TambarLab

Our lab discussed the career of Alison Narayan @AlisonNarayanUM. What’s your favorite paper from @NarayanLab? pubs.acs.org/doi/10.1021/ja… nature.com/articles/nchem… doi.org/10.1021/acs.an… dx.doi.org/10.1021/acs.ac… doi.org/10.1021/jacs.3… doi.org/10.1021/acs.jp… doi.org/10.1039/c1ob06…

It was great hosting Dr. Stephen Starnes and the REU students from East Texas A&M University @etamuniversity! We had a fun day talking about the Drug Discovery process with young scientists. Thank you Dr. Arnaldo Díaz @ADiaz_PhD for sponsoring the event. See you all next year!

Check out this formal [3+3] annulation developed by Movassaghi to assemble the CDE-ring system of himandrine.

Stoltz completed an elegant synthesis of ineleganolide (pun intented) with this cascade sequence to furnish the pentacyclic core. @thestoltzgroup

Check out this elegant cascade sequence reported by Ang Li for the asymmetric total synthesis of arcutinidine, arcutinine, and arcutine.

Check out this elegant tandem cascade en route to the total synthesis of (+)-Lycoflexine, which was reported by Jürgen Ramharter and co-workers.

Check out this elegant benzyne-mediated tandem reaction for the rapid assembly of nitrogen heterocycles, which was reported by Richard Hsung. Do you know the mechanism?

Our lab recently discussed the research career of Andrew Myers. What’s your favorite paper from the Myers Lab? Here are some papers selected by us: pubs.acs.org/doi/10.1021/ja… science.org/doi/10.1126/sc… pubs.acs.org/doi/10.1021/ac… nature.com/articles/nchem… pubs.acs.org/doi/10.1021/ac…

Our lab recently discussed the career of our Eric Jacobsen @JacobsenLab. What’s your favorite paper from Jacobsen? Here are some papers selected by us: nature.com/articles/s4158… pubs.acs.org/doi/10.1021/ja… pubs.acs.org/doi/10.1021/ja… pubs.acs.org/doi/10.1021/ac… pubs.acs.org/doi/10.1021/ja…

Our lab recently discussed the career of our good friend Mingji Dai @MingjiDai. What’s your favorite paper from the Dai Lab? Here are some papers selected by us: pubs.acs.org/doi/10.1021/ja… onlinelibrary.wiley.com/doi/10.1002/an… pubs.acs.org/doi/10.1021/ja… pubs.acs.org/doi/10.1021/ja…

Our lab recently discussed the career of our good friend David Nagib @nagiblab. What’s your favorite paper from Nagib? Here are some papers selected by us: pubs.acs.org/doi/10.1021/ja… nature.com/articles/natur… pubs.acs.org/doi/10.1021/ja… pubs.rsc.org/en/content/art…

Our lab recently discussed the research career of Veronique Gouverneur. What’s your favorite paper from the Gouverneur Lab? Here are some papers selected by us: doi.org/10.1021/jacs.3… science.org/doi/10.1126/sc… pubs.rsc.org/en/content/art… science.org/doi/10.1126/sc…

We’re hiring a biology postdoc in the Tambar Lab at UT Southwestern! Interested in chemical biology, protein-small molecule interactions, target engagement, and targeted protein degradation? We’d love to hear from you. PhD required. @utswpda Apply here: apply.interfolio.com/187301

Our work on direct and redox-neutral C–H functionalization of pyridines with nucleophiles @J_A_C_S @ACSPublications Congratulations @BARALNILOFAR #NPDF @Pinku_Saikia25 @Devendr57748399 and Sabir pubs.acs.org/doi/10.1021/ja…

Our lab recently discussed the research career of our good friend Neil Garg @GargLab @uclachem @UCLA. What’s your favorite paper from the Garg Lab? Here are some papers selected by us: pubs.acs.org/doi/10.1021/ja… pubs.acs.org/doi/full/10.10… nature.com/articles/nchem…

Check out this cool cascade oxidative trifluorination and halogenative cyclization of tryptamine-derived isocyanides, which was recently reported by Honggen Wang and Qingjiang Li. Do you know the mechanism?

Check out our review in @JournalCancer on recent advances in targeting HIF‐2 in renal cell carcinoma, with a focus on belzutifan. Academic labs can have a tangible impact on the treatment of cancer patients. @AmericanCancer @utswcancer @UTSWMedCenter acsjournals.onlinelibrary.wiley.com/doi/10.1002/cn…

Check out our recent paper in @ChemCatalysis on the photocatalytic three-component carbonyl alkylative amination. This reaction couples aldehydes, anilines, and alkyl arenes via direct C–H functionalization. cell.com/chem-catalysis…

Happy Holidays and Happy New Year from the Tambar Lab! Enjoy our Famous Chemists of the Week from 2025!

Happy Holidays and Happy New Year from the Tambar Lab! Enjoy our Mechanism Problems from 2025!