Dominic Smiraglia

990 posts

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Dominic Smiraglia

Dominic Smiraglia

@SmiragliaLab

The SmiragliaLab studies cancer epigenetics with the idea in mind that epigenetic modifications provide an exceptional route for cancer cell ‘evolution’ .

Roswell Park Cancer Institute Katılım Nisan 2017
271 Takip Edilen237 Takipçiler
Jay Bee
Jay Bee@TheJayBee·
What else does this steak need?
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Dominic Smiraglia
Dominic Smiraglia@SmiragliaLab·
@JeremyWGR @DelReid Love that perspective. I think Vanek is the last jersey I have. My whole family has Tuch, and I will too as soon as he signs a contract with us. I love Benson, but I hate the RAT label. He is so much better than that. He plays super hard, but not anymore dirty than the next guy.
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Jeremy White 🚂
Jeremy White 🚂@JeremyWGR·
@DelReid I find it easy to turn it into “I want my kids to know who I respect”
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Del Reid 🦬
Del Reid 🦬@DelReid·
Had a whole conversation in the office last week about how as 30/40/50 somethings it feels weird wearing the jersey of someone way younger. That said, I’d rock a Benson jersey so hard
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Dominic Smiraglia
Dominic Smiraglia@SmiragliaLab·
@TheChargingBUF I couldn’t agree more. This gambling partnership, plus how the MSG broadcast promotes gambling, is gross. If people want to gamble on all sorts of aspects of the game, go for it and enjoy! Leave it out of my sporting event.
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Cynical Pain Doctor
Cynical Pain Doctor@cynicalpainmd·
@CMDeDominicis If you need a nasa physicist to determine that it’s offside, then it probably isn’t a big deal. The point of the rule is to prevent players from cherry picking, not to obsess over a millionth of an inch
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Chad DeDominicis
Chad DeDominicis@CMDeDominicis·
Omg no. This is worst case scenario for the NHL.
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x - A a r o n
x - A a r o n@23sabres·
Who’s one Sabre you think is going to bolster their value and perception after this playoff run? Someone who people would expect to play worse against playoff hockey or just isn’t currently rated the way they will be following this run
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Dominic Smiraglia
Dominic Smiraglia@SmiragliaLab·
@TageForHart Coz was really good last night. He didn’t ever look like that with us his last 1.5 seasons with us. Glad to see him bounce back, but I am happy with the trade.
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y -𝐓𝐚𝐠𝐞 𝐅𝐨𝐫 𝐇𝐚𝐫𝐭
THIS is why I get annoyed with the bandwagon fans who just started watching again this year. Cozens last couple seasons here he had quit and mailed it in. He needed a fresh start. Easy to look at one game and make a decision when you weren’t here for the background of it #Sabrehood
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Dominic Smiraglia
Dominic Smiraglia@SmiragliaLab·
@SalSports Late 70s-early 80’s. I was young and had to go to bed during playoff games against the Islanders multiple years. I listen to the game on a transistor radio under my pillow. I just remember Billy Smith hacking, slashing, and fighting. Sabres kept losing to them and I hated Smith!
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Sal Capaccio 🏈
Sal Capaccio 🏈@SalSports·
First Sabres playoff memory. Go! (mine is Bob Sauve back-to-back shutouts in games 1/2 AT the Canadiens in 1983.....1st round was only best-of-five then....Sabres swept with Game 3 win at home)
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Lindy Ruffs Burner
Lindy Ruffs Burner@Sabrestalkv2·
Benson-Carrick-Mal on the ice together is like putting 3 honey badgers on meth in a cage and shaking it up before throwing them on the ice
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Maine
Maine@TheMaineWonk·
