥳
Dimitri Fabrèges@DimitriFabreges
Stochasticity controls robustness in embryogenesis. Although it may sound counterintuitive, this is one of the conclusions we defend in our preprint "Temporal variability and cell mechanics control robustness in mammalian embryogenesis" (bioRχiv: biorxiv.org/content/10.110…).
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Shayan Shamipour retweetledi
📢 Check out our @teamstembryo @NatureCellBio News & Views with postdoc @alex_schauer_ on the latest feat in human stem-cell-based embryo models by @Nobu_Hamazaki, @JShendure & colleagues. Full text: rdcu.be/dWw3c nature.com/articles/s4155… #gastruloids
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Shayan Shamipour retweetledi
Hello everyone, excited to share our preprint: biorxiv.org/content/10.110…
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Everyday, cells like this crawl through your body to protect you. While we know that their front 🔴 and back 🔵 polarity programs work together, how exactly do these two processes communicate? Lets chat!
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