Thomas V. Sydenham
447 posts

Thomas V. Sydenham
@TSydenhamDK
Senior registrar, associate proff., Clin. Micro., Odense, Denmark. Diagnostics, antimicrobial stewardship, infection control.
Odense, Denmark Katılım Aralık 2014
240 Takip Edilen147 Takipçiler

@prasad_prithiv @IM_Crit_ You can perform MALDI-TOF MS directly from positive blood culture bottles prior to growth on culture plates with a high rate of success (80-90%).
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The first three to come and ask in person get my abstract reviewer coffee vouchers. At poster P3276. #ECCMID2024 / #ESCMIDGlobal and we can discuss prospective rutine WGS of health care associated bacteraemia!

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Thomas V. Sydenham retweetledi

Sanne Løkkegaard Larsen is presenting our new approach for identification of bacteria in patient samples using Nanopore Technology at a poster flash session 🤗. #ECCMID2024 #ESCMIDGlobal #clinicalmicrobiology #16Ssequencing #Oxfordnanoporetechnology #Nanopore

Barcelona, Spain 🇪🇸 English

@BradSpellberg @ABsteward @microregistrar "Optimising treatment" or "targeting treatment" seems to work
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@ABsteward @microregistrar Yeah this whole "step-down" thing has gotta stop.
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Benefits of oral "step-down" therapy in IE
Would call it oral transitional or oral switch though
OPAT vs Oral switch in IE
#ESCMIDGlobal2024 #IDXposts
A slide shared by @microregistrar

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@DrNeilStone 11 years ago two esteemed Danish Clinical Microbiologists and Infectious disease experts wrote this obituary for the term. (In Danish) sundhedsstyrelsen.dk/da/udgivelser/…
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#IDTwitter #IDXposts CASE UPDATE: Patient died next day in septic shock and MODS. His therapy on the day of death was cefepime, levofloxacin and linezolid. Post-portem blood culture result came up 👇 He didn't stood a chance...

Boris Jegorović, MD, PhD, DTM&H@BJegorovic
#IDTwitter #IDXposts A 80-years old gentleman was admitted for AKI requiring hemodialysis. On admission ceftriaxone was started because of elevated WBC (24) and lung crackles on the left. There was no fever and CRP was normal. On 2nd day of hospitalization his CRP rose to 150 👇
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@ABsteward @padstamundo This, by colleagues of mine, sheds more light on the issue. Species dependant associated risk. academic.oup.com/cid/article-ab…
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Although much attention has been afforded to S. bovis,there are many other isolates associated w higher risk for colorectal cancer-associated BSI
🆕️⚡️BSI associated with a 16-fold annualized increased⬆️ risk for diagnosis of colorectal CA @padstamundo
amjmed.com/article/S0002-…
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@IDdoc_DK @BJegorovic And + gentamicin for synergy. Also we prefer peni/ampi over meropenem, due to narrow spectrum, case reports of treatment failure and retrospective data associating Mero with higher mortality. sciencedirect.com/science/articl…
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#IDtwitter Listeria meningitis in patient with sulpha-allergy and in case when ampicillin is not available. How would you treat?
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@LpeixeLuisa Sandoz recalled all Dicillin and have now apparently made the decision to cease production withdraw Dicillin from the market permenantly. As far as I can gather the product from Sandoz was only marketed in Denmark and Iceland. (Paywalled and in Danish). medwatch.dk/samfund/articl…
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For the European colleagues: is DIciclin available in your country? Maybe you will have the same bug: Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023 eurosurveillance.org/content/10.280…
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Yes! And if you're at #ECCMID2023 you can hear Charlotte present the case tomorrow at 0830 in Hall P. (Might be prudent to get there early... Hall P does not have many seats).
Neil Stone@DrNeilStone
What a story Gram positive active antibiotic tablets contaminated with gram negative bacteria.. #ECCMID23 #ECCMID2023
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At #ECCMID2023 ? Don't miss this poster describing the bioinformatics pipeline for routine isolate WGS @microbiologikat has implemented at our department.
Kat S.@microbiologikat
Just set up my poster on our user-friendly bioinformatics pipeline for routine bacterial NGS analysis - come check it out during today’s poster session at #ECCMID2023 !
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At #ECCMID2023? Don't miss the session on Infectious disease diagnostics in light of the new EU regulation (IVDR). Organised in colab by The Danish and Swedish Societies for Clin micro and @ESGEM_ESCMID. April 18th at 11 in Hall G

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At #ECCMID2023? Don't miss the session on Point-of-Care testing organised by The Danish Society for Clinical Microbiology on April 17th.

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Siden 1996 har DANMAP-rapporterne gjort det muligt at følge antibiotika-forbrug og målepunkter i DK. Datagrundlag fra de Kliniske Mikrobiologiske Afdelinger og SSI gør det muligt at følge påvisning af mikroorganismer og antimikrobiel resistens. danmap.org
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Et historisk perspektiv kan fås ved at læse artiklen "Antibiotic stewardship" side 98 i DSKMs 50 års jubilæumsbog. dskm.dk/publikationer/…

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Til scandinavisk webinar om Antimicrobial Stewardship, hvor Klinisk Mikrobiologisk Afdeling @HerlevGentofte beskriver, hvordan klinisk mikrobiologi i årtier har arbejdet aktivt med at understøtte rationel brug af #antibiotika i Danmark. @regionerne @SSTSundhed @SSI_dk

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@SundermannAJ Yes. And it gets worse. The unique plasmids we identified in the capsule isolates, have been found in several clinical isolates of other Enterobacterales species such as E. coli and Klebsiella spp. ssi.dk/sygdomme-bered… (in Danish)

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Klinisk Mikrobiologi @HerlevGentofte deler viden om rationel antibiotika behandling og diagnostik af infektioner. Relevant fagligt program til årsmøde for Dansk Selskab for Klinisk Mikrobiologi. #antibiotika #infektion

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