‼️ Let’s talk about MAGA wanting to restrict mail ballots: It’s unamerican and will backfire on Republicans Rural voters are hit hardest by mail ballot restrictions because they face far fewer polling places (median ~62 square miles per location vs. 2 in urban areas), longer travel distances, older populations, and slower mail service. (Secure Democracy USA, 2022) Rural voters are more likely to vote Republican, with Republicans holding a 25-point advantage in rural areas (Pew Research Center, 2024) In 2020, 47% voted early or by mail (22% mail ballots), and Election Day in-person voting dropped 30% as they shifted to easier options.Rules like excuse requirements, witness/ID mandates, no drop boxes, or tight deadlines force difficult in-person trips or risk rejected ballots due to mail delays and isolation. Estimated turnout reduction: Rural counties with no-excuse mail voting had nearly 8 percentage points higher turnout (voting-age population) than those requiring excuses in 2020. Gaps were 5–7 points overall (strongest in the remotest counties) (Secure Democracy USA, 2022). Broader studies show mail voting expansions boost turnout 2–9 points (Brookings Institution; MIT Election Lab), implying similar drops from restrictions. So rural voters, who vote GOP by ~25pts really rely on Mail Ballots to participate in our constitutional republic. Why does MAGA want to suppress their own voters?
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Amy
Amy@20th_Centurygal·
Recommend one album everyone should listen to at least once...any genre.
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Fiorelli 📚 🎮
Fiorelli 📚 🎮@GiovanneFiorel1·
Com exceção de A Fundação e Duna, quais Livros de Space Opera vocês indicam?
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Dominic Smiraglia
Dominic Smiraglia@SmiragliaLab·
Laura Linney is absolutely spectacular in Ozark. On my second run through and it is just amazing. I hope she got some awards for it.
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Andrey 📚 - Fantasy Classic Book Club
Top 50 fantasy series according to an internet poll from 2001. I love looking at lists like this and figuring out why each series fell off and why some stayed relevant.
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Matt Kopnak
Matt Kopnak@MattKopnak·
If you were ever curious what the end of the regular season felt like in 2006. It felt like this.
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OptaSTATS
OptaSTATS@OptaSTATS·
The @BuffaloSabres and @TBLightning game saw 15 combined goals and 27 total penalties. The NHL has not seen a game reach both those totals since Flyers/Canadiens on February 21, 1994 (15 goals and 27 penalties).
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Dominic Smiraglia
Dominic Smiraglia@SmiragliaLab·
@BrianWGR @WGR550 That was great, but it is nothing compared to a playoff game. These guys only THINK they know Sabres fans!
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Brian Koziol
Brian Koziol@BrianWGR·
Dahlin on 1st intermission on @WGR550 with @pham1717 on the pregame ceremony says "that's the craziest thing I've seen at Key Bank", also said that about ten guys came up to him and said "they were ready to jump through a wall." #Sabres
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Dominic Smiraglia
Dominic Smiraglia@SmiragliaLab·
@Bulldogwgr @lordast111 Since the contact between stick and glove was outside the paint, couldn’t we argue the goalie interfered with Sammy’s ability to tip the puck? That said, I thought for sure it was goalie interference.
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Christopher Parker
Christopher Parker@Bulldogwgr·
@lordast111 Because Samuelsson’s stick prevented the goalie from fully extending and his right skate was in the crease at the same time, I believe.
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Christopher Parker
Christopher Parker@Bulldogwgr·
How in the world is that not goalie interference? I mean, thank you, but wow.
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Justine Jacobi
Justine Jacobi@JacobiJustine·
Thrilled to share our final published study @CR_AACR on the impact of EZH2 on prostate cancer lineage variant evolution. Great teamwork with @KristineWadosky and led by David Goodrich @RoswellPark And a beautiful commentary by Mark Rubin’s group… couldn’t get any better!
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Jonathan Sebat
Jonathan Sebat@sebatlab·
Years ago, I was one chapter into “the man who mistook his wife for a hat” when I realized that what I was reading was largely a work of fiction. I didn’t make it to chapter 2. There’s a long tradition of turning science into B.S. to sell books
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