St Johnston Lab

Fly lab sping cleaning

The Shot CH1 domain recognises a distinct form of F-actin during Drosophila oocyte determination Read this Research Report from Dmitry Nashchekin @DNashchekin, Iolo Squires, Andreas Prokop @Poppi62 and Daniel St Johnston @StJohnstonLab @GurdonInstitute: journals.biologists.com/dev/article/15…

Our new paper is out in @Development. journals.biologists.com/dev/article/15… @StJohnstonlab @GurdonInstitute @Poppi62

Do you want to convert an old microscope base to a light-sheet microscope that can image standard glass slide samples? Check out our new paper from @StJohnstonLab @GurdonInstitute in opg.optica.org/boe/fulltext.c… #OSA_BOEx

Checkout our new preprint where we integrate OPM (single objective light sheet) into a standard microscope base. biorxiv.org/content/10.110…

Have a paper that has been reviewed elsewhere? Journal of Cell Science is pleased to consider such manuscripts for fast-tracked decision making. Send us your manuscript together with the full set of reviews and decision letters, and we’ll use these to make a decision. Find out more at bit.ly/3ov7XTc

Funded PhD studentship available in our newest lab - so new, it is not even open yet! (Group leader Sumru Bayin arrives in March.) Join Sumru in October to work on 'Age-dependent regenerative mechanism in the brain'. Closing date 07 Feb. jobs.cam.ac.uk/job/33118/

How is one Oocyte specified from potential many? Read the latest work driven by Dima from our lab! science.org/doi/10.1126/sc…

We are looking for a new postdoc to study the composition and role of tricellular adherens junctions in epithelial morphogenesis. In collaboration with @StJohnstonLab and @LabBuckley. For more info see jobs.cam.ac.uk/job/30122/. Please share & RT. @PDN_Cambridge (@Cambridge_Uni)

All for one, and none for the rest: Symmetry breaking in oocyte determination @WilcocksonScott highlights new work by @StJohnstonLab prelights.biologists.com/?p=29663

The silent conductor of cortical polarisation: asymmetric activation of Myosin-II orchestrates A/P axis establishment in Drosophila. Highlighting new work from @StJohnstonLab, including author comments. prelights.biologists.com/highlights/the…

"This discovery paves the way for new kinds of [cancer] prevention and intervention strategies that target the mechanisms that promote...cell competition." New study of how tumour cells colonise the intestinal epithelium out now from the Simons lab: bit.ly/3uHE2UP

So great to see this published! Spearheaded by @ProfHao, @EdwardAllgeyer and Dong-Ryoung Lee, and made possible by our fantastic collaborators @ProfMartinJBoo1 @DopOxford @LynnCooley11 @BiedererLab @jacopoantonello @lenakumba @Fran_Bottanelli @phylicia_kidd @LessardMark

Checkout our new preprint where we develop a line scanning confocal system to do multi-colour super resolution imaging (DNA-PAINT) in Drosophila tissues. @EdwardAllgeyer @GurdonInstitute @Cambridge_Uni

Happy to be part of this work. Ed & George, our microscope builders, developed the custom STED scope and helped with imaging for this project! @EdwardAllgeyer @GurdonInstitute

📢I am thrilled to announce that I will join the @GurdonInstitute at the @Cambridge_Uni as a group leader in Spring 2022. The Bayin Lab will study the age-dependent regenerative mechanisms in the brain.

Excited to share a preprint with some work from my undergrad project in the St Johnston lab! 🪰 we show an important role for the MT (-) end binding protein Patronin in Drosophila oocyte selection biorxiv.org/content/10.110…

Symmetry breaking in the female germline cyst biorxiv.org/cgi/content/sh… #bioRxiv

Fundamentally important paper! Oocyte specification from the germline cyst cluster was always so mysterious to me! This work on the role if patronin in symmetry breaking is amazing! #oocyte #devbio biorxiv.org/content/10.110…