TexMachina

@CuriosityonX Haley's comet was already breaking apart on the last orbit. It's possible it won't even return in 2061.

How old will you be when the Halley's comet visits Earth's sky again in 2061? I'll be 66!

@AntiWokeMemes Those overpriced dinosaur chicken nuggets and macaroni and cheese you see at the back of EVERY DAMN MENU is what you get with that soft parenting bullshit.

Parents on the internet are arguing about this... What are your thoughts?

@ZinCraig @AVGirl4Life You do it for other women who criticize each other for wearing the same top twice in a month. Maybe try not caring what the other women think.

@AVGirl4Life They tell us all the time "I prefer you without make-up" but what they don't understand is that we don't do if for them, we do it for us!

True or False?

@its_The_Dr There's no way in hell Sergio said that.

One of the Greatest Spaghetti Western Scenes.

@VideosIrish Look what they did to my boy.

Back story on the incident in belfast where an african immigrant tried to behead a native

@lil_doza Hard to believe Tommy Robinson tried to cot off that man's head.

I’m getting reports the black fella might be dead. If this is true, Tommy Robinson and every other racist cunt who whipped up these scum should be held accountable.

@zarahussain999 "The far right"🙄 Not wanting your own country to be invaded by hostile foreigners is FAR RIGHT.

The far right in Belfast are attacking homes that belong to black and brown people including families. Children are living in fear as they attack with bricks, sticks and other objects. Where’s the police? Keir Starmer and Shabana Mahmood. - WE FEEL UNSAFE

@SenRickScott I had planned to start Social Security at 62 because I feared this was going to happen but it may not be soon enough.

Is everyone paying attention? We have just SIX YEARS before Social Security is insolvent. Congress needs to stop burning money on fraud and crappy programs, balance the budget, and PROTECT Social Security so we can keep our promises to American seniors.

@coastpooplitics @TheGhostReport @DyingHostThe2nd No loss there.

@TheGhostReport Images by @DyingHostThe2nd

-----------Ghost Show Meme Post------------ Post your funniest Ghost Show AI or other spicy memes here. I'll air the best ones on tonight's Ghost Show. Note: Anyone who posts more than 2 times will be ignored because you're wasting the show's time! #GhostShow #Memes

@DefiantLs This absolutism that they are the good guy is why they are all ok with their side cheating.

John C. Reilly on politics: "It’s pretty obvious who’s on the side of humans"

@fiago7 Post Modernism was a mistake

That‘s a lovely little metal ball 👍

@OwenGregorian Why is every post a wall of text now? Did they do something to the algorithm to make all of the AI article writing programs switch over to this obnoxiously huge format? Just give me a bullet list.

