Sima Dubnov

🧵1/9 How do we extract signal-specific information from single-cell data? In our new #CellSystems paper, we introduce bioIB - a method for signal-aware, biologically interpretable compression. With @zoe_piran, Amit Alper, Adi Yefroimsky, Hermona Soreq, supervised by @mor_nitzan

1/7 How are cells spatially reorganized between conditions in tissues? Introducing CASEI: a method for inferring condition-associated spatial phenotypes in spatial omics data. w/ Roy Friedman (friedmanroy.github.io) & @mor_nitzan biorxiv.org/content/10.648…

9/9 Check it out! Paper ➡️ cell.com/cell-systems/a… Tutorials ➡️ github.com/nitzanlab/bioIB

8/9 We further demonstrate bioIB in epithelial-to-mesenchymal transition and immune development, uncovering signal-specific gene programs and transitions.

🧵1/9 How do we extract signal-specific information from single-cell data? In our new #CellSystems paper, we introduce bioIB - a method for signal-aware, biologically interpretable compression. With @zoe_piran, Amit Alper, Adi Yefroimsky, Hermona Soreq, supervised by @mor_nitzan

מכון ויצמן התקבל בוואצאפ, אתן קרדיט אם יהיה

Our lab at the Weizmann Institute was hit tonight by Iran We will rebuild and return 💪

6/ P.S. BrainFREEZE was inspired by the fantastic @nightsciencepod. Can’t recommend it enough! 🎧

5/ Sharing what we don’t know is just as important as sharing our wins. It helps us beat frustration and opens the door to real discoveries. Let’s make academia more honest—and more human—by talking about failure. Share your BrainFREEZE! 🧠❄️

To succeed in science, we must learn to fail. Big discoveries often come from getting comfortable with failure — but no one teaches grad students how to do that. Why don’t we talk more about failure in science? It’s time we start. 🧵

In today's episode of the Night Science Podcast we talk with Martin Schwartz from @Yale about the importance of stupidity in science: while learning science makes you feel smart, true scientific discovery often involves feeling stupid, because it means venturing into the unknown.