Dominic Smiraglia
990 posts

Dominic Smiraglia
@SmiragliaLab
The SmiragliaLab studies cancer epigenetics with the idea in mind that epigenetic modifications provide an exceptional route for cancer cell ‘evolution’ .
Roswell Park Cancer Institute Katılım Nisan 2017
271 Takip Edilen237 Takipçiler

@JeremyWGR @DelReid Love that perspective. I think Vanek is the last jersey I have. My whole family has Tuch, and I will too as soon as he signs a contract with us. I love Benson, but I hate the RAT label. He is so much better than that. He plays super hard, but not anymore dirty than the next guy.
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@DelReid I find it easy to turn it into “I want my kids to know who I respect”
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@TheChargingBUF I couldn’t agree more. This gambling partnership, plus how the MSG broadcast promotes gambling, is gross. If people want to gamble on all sorts of aspects of the game, go for it and enjoy! Leave it out of my sporting event.
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The Sabres not hosting away game watch parties at Canalside - and instead at a casino in Niagara Falls is just so bad and out of touch.
Hopefully the sponsorship deal was worth it because nobody wants this.
Buffalo Sabres@BuffaloSabres
We've got your Game 3 plans all taken care of at @SenecaCasinos! 🔹 Giveaways 🔹 Sabretooth 🔹 Drink specials 🔹 Attendees must be 21+ Learn more → bufsabres.co/41KNhqp
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@cynicalpainmd @CMDeDominicis THIS!!! 1000 times! Ffs….what are we even doing here. Offsides challenge is an abomination to hockey.
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@CMDeDominicis If you need a nasa physicist to determine that it’s offside, then it probably isn’t a big deal. The point of the rule is to prevent players from cherry picking, not to obsess over a millionth of an inch
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@23sabres Jack Quinn. Been loving his game. Driving offense.
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@TageForHart Coz was really good last night. He didn’t ever look like that with us his last 1.5 seasons with us. Glad to see him bounce back, but I am happy with the trade.
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THIS is why I get annoyed with the bandwagon fans who just started watching again this year. Cozens last couple seasons here he had quit and mailed it in. He needed a fresh start. Easy to look at one game and make a decision when you weren’t here for the background of it #Sabrehood
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@SalSports Late 70s-early 80’s. I was young and had to go to bed during playoff games against the Islanders multiple years. I listen to the game on a transistor radio under my pillow. I just remember Billy Smith hacking, slashing, and fighting. Sabres kept losing to them and I hated Smith!
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Dominic Smiraglia retweetledi

@TheMaineWonk Because mail in votes are immune from electronic manipulation?
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‼️ Let’s talk about MAGA wanting to restrict mail ballots: It’s unamerican and will backfire on Republicans
Rural voters are hit hardest by mail ballot restrictions because they face far fewer polling places (median ~62 square miles per location vs. 2 in urban areas), longer travel distances, older populations, and slower mail service.
(Secure Democracy USA, 2022)
Rural voters are more likely to vote Republican, with Republicans holding a 25-point advantage in rural areas
(Pew Research Center, 2024)
In 2020, 47% voted early or by mail (22% mail ballots), and Election Day in-person voting dropped 30% as they shifted to easier options.Rules like excuse requirements, witness/ID mandates, no drop boxes, or tight deadlines force difficult in-person trips or risk rejected ballots due to mail delays and isolation.
Estimated turnout reduction: Rural counties with no-excuse mail voting had nearly 8 percentage points higher turnout (voting-age population) than those requiring excuses in 2020.
Gaps were 5–7 points overall (strongest in the remotest counties) (Secure Democracy USA, 2022).
Broader studies show mail voting expansions boost turnout 2–9 points (Brookings Institution; MIT Election Lab), implying similar drops from restrictions.
So rural voters, who vote GOP by ~25pts really rely on Mail Ballots to participate in our constitutional republic.
Why does MAGA want to suppress their own voters?
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@GiovanneFiorel1 The Gap Cycle series by Stephen R Donaldson if you are looking for more dark and brutal.
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@kageargos @zbogus77 It is a great series. I like The Gap Cycle series even better though.
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@zbogus77 i know this is 2001 but Thomas Covenant in 8th feels crazy - i don't know that you could get people to touch it with a 10-foot-pole today
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Dominic Smiraglia retweetledi
Dominic Smiraglia retweetledi

The @BuffaloSabres and @TBLightning game saw 15 combined goals and 27 total penalties. The NHL has not seen a game reach both those totals since Flyers/Canadiens on February 21, 1994 (15 goals and 27 penalties).

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@BuffaloSabres The feed on @MSGNetworks on Spectrum cable is so bad it is almost unwatchable. So frustrating @GetSpectrum
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@Bulldogwgr @lordast111 Since the contact between stick and glove was outside the paint, couldn’t we argue the goalie interfered with Sammy’s ability to tip the puck? That said, I thought for sure it was goalie interference.
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@lordast111 Because Samuelsson’s stick prevented the goalie from fully extending and his right skate was in the crease at the same time, I believe.
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Dominic Smiraglia retweetledi

Thrilled to share our final published study @CR_AACR on the impact of EZH2 on prostate cancer lineage variant evolution.
Great teamwork with @KristineWadosky and led by David Goodrich @RoswellPark
And a beautiful commentary by Mark Rubin’s group… couldn’t get any better!
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@sebatlab I read that book in college and loved it for what it was.
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