Scientists discover how coffee interacts with the gut microbiome to affect the human brain | Eric W Dolan, PsyPost Regularly drinking coffee tends to modify the bacteria living in the human digestive system, which in turn influences a person’s mood, memory, and physical health, according to a new study. The research provides evidence that both caffeinated and decaffeinated coffee offer distinct benefits for psychological well-being and bodily functions. These findings were published in the journal Nature Communications. Coffee is a complex beverage made up of many plant-based compounds, including caffeine and polyphenols. Polyphenols are naturally occurring plant chemicals known for their antioxidant properties. A growing body of evidence suggests that the bacteria living in the human gut respond to the compounds found in coffee. John Cryan, professor and chair of the Department of Anatomy and Neuroscience at University College Cork in Ireland, led the research team. “This study builds on our long-standing interest in how diet interacts with the gut microbiome to influence brain function, the so-called microbiota-gut-brain axis,” Cryan said. “Coffee is one of the most widely consumed beverages in the world and one of the richest sources of dietary polyphenols, yet most research has focused almost exclusively on caffeine. We wanted to understand how coffee as a whole influences the microbiome, metabolism, mood, cognition, and physiology.” The human digestive system is home to trillions of microorganisms, collectively known as the gut microbiome. These microbes communicate continuously with the brain through a network called the microbiota-gut-brain axis. This two-way communication pathway helps regulate digestion, immune responses, and even mood. “It is also worth noting that a growing body of epidemiological research links moderate coffee consumption with healthier aging and a reduced risk of neurodegenerative disorders such as dementia and Parkinson’s disease,” Cryan explained. “Our findings do not prove that coffee prevents these conditions, but they do provide possible biological mechanisms through the gut microbiome and metabolism that may help explain some of those associations.” The researchers aimed to explore how the timing of coffee habits affects mood and cognition through the lens of the gut microbiome. They recruited 62 healthy adults living in Ireland, ranging in age from 30 to 50 years old. Half of the participants were moderate coffee drinkers, meaning they typically drank three to five cups per day, while the other 31 participants were non-coffee drinkers. The scientists compared both groups at the beginning of the study. Participants completed psychological questionnaires to assess stress, impulsivity, and sleep quality. They also provided blood, saliva, urine, and stool samples. To ensure diet was not causing differences, participants kept detailed daily food logs. Following this initial assessment, the non-coffee drinkers concluded their participation. The habitual coffee drinkers were instructed to stop drinking any type of coffee or caffeinated beverage for two weeks. This abstinence period allowed the scientists to observe how the body and gut microbiome reacted to the sudden absence of coffee. After the two-week withdrawal phase, the coffee drinkers returned for a second round of tests and sample collections. They were then randomly divided into two groups. For the next three weeks, 16 participants drank four daily cups of caffeinated instant coffee, while the other 15 participants drank four daily cups of decaffeinated instant coffee. At the end of this three-week reintroduction phase, the participants completed the final round of questionnaires, cognitive tests, and biological sampling. The cognitive tests included memory tasks and an emotional recognition task. The scientists also induced a mild stress response by having participants hold their hand in ice-cold water while being recorded. When comparing the groups at the beginning of the study, the authors noted that regular coffee drinkers scored higher on measures of impulsivity and emotional reactivity than non-coffee drinkers. During the two-week withdrawal period, these elevated levels of impulsivity and emotional reactivity dropped. The stress testing revealed that baseline stress hormones and physical stress resilience were essentially the same for both regular coffee consumers and those who never drank it. Upon reintroducing coffee, both the caffeinated and decaffeinated groups reported lower levels of perceived stress and fewer symptoms of depression. The caffeinated coffee group experienced unique psychological benefits, reporting reduced anxiety and decreased psychological distress. The caffeinated group also showed lower levels of certain inflammatory proteins in their blood after drinking the coffee for three weeks. Participants who drank decaffeinated coffee showed improvements in sleep quality and engaged in more physical activity. The decaffeinated group also demonstrated enhanced performance on memory tests. “One of the biggest surprises was that decaffeinated coffee produced many of the same effects as regular coffee,” Cryan noted. “That suggests caffeine is only part of the story, and that other coffee compounds, particularly polyphenols, may play a major role in shaping the gut-brain axis. We were also struck by how rapidly the microbiome responded to changes in coffee intake. The system appears to be highly dynamic and sensitive to dietary inputs.” “The main takeaway is that coffee is much more biologically complex than we tend to think,” Cryan said. “It is not simply a stimulant; it appears to interact with the gut microbiome, immune system, metabolism, and brain simultaneously. Our findings suggest that both caffeinated and decaffeinated coffee can influence stress, mood, and cognition, likely through mechanisms involving the gut microbiome and microbial metabolites.” The stool samples revealed that regular coffee drinkers hosted a different composition of gut bacteria compared to non-coffee drinkers. Specifically, coffee drinkers had higher levels of several bacterial strains, such as Cryptobacterium curtum and Eggerthella. Stopping and restarting coffee intake caused shifts in these specific bacterial populations, but it did not change the overall diversity of the gut microbiome. Analysis of the participants’ urine showed changes in compounds related to the breakdown of caffeine and polyphenols. Interestingly, there was a high degree of variation in how individuals processed polyphenols. The authors linked this variation to differences in each person’s specific gut bacteria. “This was a controlled experimental study in 62 healthy adults, so the findings should not be interpreted as evidence that coffee dramatically changes personality or cognition,” Cryan warned. “The effects were subtle but measurable, and are probably most meaningful in terms of understanding how habitual dietary exposures shape physiology over time. The study is perhaps more important mechanistically, showing that everyday dietary components can influence the microbiome and brain together, than as a basis for immediate lifestyle recommendations.” “This was a relatively modest-sized study in healthy participants, and we are observing associations and physiological responses rather than diagnosing clinical effects,” Cryan said. “We also cannot conclude that coffee is universally ‘good’ or ‘bad’ for cognition or mood. However, as a frequent coffee drinker, I am reassured that there may be positive consequences of my habit.” “Another important point is individual variability,” he added. “Responses to coffee likely depend on a variety of factors including genetics, sleep, baseline microbiome composition, habitual caffeine intake, and broader dietary patterns.” “I think one of the broader messages is that the gut microbiome is not a static system,” Cryan explained. “It responds continuously to what we eat and drink, and those microbial changes may have consequences far beyond digestion, including for mood, stress resilience, and cognition.” “We are very interested in understanding how specific dietary components, especially polyphenols, interact with the microbiome to influence mental health and brain function,” Cryan said regarding next steps. “Future work will explore whether individual microbiome profiles can predict different responses to coffee and whether these interactions may eventually support more personalized nutritional strategies. We are particularly interested in how dietary components can affect brain health via the microbiome. Thus much more large-scale longitudinal studies are needed.” Read more: psypost.org/scientists-dis…

@Samzmarvel How many more of these crap movies are they going to make before they realize people are just over the comic book genre. Especially since they warped it into their narrative abandoning all traditional archetypes.

Bob went down. Sentry woke up. one of the coolest moments in the MCU

@Kachidey4you The reason his helmet opened all the way is because Robert Downey Jr's contract specified that he had to have a certain amount of face time on screen which is also why they developed the floating Tony head surrounded by computer graphics for when the helmets closed.

Fatal flaws in Iron Man’s Helmet, many people fail to notice

@TheCalvinCooli1 Isn't leaving the space by faith blank the same as atheist?

🚨Report: The Department of War has officially slashed its list of recognized military religious faiths from 211 to 31, removing approximately 180 belief systems. The eliminated designations include atheism, paganism, Wicca, humanism, and Unitarian Universalism.

@defense_civil25 How many Chinese yuan fund your campaign?

I demand a halt to all new data centers statewide! If data centers need to be cooled, build them in the arctic. Or place them on the coast and use sea water!!

@Crazyunfill94 Livestream it.

🇯🇵 Japan has ordered the demolition of the illegal mosque inaugurated by the Pakistani Ambassador! The bulldozer is now set to roll on this mosque that was built without any permits. Japan is taking strong action against illegal Islamic constructions and infiltration.

@BlackAndNative1 I agree with how the boycott is absurd and racist but it was a Chinese virus from the Wuhan viral lab. Nobody can deny that now.

SO NOW ASIANS ARE SAYING IT’S A HATE CRIME TO NOT DO BUSINESS WITH THEM?‼️🤔 How does that work?‼️🤔 And how are you not a monolith if you call all melanated people in America Black Americans, does that make us a monolith?‼️🤔

@TahraHoops You know the Democrats are cheating and you are OK with it because you think they are the good guys.

if this is hard for you to understand maybe you should not be in charge of a 15 billion dollar city budget