Taconic Biosciences

New Alzheimer’s research in #ScienceAdvances highlights the combined use of human iPSC neural cultures and in vivo models to study disease mutations. Taconic Biosciences developed the custom Rin3 KO mouse model used in this publication. Read now: hubs.li/Q049475X0

Join Taconic Biosciences in San Diego during #AACR2026 to celebrate the acquisition of TransCure bioServices and the launch of a new integrated translational research platform. 📅 Tuesday, April 21, 2026 📍 Sparks Gallery 🕡 6:30–9:30 pm PT RSVP now: hubs.li/Q049L5yC0

Last chance to register! DIO models are evolving in cardiometabolic research. Join us for a webinar to learn how DIO models inform HFpEF & chronic kidney disease, plus two-hit strategies. Register now to advance your cardiometabolic research: bit.ly/4sc3Ber

Taconic & TransCure share a long-standing commitment to responsible, high‑quality in vivo research. Across AAALAC‑accredited sites in the US and EU, we focus on better models, streamlined workflows, and smart use of non‑animal methods when appropriate. 🔗 hubs.li/Q048F85k0

Introducing NeoThy™ Human Immune Engraftment Platform—a new approach to humanized immune system modeling. Combining neonatal thymic tissue with CD34⁺ cells, it enables HLA-restricted T cell development for more physiologic responses in vivo. Learn more: hubs.li/Q048tc3t0

Looking to improve translational relevance in oncology studies? Join Taconic + TransCure bioServices for a webinar exploring how HIS mouse models enhance preclinical research and support smarter, modular study design. 📅 March 31, 2026 Register now: hubs.li/Q047ygGJ0

Using B6 mice? Substrain matters. Genetic and phenotypic differences across B6 substrains can influence experimental outcomes and downstream analyses. Learn how to select the right B6 model for your research: hubs.ly/Q046wMSx0

The combined Taconic–TransCure supports studies in immuno-oncology, inflammatory & infectious diseases, and advanced therapies (bispecifics, ADCs, cell therapies). Aligning the right model with study design improves clarity in key decisions. Explore now: hubs.li/Q047jzBz0

Join us at #AACR2026 in San Diego, April 17–22! Visit Booth #3427 or our scientific posters to see how our preclinical models support translational oncology. We look forward to connecting with fellow researchers. Connect with us at the event: hubs.li/Q0479fpd0

Taconic’s Diet-Induced Obese (DIO) Rat supports obesity and metabolic disease studies where rat physiology and larger size matter. On a high-fat diet, it develops key features like increased weight, glucose intolerance, and insulin resistance. Learn more: hubs.li/Q046r7cY0

Understanding immune cell function requires the right model. A recent @ImmunityCP study used Rag2/Il2rg double-knockout mice to separate the roles of lymphocytes and innate lymphoid cells in disease mechanisms. Read the article: hubs.li/Q046wDk10 #TranslationalResearch

Clinical insights are feeding back into preclinical models to uncover mechanisms behind obesity therapies. A recent Indiana University study used the DIO B6 mouse to test leptin + tirzepatide, showing weight loss and metabolic improvements. Read more: hubs.li/Q046JB6r0

Join us for a #webinar on March 31, sharing insights from a decade of oncology studies. Learn how a modular study design can align humanized mouse models with mechanism of action, tumor biology, and translational goals. Register: hubs.li/Q045LVyW0 linkedin.com/events/lessons…

We're looking forward to partnering with Gubra at AD/PD2026 to present new research on 3D whole-brain imaging of β-amyloid plaques in the APP-PS1 (ARTE10) Alzheimer’s disease mouse model. See how we're advancing Alzheimer's disease research: hubs.li/Q0468G580

Happy International Women’s Day! Today, we celebrate the achievements and impact of women around the world. At Taconic, we value the many contributions women make across science, innovation, and our global community. Hear from Lesley Tomlin on what this day means to her.

How do age and sex influence amyloid pathology in Alzheimer’s disease? Taconic and Gubra used 3D light sheet fluorescence microscopy to map whole-brain Aβ plaque deposition across age in the ARTE10 model. See how advanced imaging supports AD research: hubs.li/Q045s6lH0

With TransCure bioServices now part of Taconic, we’ve expanded support for humanized mouse studies—from model generation and cohort development to in vivo execution and readout. An integrated path from study design to results, with fewer handoffs. 🔗: bit.ly/4snuYTt

We’re partnering with Transpharmation at AD/PD 2026 to present research on the APP/PS1 (ARTE10) model and its translational potential for Alzheimer’s disease and mood-related comorbidities. See how it’s advancing AD research & therapy development: bit.ly/4bjmjeR

Today, we honor National Science Day and the discoveries improving lives. As shared by Taconic's Director of Research & Development, Janell Richardson, PhD, innovation begins with curiosity. Let’s keep asking bold questions and empowering the next generation of innovators.

Off-target mutations can compromise your model and your research. Taconic’s #CRISPR Off-Target Analysis uses next-generation sequencing to detect off-target effects, so you can trust your model’s genetic integrity. Learn more: hubs.li/Q043GygN0