Tayla Rees

We're thrilled to announce that we have recently funded a new research project. This project will see a new partnership with King's College London & provide a unique opportunity to better understand the early signs of an attack & how it can be prevented. migrainetrust.org/news/new-resea…

Excellent paper by @zoe_tasma studying the pharmacology and expression of PACAP and VIP receptors in the rat spinal cord out in BJP. The study identifies that the PAC1 receptor is likely the major subtype present to mediate PACAP's nociceptive actions. bpspubs.onlinelibrary.wiley.com/doi/full/10.11…

Cryo-EM Structure of the Human Amylin 1 Receptor in Complex with CGRP and Gs Protein | Biochemistry pubs.acs.org/doi/10.1021/ac… Our latest paper. Great work from @ChemJ_Tsao @bluesocks81 and team @CCeMMP . Funding by @arc_gov_au and @nhmrc

So happy this paper with the amazing @zoe_tasma, @MGarelja, @Dr_ChristopherW, and @debbie_hay is out. Amylin, CGRP, and the amylin receptor subunit, CTR, are expressed in the C1/2 cervical DRG. Could they potentially contribute to migraine? …alofheadacheandpain.biomedcentral.com/articles/10.11…

Very happy to have my recent work on "Time-resolved cryo-EM of G protein activation by a GPCR" out in Nature today! #cryoEM #GPCR @Nature #LabSkiniotis nature.com/articles/s4158…

This March, @KingsCollegeLon scientist Dr Philip Holland, will be swapping his lab coat 👨‍🔬 for his running shoes 🏃‍♂️ and running 100 miles to raise funds for The Migraine Trust! You can follow Philip’s progress, and support his fundraising page here: buff.ly/3Il0cpf

PainFace paper is out! This software can be used to quantify facial grimaces indicative of spontaneous pain in mice. Give it a try! Currently has over 280 registered users who performed >27 million grimace evaluations. journals.lww.com/pain/fulltext/…

20-30% of scientists may be using commercial antibodies that don’t work as advertised in their protein studies, potentially skewing results. elifesciences.org/digests/91645/….

@O_Grech @BrainLabBhamUk @daniel_j_fulton @IMSR_UoB @unibirm_MDS Congratulations 🥳

@debbie_hay opens this mornings Scientific Session 4 on Biomarkers and pathophysiology in migraine discussing peptides as biomarkers #EHC2023

Had a great time hearing the amazing talks and presenting my ePoster at #EHC2023

A rose by any other name, or the continuing story of the AMY1 receptor as a potential mediator of CGRP in migraine pubmed.ncbi.nlm.nih.gov/37580864/

Calcitonin/PAC1 receptor splice variants: a blind spot in migraine research cell.com/trends/pharmac…

Amalina from UNSW, Australia received the best poster award selected by Junior Group during International Headache Conference @UNSW #ihc2023 #headache Thanks @ppozorosich for Thr amazing video. @AusNZHeadSoc @HeadacheAus @ihs_official

Excellent talk by @alejandro_labas at the @ihs_official Fellowship session 👏👏👏👏 @JanH_Headache @HeadacheKCL @WolfsonCARD #IHC2023

@ALPHACGRP giving a talk at #ihc2023 about what comes after CGRP in migraine! @UIowaNeuro @UIowa_PAIN

Come to my poster (DP-020) at #IHC2023! CGRP-responsive receptors in migraine relevant zones, and RNA vs Protein expression 🤜💥🤛. I have nice pictures, love GPCRs, and have many hand gestures. So many thanks to @NeurologicalNZ for helping me get here!

This review focuses on summarizing the general pharmacology of the different types of GCRP-related treatments currently available. Latest evidence and non-responding is also adressed. Open access: rdcu.be/dl0DV #migraine #headache #neurology

Interested in amylin, CGRP and amylin receptors? Presenting my poster on their expression in sensory ganglia on Friday the 15th #IHC2023

Beautiful and fun start to #IHC2023 in Seoul