Steve Coast

A 16-hour fasting regimen may boost cancer immunotherapy. Transient nutrient stress reshapes tumor metabolism, increasing isoleucine in the TME and enhancing CD8+ T cell function. In mice & patients, short-term fasting improved immune response—offering a feasible way to strengthen treatment. #Fasting, #immunotherapy, #cancer, cell.com/cell-metabolis…

Yesterday I drove my @tesla 900 miles on FSD from Miami to Nashville and I realized it’s genuinely the better option. I fly that route 2 to 3 times a month. Flights are never under $400. Most times $600. Sometimes $800. Add Uber to and from both airports, or parking garage fees. Then factor in the delays, the cancellations, the security theater, the chaos, the guy next to you who hasn’t met deodorant yet. On the other hand: I pack healthy snacks, press one button, and the car just goes. I took calls. Replied to emails. FaceTimed my family. Ate without pulling over. Did everything I normally do on a travel day, except none of the stuff that makes travel days miserable. My biggest concern going in was range and charging. Here’s what actually happened: My bladder needed one extra stop the car didn’t even suggest. Most charging stops were under five minutes. Total cost for the whole trip was less than just the uber to the airport. And this was the base model Y. Now I’m thinking I should get something comfier and just make this the default.