St-Pierre Lab

Huge thanks to our amazing collaborators @IBENS_ENS (Laurent Bourdieu, Vincent Villette, Jon Bradley and team), Na Ji @UCBerkeley, Brice Bathellier at l'Institut de l'Audition, and @BarnaDudok and @viajake at @bcm_neurosci. ⚔️Team science at its best!

#MayThe4th announcement: JEDI-2P was not The Last Jedi ⚔️! Introducing JEDI3sub & JEDI3hyp, the best GEVIs in this galaxy for reporting subthresholds voltage dynamics under two-photon illumination🔬#GEVIs. Check out our @naturemethods paper: nature.com/articles/s4159…

High praise to the best collaborators in the Galaxy, who deployed FORCE1s in vivo, including the teams of @WikiZong (2P miniscope), Na Ji (FACED), @IBENS_ENS (Laurent Bourdieu, Vincent Villette, Jon Bradley), and @viajake @bcm_neurosci. Contact Dr. St-Pierre for FORCE1s.

#MayThe4th be with you! Meet FORCE1s, a new positive‑going, ultrasensitive voltage indicator. Optimized for 2P imaging at slower acquisition speeds, FORCE1s is easy to use on almost any microscope. Bonus: it even powers 2P miniscope experiments!📄Preprint: biorxiv.org/content/10.648…

Grab some JEDI3 plasmid or AAV from Addgene and join the JEDI order. addgene.org/browse/article…

🚨 We’re hiring! The St-Pierre Lab at Baylor College of Medicine has exciting opportunities: 🔬 Postdoctoral position 👩‍🔬 Staff position Work on cutting-edge electrophysiology and optical tools to advance neuroscience! See: shorturl.at/uim4d #Neuroscience #Ephys #PostdocJobs

The Force Awakens at #Sfn2025 ! Join us tomorrow AM for poster LBP038: introducing FORCE1s, a positive-going GEVI engineered by the St-Pierre lab for ultrasensitive voltage detection. Stunning in vivo results from the Reimer, Bourdieu, @NaJiBerkeley, and Weijian Zhong labs.

The Return of the JEDI! St-Pierre lab poster LBP037 tomorrow AM @ #Sfn2025: unveiling JEDI3 — next-gen Genetically Encoded Voltage Indicators (GEVIs) for enhanced detection of subthresholds under 2P. Great collaboration with the Bourdieu,@NaJiBerkeley, @BarnaDudok & Reimer labs

Excited to share our latest paper, where the @EmilianiLab used our #JEDI-2P-Kv indicators for high-SNR scanless 2P voltage imaging of multiple cells in vivo, and combined voltage imaging and optogenetics. Don't miss the 17 supplementary figures 😲! doi.org/10.1038/s41467…

🚀 Exciting Opportunity Alert! 🚀 Join our dynamic team at St-Pierre Lab at BCM as a Postdoctoral Researcher! Work on cutting-edge projects and contribute to groundbreaking discoveries. Apply now and be part of our innovative research community! #Postdoc #Opportunity

Putting the final touches on my upcoming talk for the @CNPviralvectors satellite meeting at the @CAN_ACN conference, all while enjoying the stunning views of beautiful @CityofVancouver, my beloved home country of Canada!

@HelenXiaoyuLu couldn't come to Houston to accept her @RiceSSPB thesis award, so I brought it to her in Seattle!

Congrats to @HelenXiaoyuLu, an outstanding recent lab alum who won a @RiceSSPB thesis award 🏆! Xiaoyu is now a Scientist at @AllenInstitute and so couldn't attend. I attempted to accept on her behalf, disguised with her face on cardboard🎭, but my cover was blown quickly!

🥂Celebrating 5 incredible years with Shujuan Lai in our lab @bcm_neurosci. She's been pivotal in developing photostable fluorescent proteins and our SPOTlight single-cell screening platform. She gave an inspiring speech🎤emphasizing the power of grit in achieving dreams.

Dr. Francois St-Pierre led an illuminating session on "Advanced Concepts in Voltage Imaging" at the Optogenetics and Wavefront Shaping program in Paris. Unlocking new insights into brain functioning! #Neuroscience #Optogenetics #ParisConference 🌟

Saying goodbye to Xiaoyu Lu with a memorable lunch!🔬🤠Your success in the lab has been nothing short of amazing. Saying goodbye is tough, but we're excited for your next steps. Can't wait to see your future achievements! Best wishes, Xiaoyu! #FarewellXiaoyu

🎉 Congratulations to Shujuan Lai on her well-deserved promotion to Research Associate in the St-Pierre lab! 🙌🔬 Your dedication and hard work have truly elevated our research efforts. Thank you for being an invaluable part of our team! 🌟 #ResearchExcellence #TeamWork 🎊👏

Big thanks to Prof. Dieter Jaeger for inviting me to the Emory U. Bio seminar series last week, and to Malia Escobar for ensuring a seamless visit. Loved engaging with the brilliant grad students and faculty. Astonished by Emory's massive neuroscience network – over 120 labs!

Enjoy leadership advice and words of hope from a @Neurophotonics Editorial from Editor-in-Chief @AnnaDevor and Shadi Dayeh!

@weinberz The perspective that photostability measurements are made up suggests this post is satirical. I certainly hope so!

@weinberz Bioengineers are developing fluorescent proteins (FPs) for many applications: superresolution microscopy, photo labeling, FRET biosensors, extended timescale imaging, etc. It's great if your lab is well served by existing FPs, but we need to consider the broader community.