StainsFile

Welcome to StainsFile by @STEMCELLTech! Here, you can enjoy easy and open access to all the protocols and supporting resources you need to help you fix, prepare, and stain specimens: stainsfile.com 👩🏽‍🔬💻🧫🔬 #cellstaining #histology #microscopy #microscopymonday

Introducing FidlTrack from @Cambridge_Uni! This new methodology benchmarks and improves Single Particle Tracking fidelity, making understanding dynamic behaviors of macromolecules within live cells even more accessible. Abstract: go.nature.com/4eozahO

Three new neural network-based tools enable fast, accurate alignment and annotation of images even in very wiggly subjects. The tools from the Flavell lab at @MIT_Picower might offer a way to automate cell tracking in other imaging datasets: bit.ly/3Qe6wGb

Your images could teach the world. 🔬 If you’re working with immunohistochemistry or immunofluorescence, consider sharing your best visuals with StainsFile, a growing hub for histology knowledge and inspiration. Upload here: bit.ly/48GRXBT

Researchers from Jilin University have synthesized a new dye with significant fluorescence enhancement. Their nonamethine dyes aid in deep tissue imaging with high contrast under complicated biological conditions. View the abstract: bit.ly/3Q3UpeX

Advance your expertise in perinatal #pathology without leaving your desk. 💻🔬 Join the 2026 Perinatal Pathology Virtual Course from August 20–22 for three days of expert-led sessions covering placental pathology, perinatal autopsy, and emerging topics shaping the field: bit.ly/487pPaq

🧪 Ever wondered how scientists visualize lipids under the microscope? Meet lysochromes: fat-soluble dyes that dissolve directly into lipids to reveal their presence and distribution in cells. 🔬 Dive into the theory behind lysochromes: bit.ly/4cM5oCn

Cancer research emphasizes early detection, but quantitative methods for tissue analysis are limited. Dr. Anita Grigoriadis (@KingsCollegeLon) developed a convolutional neural network-based classification model for normal breast tissue at different scales: go.nature.com/4bejFGc

In this piece from The Pathologist, Dr. Dariusz Borys explores how bringing together radiology and pathology could lead to more accurate cancer diagnoses and better patient care. Explore how collaboration could be the next step in modern diagnostics: bit.ly/4d6kpzA

New work from Fudan University makes multimodal spatial profiling more accessible! SpatialEx+ is a computational framework leveraging histology as a universal anchor to integrate spatial molecular data across tissue sections. @naturemethods: go.nature.com/4btm40P

New tools are bringing tumor samples into technicolor. "We are seeing absolutely entrancing images that are expanding our understanding of what happens when we harness immunity against a tumor," says Dr. Catherine Wu at @DanaFarber. 🌈 bit.ly/4qe1zdI

🔬 Need a reliable way to highlight amyloid deposits in tissue sections? Check out the Bancroft’s Methyl Green for Amyloid staining protocol and learn a classic method to get a clear contrast in nuclei and surrounding tissue. 📄: bit.ly/4b5iMzy

Altair light-sheet fluorescence microscopy is a high-resolution, open-source, sample-scanning light-sheet microscope specifically designed for subcellular imaging. Made by the Dean lab at @UTSWMedCenter, it's a game changer for live-cell imaging. @eLife: bit.ly/4spEJ3h

🎧 New Podcast Alert! Dive into Case Encounters, where real-world medical mysteries are brought to life through story-driven episodes inspired by actual pathology cases. Discover what happens when science meets mystery! 🔍 apple.co/3NpbqPz #SciencePodcast

Tiny but mighty! Check out the incredible vasculature network that can be found in an adult mouse's spinal cord. 🐁 bit.ly/3PXtdOV Credit: Dr. Andrea Tedeschi

🚨 Deadline Alert: You have TWO DAYS left to apply for a 2026 HCS Capstone Grant! HCS is awarding $2,000 grants to support undergraduate research using immunohistochemistry & histochemical techniques. 📅 Deadline: April 15, 2026 To learn more and apply: hcs.memberclicks.net/capstone-grants #UndergradResearch #Histochemistry #ResearchFunding

What's a great way to embed small, fragmented tissues together without loss? Gelatin encapsulation followed by paraffin wax processing can help you prep and section sample blocks with ease. Check out the protocol 👉 bit.ly/4bxVLpp

In a new study, researchers showcase the Histo-LOOP embedding tool, a novel tool designed to standardize, simplify, and improve #histological processing. Histo-LOOP allows for a complete overview in cross-sectional and longitudinal views. Abstract: bit.ly/4brFZgK

Happy Friday! We hope the beauty of this butterfly wing lifts your spirits and carries you gracefully through the weekend. 🦋 bit.ly/47PL0NX Credit: Evan Darling

#ThrowbackThursday in JHC: "MATLAB-based Methods Allow Precise, High-Throughput Quantification of Nuclear Morphology and Texture in Tachycardiomyopathy." Click to read for FREE: bit.ly/3ELqL8R #MATLAB #tachycardiomyopathy #digitalimageanalysis

Is the "relocation rule" real? 🧳 If you’re weighing a postdoc move, considering a faculty position, or thinking strategically about long-term independence, the latest episode of Lab Coats & Life™ Podcast offers a grounded and practical perspective. #GradLife