Sigman Lab

Check out this great work by @DalmauDavid! 📊📈

Check out this great opportunity by our friends in @TheAlegreGroup and consider signing up!

In our latest featured article, Haas, Hardy, Sowndarya, Adams, Coley, Paton and Sigman demonstrate that descriptors for compounds can be predicted on-the-fly at a high degree of accuracy by using DFT-level libraries as training data for a GNN. Read more: doi.org/10.1039/D4DD00…

We’re excited to share our quantitative assessment of the potential impact of skeletal edits, now on ChemRxiv! This cheminformatic platform was developed with @lucaskaras1 from @Sigman_Lab and Reilly Eason & @Charles_chem at #MerckChemistry. tinyurl.com/yc4jev9k

Friday we celebrated @MoeSamha7 who brilliantly defended his PhD thesis. Congrats Dr Samha, we look forward to seeing your future successes!

Check out the final version of ROBERT, a great tool to automate some ML tasks! Congrats to the @TheAlegreGroup and especially @DalmauDavid, who’s currently visiting us in Salt Lake City.

Increasing catalyst lability to tame a spirited metal: chemrxiv.org/engage/chemrxi… A fun and insightful collaboration with @Sigman_Lab and Gschwind group (@ChemistryKoenig, @IndrajitGhosh85, @JamieCadge).

Our semiannual meeting series kicked off yesterday and was a great success. Next week's meeting will again feature presentations on the exciting work being done by C-CAS members. If you haven't already registered, you may do so here: docs.google.com/forms/d/e/1FAI…

Development of a Deactivation-Resistant Dialkylbiarylphosphine Ligand for Pd-Catalyzed Arylation of Secondary Amines | JACS @Sigman_Lab @UUtah @UtahChemistry @MIT @ChemistryMIT @BuchwildGroup @TotalSyntheses #Phosphine #Pd #Arylation #Amines pubs.acs.org/doi/10.1021/ja…

RT. Chemistry and data junkies—honk if you want to join our team as prestigious Azrieli Postdoctoral Scholars and work at the interface of catalysis, machine learning, and uncensored mechanistic bliss. Deadline 18 Nov 2024 azrielifoundation.org/wp-content/upl…

Our work in @SarpongGroup on remodeling of 2-pyrones to aryl amines under mild conditions is out in @ChemicalScience. I enjoyed working with Louis in @bobbypaton’s lab and Melissa in @Sigman_Lab to better understand this unexpected transformation! 1/3 pubs.rsc.org/en/Content/Art…

Thanks Matt @Sigman_Lab for a truly inspiring talk @DCBPunibern and for a great evening with @albrecht_lab Looking forward to the next catch up!

Congrats to fifth year grad student @MoeSamha7 for winning the best oral presentation prize at the “Accelerating catalytic advancements thorough the precision of HTE & calculation” symposium #ACSFall2024 Great work as always! 👏🏻🦾

This week, Vern represented the Sigman group graduate students at the Stereochemistry #GRC and brilliantly presented her work!

Current and past Sigman group representing at stereochemistry grc with a special guest @JacobsenLab

I’m currently at my first ever conference- @GordonConf Stereochemistry- and I’m so blown away by how supportive all the wonderful chemists are here! I can’t believe I’m so fortunate to be able to talk about how cool the universe is for a JOB! Huge fan of asymmetric catalysis.

Natalie, Moe, and Simone have been presenting their work at the Organic Reactions and Processes #GRCORP. Lots of data science for reaction optimisation, well done!

Past and present Sigman group members at the Organic Reactions and Processes GRC. Always a pleasure catching up with Sean and Anat @anatmilo!

Throwback to Alex and Avijit presenting their work in collaboration with Will from the Reisman Lab at the CSEO meeting in Caltech a couple of weeks ago. Really exciting science coming soon!

Last night Natalie delivered a great presentation on her work merging HTE and data science at the Organic Reactions and Processes GRS. Well done!