Stroke Prevention

In this topical review, @VYogendrakumar and colleagues critically appraise the literature on the use of imaging to guide eligibility for reperfusion therapy in acute ischemic #stroke. @NguyenThanhMD @SCouttsMD @AbdalkaderMD ahajrnls.org/3ONysAm

#MondayTip Can we prevent stroke without increasing bleeding? Factor XIa inhibition #asundexian : 🔹⬇️recurrent stroke (HR 0.74) 🔸with no ⬆️major bleeding in OCEANIC-STROKE. A potential shift in secondary prevention. 🧠⚖️ 🔗 nejm.org/doi/full/10.10…

Preventive cardiology is at an inflection point. An important read by @DrMichaelShapir 📚 Despite decades of progress, rising rates of obesity, diabetes, and cardiometabolic risk are threatening to stall, and even reverse, gains in cardiovascular outcomes, underscoring the urgent need for a paradigm shift toward prevention. This timely article highlights a critical moment for our field: one that calls for stronger integration of risk assessment, earlier intervention, multidisciplinary care, and scalable implementation strategies. As the evidence base grows, so too must our commitment to translating prevention into everyday clinical practice. At @ASPCardio, we see this as an opportunity—to redefine care, strengthen education, and lead the next era of cardiovascular prevention. sciencedirect.com/science/articl… #PreventiveCardiology #CardioPrevention #HealthEquity #Cardiology #ASPC

In the phase 3 OCEANIC-STROKE trial involving patients with noncardioembolic ischemic stroke or high-risk TIA, asundexian added to antiplatelet therapy led to a lower risk of ischemic stroke without increasing major bleeding. Full trial results: nejm.org/doi/full/10.10… Editorial: Asundexian for Noncardioembolic Ischemic Stroke nejm.org/doi/full/10.10…

“Perfusion Scotoma” (when CTP don't see the core) is present in 25% of acute ischemic #stroke and associated with more distal occlusions and longer onset-to-CT-time. Terrific paper from @Libero131087 published in @TheAJNR! @johanna_ospel @alessandro5161 ajnr.org/content/early/…

Highly-recommended review on #dyslipidemia management for #stroke prevention. Learned a lot from this one! @IntJStroke @WorldStrokeOrg @WorldStrokeEd Kudos to the Authors! #supplementary-materials" target="_blank" rel="nofollow noopener">journals.sagepub.com/doi/10.1177/17…

Among patients with atherosclerotic cardiovascular disease, targeting an LDL cholesterol level below 55 mg per deciliter led to a lower 3-year risk of cardiovascular events than targeting a level below 70 mg per deciliter. Full Ez-PAVE trial results and Research Summary: nejm.org/doi/full/10.10…

Reversible cerebral vasoconstriction syndrome: A narrative review CCR Journal Watch criticalcarereviews.com/latest-evidenc…

Published today, 2026 Dietary Guidance to Improve Cardiovascular Health: A Scientific Statement from the American Heart Association. This statement: ➡️ Reinforces the importance of focusing on heart-healthy dietary patterns, rather than on single foods or nutrients. ➡️ Highlights the importance of adopting heart-healthy eating habits early in life and maintaining them across the life course. ➡️ Organizes the guidance into nine features to facilitate adoption of a dietary pattern that support cardiovascular health. ➡️ Recognizes the additional benefits that come with adoption of a heart-healthy dietary pattern beyond CVD. 📷 Features of a dietary pattern to promote cardiovascular health.

Original Article: Left Atrial Appendage Closure or Anticoagulation for Atrial Fibrillation (CHAMPION-AF) nejm.org/doi/full/10.10… Editorial: Left Atrial Appendage Closure — Should Recommendations Be Expanded? nejm.org/doi/full/10.10… #ACC26 | @ACCinTouch

Original Article: Intensive LDL Cholesterol Targeting in Atherosclerotic Cardiovascular Disease (Ez-PAVE trial) nejm.org/doi/full/10.10… Editorial: Paving the Road toward Targeted Lipid Lowering nejm.org/doi/full/10.10… #ACC26 | @ACCinTouch

Share this #CardioSmart infographic with your patients to explain high Lp(a), why knowing levels is important, and its impact on heart health. Learn more: bit.ly/4rMSOal #KnowLpa #LpaAwarenessDay

The 2026 Guideline on the Management of Dyslipidemia was recently published. Here are the top 10 things for health care professionals to know.

ICYMI: Check out #Stroke #EditorPick, "Timing of Initiation and Efficacy of Dual Antiplatelet Therapy in Minor Stroke or High-Risk TIA." @KimBJstroke ahajournals.org/doi/full/10.11…

A Standardized Anatomical Classification of Intracranial Hemorrhage. Hope is gonna simplify communication. @Ash_Shoamanesh @PrCCordonnier @sheth_kevin @JoshGoldsteinMD @vagal01 @SalmanRust94258 @DavidSeiffge @demchuk_andrew @HUNIMED @DCNSNeuro #stroke karger.com/ced/article/do…

Just added TRACE-5 to neurobedside. Tenecteplase vs standard treatment for basilar artery occlusion within 24h. 38% vs 29% achieved excellent functional outcome (p=0.014), with no increase in hemorrhage or death. Big deal for centers without 24/7 thrombectomy access. neurobedside.com

The 2026 ACC/AHA Multisociety #Dyslipidemia Guideline-at-a-Glance offers a visual summary of key updates in CV risk assessment, lipid treatment goals, & #ASCVD risk reduction. A quick reference for clinicians: jacc.org/doi/10.1016/j.… #JACC #ClinicalGuidelines #cvLipids

Check out this new editorial from Stroke: Vascular and Interventional Neurology—a quick, insightful read you won't want to miss. ahajrnls.org/3PdQvja

Among patients with atrial fibrillation at high risk for stroke and bleeding, left atrial appendage closure was not noninferior to medical therapy in reducing the risk of stroke, embolism, major bleeding, or death at 3 years. Full CLOSURE-AF trial results: nejm.org/doi/full/10.10… Editorial: Left Atrial Appendage Closure — Another Overused Method in Cardiology? nejm.org/doi/full/10.10…