TeufelLab

Two new studies lead by Sven Sowa: We developed a bioinformatic tool for the rapid analysis of related biosynthetic gene clusters to streamline the discovery of novel natural product congeners and distinct tailoring enzymes pubs.acs.org/doi/10.1021/ac… pubs.acs.org/doi/10.1021/ac…

Check out our new study lead by Heiner Weddeling! We explored amide bond synthetases to bioengineer new-to-nature rubromycin polyketides including “Trojan horse” siderophore conjugates. pubs.acs.org/doi/full/10.10…

We have positions opening in September 2026: -Postdoc in Structural Biology -PhD in Natural Product Biosynthesis & Bioengineering Join us in Basel – great colleagues, competitive salary, and an outstanding pharma & biotech ecosystem. Interested? Please rt (links below)!

New study in @JACS overturns the proposed Baeyer-Villiger Monooxygenase role of RslO9 in rishirilide biosynthesis. Instead, it uses a Hooker oxidation-like mechanism: substrate hydroxylation + alkyl migration. Led by Heiner Weddeling @unibas pubs.acs.org/doi/10.1021/ja…

YUCCA enzymes are key for plant auxin biosynthesis – but Sina Rütschlin (@Unibas) discovered their surprising dual role: they also drive chlorophyll degradation, which may link leaf senescence to auxin homeostasis in plants! Great collab w/ Simone Moser onlinelibrary.wiley.com/doi/10.1002/an…

We are organizing our second workshop in this June at Riga with four Invited Speakers, Yvain Nicolet, Robin Teufel, Joleen Masschelein and Florian Hubrich.

We had a wonderful 3rd Japanese-German Symposium on the Biosynthesis of Natural Products in Bonn. Thank you all for the great talks and fruitful discussions! See you again at the next conference in Japan.

Very happy that our work on understanding tropolone biosynthesis is now out in @mbiojournal Great work from the PhD of @AlasterMoffat and some excellent biochemistry from @TeufelLab #biosynthesis #Pseudomonas journals.asm.org/doi/10.1128/mb…

Happy to share our latest publication on a #flavin #oxidase family and a tool to depict and simplify enzyme mining and selection by @DEggerichs et al #biocatalysis #flavoprotein #enzymology #biotechnology nature.com/articles/s4200…

🙏 for the highlight! @ChemEurope

New @biorxiv_micrbio preprint from our group: "Understanding the biosynthesis, metabolic regulation, and anti-phytopathogen activity of 3,7-dihydroxytropolone in Pseudomonas spp.” Great work from @TheRealAlimoff with some important biochemical data from @TeufelLab

Join us! We are looking for a new team member (PhD student) with strong background in organic chemistry. Organic chemistry meets #DirectedEvolution Highly interdisciplinary & passionate research group 🙏RETWEET (We want to recruit internationally) uni-bielefeld.hr4you.org/job/view/3249/…

We have set up a new Masters degree program, the MSc Physics of Life, at the Biozentrum in Basel. I am looking forward to training the next gen avant-garde at the interface of physics, maths, engineering and biology! 👉Scholarships available👈

The Berg Lab is hiring two postdocs for the @ERC_Research funded Synergy project “Archean Park” (duration 3 years). #biochemistry, #microbiology Link to application: tinyurl.com/arnmw9p3 Please RT!

I have one open Postdoc position (100%, natural product biosynthesis, protein biochemistry) & one PhD position (100%, natural products against glioblastoma brain cancer). Join our lab with great colleagues and salaries located in vibrant Basel. Please RT! jobs.unibas.ch/?lang=en

still some time to apply ;) jobs.unibas.ch/offene-stellen…

I have an open 100% postdoc position (natural products & mass spectrometry / ms networking). Come and work with us in fantastic Basel with great colleagues / salary and a vibrant pharma community ;). Please RT! jobs.unibas.ch/offene-stellen…

Curious about our group? Visit our website to find the latest News and Publications, and get to know the team! Also, check out the complete lecture "Organic Chemistry for Biologists" by @TBoettcher_Lab boettcher-lab.univie.ac.at