SMK
298 posts

SMK
@SmkIDPA
Internal Medicine Nocturnist PA and Army National Guard Physician Assistant. Views are my own and do not reflect those of employer or DoD







🔥Just published 🔥 TAPER-V RCT Initial Vancomycin Taper for the Prevention of Recurrent Clostridioides difficile Infection In this randomized clinical trial of 256, a 4-week vancomycin pulse and taper regimen *had a probability of 74% to be superior to astandard 2-week pulse regimen in patients a first episode or first recurrence of CDI *All patients received 14d pulse of vanco (standardized at 125 mg orally 4 times a day at the time of recruitment) →taper (125 mg q12h ×7d,then 125mg q24h ×7d) vs placebo for management of CDI (first episode or recurrence). Vanco for 10d is obsolete! #IDXposts jamanetwork.com/journals/jaman…
















