SynStrategy

The newest update to @SynStrategy is live, bringing a top requested feature: a quiz function! Save reactions to custom datasets and test your knowledge across 3 quiz or flashcard formats. Check it out! iOS: apps.apple.com/de/app/synstra… Android: play.google.com/store/apps/det… #ChemTwitter

Link to the #TotalSynthesis of (+)-Neaumycin B: onlinelibrary.wiley.com/doi/abs/10.100… Explore more reactions and their synthetic applications and download the app! iOS: apps.apple.com/de/app/synstra… Android: play.google.com/store/apps/det…

The Marshall propargylation is a palladium-catalyzed stereoselective addition of a propargyl group to an aldehyde, affording homopropargylic alcohols. This method was utilized in the #TotalSynthesis of (+)-Neaumycin B by the Wang, Zhang, and Chen groups. Links in thread!

Link to the #TotalSynthesis of (+)-Vulgarisin B: onlinelibrary.wiley.com/doi/abs/10.100… Explore more reactions and their synthetic applications and download the app! iOS: apps.apple.com/de/app/synstra… Android: play.google.com/store/apps/det…

The [2,3]-Wittig rearrangement can occur when allylic ethers are treated with a strong base, transforming them into homoallylic alcohols. An application was reported by the Ding Group in the #TotalSynthesis of (+)-Vulgarisin B. Links in thread!

Link to the #TotalSynthesis of (-)-Laulimalide: pubs.acs.org/doi/10.1021/ja… Explore more reactions and their synthetic applications! iOS: apps.apple.com/de/app/synstra… Android: play.google.com/store/apps/det…

The Ohira-Bestmann reagent transforms aldehydes into terminal alkynes under mild conditions. A notable application was reported by the Wender group ( @StanfordUChem ) in their #TotalSynthesis of (-)-Laulimalide. Links in thread!

Link to the Total Synthesis of (-)-Azadirachtin: onlinelibrary.wiley.com/doi/abs/10.100… Explore more reactions and their synthetic application! iOS: apps.apple.com/de/app/synstra… Android: play.google.com/store/apps/det…

The Saucy-Marbet rearrangement: a [3,3]-sigmatropic shift turning propargyl vinyl ethers into allenic carbonyls. Notable Application: The total synthesis of (–)-Azadirachtin by the Ley group, where it was used to construct a C-C bond between two fragments. Link in 💬 below!

Our postdoc @Willi_Amberg built @SynStrategy a learning tool that categorizes 500+ reactions by functional group with 400+ total synthesis examples. If you’re into #OrgChem, check it out (it’s free)! iOS: apps.apple.com/de/app/synstra… Android: play.google.com/store/apps/det… #ChemTwitter