Joshua Hislop

I’m very excited to share that my manuscript in Nature is out today! I am honored that our model is a part of the “method of the year” crowd, and with some exciting things to show in the full publication! (Including a new name: heX-Embryoids!) 1/n nature.com/articles/s4158…

- Barcode-traced hypoblast fate in human embryo models; - The first blood comes from the hypoblast that contributes to hemoglobin+ phagocyte-like cells; - CDX2 marks hypoblast blood that sustains oxygen supply in embryos before heart formation; - Erythro-core regulatory network endows erythropoiesis to human hypoblasts and phagocytes. The study was led by @chao_yiming now on job market.

Had a great time discussing our new studies on how embryo builds itself & how it can be used for #regenerative #medicine with my friend and colleague Susana Chuva de Sousa Lopes visiting #Pittsburgh @MageeWomens #embryomodel #Development @SynCellJoshua

Spatial transcriptomic characterization of a Carnegie stage 7 human embryo pubmed.ncbi.nlm.nih.gov/39794460/

Initiation and maintenance of the pluripotent epiblast in pre-implantation human development is independent of NODAL signaling: Developmental Cell cell.com/developmental-…

New work by Mia Yang's lab reports evidence of prevalent aneuploidies in human trophoblast stem cells and suggests that chromosomal instability may be a normal feature of placental development. biorxiv.org/content/10.110…

📢 Save the date! I am excited to announce the International Dutch Embryo Model Meeting 2025 in Nijmegen (NL) on Thursday 27 March and Friday 28 March! Registration is open now, or more information: ru.nl/en/about-us/ev…. Direct link to registration webforms.ru.nl/0d5d3b2f-3d7f-….

Had great visit and fantastic time presenting our lab work on human multicellular models form #stemcells #synbio @JohnsHopkins #biomedical engineering department @JHUBME thanks @cahanLab for the invite !

We think that all memory is stored in the brain. But our study published today in @NatureComms shows that all cells—even kidney cells—can count, detect patterns, store memories, and do so similarly to brain cells. My first (co)corresponding author paper!🧵nature.com/articles/s4146…

Get ready for two exciting talks this Thursday! ✨ ⁃Modeling human embryogenesis and yolk sac blood emergence with @MoEbrahimkhani ⁃The evolutionary basis of cell competition in development with @nika_shakiba 🗓️ Nov 7, 12:30 EST / 18:30 CET / 17:30 UTC 🕥

Need a break from current events and doom-scrolling? Join us tomorrow for some exciting science! Register here for #VGZT seminars if you haven't already: vgzt.weebly.com

The 4th session of the #PETconf24 is dedicated to ethics and will look at the ethical challenges around #embryo donation, the status and regulation of #stemcells based embryo models and changing public attitudes. Full details at progress.org.uk/event/embryo-s… #ethics #bioethics

This stunning image won our annual image competition and has made its way to our website. It shows twin chicken embryos with a joint body stained for N-cadherin (magenta), actin (yellow) and nuclei (cyan) and was captured by UCL student Brendan Chiong who visited the @xiongfz lab for a summer placement funded by @CRUKCamCentre.

Ready to take your next step in research independence? We are accepting applications for the Loke CTR Next Generation Fellowship in reproductive and placental biology. Find out more about our 3-year fellowship at trophoblast.cam.ac.uk/next-generatio… Please spread the word in your networks!

Curious embryo fact 1/25 The embryo is the only machine that needs to function while it is being built. This is made possible by extraembryonic tissues. They allow the embryo to breathe without lungs and to eat in the absence of digestive organs. #embryo #reproduction

First talk #ITMAT2024! by @MoEbrahimkhani #TranslationalScience

📢 Check out our @teamstembryo @NatureCellBio News & Views with postdoc @alex_schauer_ on the latest feat in human stem-cell-based embryo models by @Nobu_Hamazaki, @JShendure & colleagues. Full text: rdcu.be/dWw3c nature.com/articles/s4155… #gastruloids

Dear friends who write NSF GRFP rec letters, this year rec letters are due BEFORE the applications, so about 10 days earlier than normal on Oct. 11. Please don't let NSF's deadline change on rec letters screw over the applicants in your lives.

It was truly exciting to contribute to this work with @NRivron @bulutkarslioglu and entire team... Congratulations to everyone involved... 🙂

'Scientists have just turned giant panda skin cells into stem cells' sciencenews.org/article/giant-… Paper: science.org/doi/10.1126/sc…