Steyn_Lab

Enjoying several expert talks by key metabolism researchers, including the talented @SezSaysScience as part of the @UQMedicine supported Mini-symposium on #metabolism.

Congratulations to the amazing researchers awarded @FightMND funding to support much needed research into improving our understanding of #MND. Thank you to every donor that made this possible.

Enjoying quiet time in the lab as @melkg97 @StephanieHowe98 and @AmberGreen67157 take on the challenge of not speaking for 48hrs to support those who have lost their voices to #ALS #MND. Click below to support a worthy cause👇@MNDFoundation @UQMedicine secure.mndandme.com.au/my-fundraising…?

We will be extending abstract submission until CoB Tuesday 26th September for those of you running a bit tight to the deadline! somersetevents.eventsair.com/mnd/call-for-a…

Very grateful for an opportunity to learn from an amazing lineup of delegates across the Asia-Pacific regions at the 2023 @pactals meeting. Looking forward to building better research connections

5/5 - #ghrelin acts on the #hypothalamus 🧠to regulate #hunger 🍔 #metabolism 🔥; can we strengthen this to benefit #PALS. Thank you to @MND_RIA @UQMedicine, and @FightMND and @NIHfor supporting @NgoShyuan @ZigmanLab. A BIG thank you to the #PALS for their time and contributions

In, this #OpenAccess manuscript by the talented EMCR @StephanieHowe98 et al., we explored associations between #Ghrelinand #LEAP2 (endocrine factors and regulators of #appetite) in ALS; findings were somewhat unexpected. A thread to help explain (1 of 5) doi.org/10.1111/ene.16…

4/5 – #PALS with higher #ghrelin were more likely to have lower #BMI & #FatMass, suggesting they were at greater risk of #malnutrition. They also had greater risk of earlier death; are benefits of ghrelin lost, and can we target this to improve outcomes? More research 🔬needed.

3/5 – When comparing findings with functional decline, lower #ghrelin and greater #LEAP2ghrelin was associated with lower physical capacity; #ghrelin does more than regulate appetite. It can be neuroprotective 🧠 and support muscle 💪 function. Are these benefits lost in #ALS?

2/5 - Seeking to improve understanding of why some #PALS lose appetite, we show that postprandial hunger hormone #ghrelin is lower in ALS, and a big increase in #LEAP2ghrelin, suggesting #LEAP2 might block #ghrelin actions. @ZigmanLab was instrumental in making sense of this.

Abstracts are open for the Aus/NZ #MND Research Symposium 2023 in beautiful Wollongong 17-18 November. Talks will be selected from abstracts, lots of options available for #EMCRs @mndaustralia @FightMND @MNDNSW @UOW @wollongong_nsw Pls RT mndaustralia.org.au/research/2023-…

A quick snapshot of our lab at @GRIDD_GU @GU_Sciences! 😎 Dont forget we have 2 positions to join our group! *Postdoc lnkd.in/e_U35C88 *RA lnkd.in/eDr3N_Hy# #zebrafish, #DiseaseModels, #Neurodegeneration, #MND, #drugdiscovery, #genetics, #schizophrenia, #microscopy

Hi Network, we are recruiting!!!! Research Fellow and Research Assistant. If you want to be part of a dynamic team who plays with genetics, develops cell/zebrafish models of human diseases and conducts drug discovery campaigns! You should have a look 👇 1/3 Please share 🙏

@FightMND @Fred_Steyn @HoldomCory Excited to have the very talented #EMCR @HoldomCory join the discussion as he provides insights into his recent manuscript; if interested, you can find a copy here - doi.org/10.1007/s00415…

Our Scientific Seminar Series is back with a new time on Tues, Feb 28 at 12pm AEDT! Our first talk is @Fred_Steyn & @HoldomCory from @Steyn_Lab with 'Use and validation of digital technologies, including actigraphy, for care and research in MND.' For more fal.cn/3vUfr

Collaborative project between @UQ_News and @UMCUtrecht showing that wear location will impact #actigraphy outcomes in #ALS #MND Led by #PhD student @HoldomCory with insights from @rpavaneijk. Thank you for support from @HondaFoundation @WesleyResearch @MNDFoundation @FightMND

I'm excited to share our paper following from @rpavaneijk's work on the use of passive actigraphy for monitoring #ALS #MND function outside the clinic. There is clearly a lot of opportunity to expand the potential of this technology. @Steyn_Lab @Ngo_Lab: doi.org/10.1007/s00415…

Thank you for sharing the blog - great summary of the talk by @NgoShyuan

Does hypothalamus size matter in #ALS? Patients with low hypothalamic volume with low BMI tend to lose fat mass and have increased risk for earlier death. Thank you to the #PALS and their friends and family who contributed to this work. doi.org/10.1111/ene.15…🧠@EANeurology (1/4)