Simon Cox

Associations and interactions between premorbid cognitive health, apolipoprotein e4 genotype, and incident Alzheimer’s disease in @uk_biobank 🧠🧬 Open access paper: nature.com/articles/s4440… Feat @SimonRCox @WillStewNeuro @JosieNeuro @DrTerryQuinn et al 2.5-min explainer...

Do you… do you see what you did there…?

it’s so funny to see ml people read these advancements. they think it’s like a YOLO v7 released, you can just plug and play. welcome to the thunder dome. we still can’t reverse hair loss or get rid of wrinkles or make pills that make you sleep well. forget brain transplants.

We're celebrating the International Day of Women and Girls in Science #February11 As #Womeninscience, we have the opportunity to shape research on #cognitive #ageing, influence policies that promote healthy ageing, and support future generations of women in #STEM. @SchoolofPPLS

This new paper should have made global headlines along the lines of "Geneticists warn next battle may be against an army of IQ 170 people, 7-feet tall, and free from all mental & physical disease (or else end the species in an unintended genetic meltdown)". Instead it dropped without a murmur. The reason, curiously, lies in the review history (which is online but easily overlooked)… Reviewers criticised use of examples based on gene editing for IQ, along with other examples discussing height and weight, which were deemed stigmatizing. Removing all mention of these polygenic traits, the final paper keeps a laser focus on severe disease such as Schizophrenia, and tabulating the known ethical dilemmas of gene editing. But what did they find In the initial draft?

One week left to apply for this exciting @PrecisionMedPhD PhD project examining the links between pain prescribing and cognitive decline. Application deadline: 13th January. Get in touch if you have any questions! 💊🧠

EPIC new piece of work led by the inimitable @JoannaMoodie + PACKED supplement + new brain maps.

🌟PhD Opportunity🌟 Investigate the links between opioids, other analgesics, and cognitive decline and dementia. Supervised by myself, @SimonRCox, @MarioniGroup, @HaggSara, & @BarbNicholl. Learn more about our @PrecisionMedPhD project and apply below!⬇️ usher.ed.ac.uk/precision-medi…

🧠🧬New preprint! Lifetime brain atrophy GWAS (N = 43,110). A thread Lifetime brain atrophy estimated from a single MRI: measurement characteristics and genome-wide correlates | bioRxiv

“Lessons we learned from the Lothian Birth Cohorts of 1921 and 1936”: edin.ac/3YMksHV A new review of the main LBC findings on #brain and #cognitive #ageing (and much more!) by the founding and current Directors of the LBC1921 and LBC1936 Ian Deary and @SimonRCox

📢I am the first author alert! In this review, we found consistent functional, limited structural, and promising microstructural evidence fro APOEe4-related vulnerability in the brain. Have a read and share with your network! ✨ sciencedirect.com/science/articl…

It took me SEVEN years to figure out that you can save a ggplot as a vectorized .svg file ggsave("file.svg"). The svg file can be opened on powerpoint and it will be completely vectorized, even text are still recognized as text boxes! No more recreating plots on illustrator!!!!!

For only $143, Elsevier/Springer will send me a PDF of my accepted paper that I can share with 25 people :). Publishers again adding tremendous value. I wouldn't know what to do without this attractive option.

@hisotalus You really gotta watch out for those questionable clouds.

If you are nearby Oslo, you would not miss Anders M. Dale's lecture on the occasion of his honorary doctorate at UiO: Computing a lifetime - brain imaging, physiology and genetics. sv.uio.no/psi/english/re…

Congratulations to the UK DRI's @TSpiresJones for receiving the Inge Grundke-Iqbal Award from @alzassociation at #AAIC24! 👏 This award is presented to the senior author of the most impactful study published in Alzheimer’s research in the past 2 years👉buff.ly/3WK21Uz

Really impressive and meticulous paper led by Dr Jo Moodie out now, bringing us closer to understanding how the brain supports our most complex cognitive functions.

A true paper of firsts: first PhD rotation, first paper, first author! Thanks Michelle @drmluciano for your help & support throughout, very happy to see this finally out in the world 🎉

We're delighted to announce the 2024 project awards of the Alzheimer Scotland Student Research Programme: 🟣Neurostructural underpinnings of TBI dementia association 🟣Preparing Scottish dementia services for future diagnostic technologies Learn more 👇 sdrc.scot/news

New paper. We report conventional MRI features and incidental findings from a research cohort of 288 neonates enriched for preterm birth: fn.bmj.com/content/early/… 1/5