Sam Reynolds

we don't have nearly enough prediction markets on clinical trials and it's a goldmine sitting in plain sight martin shkreli claims he made over $100M shorting pharma his edge wasn't insider info, it was reading publicly available clinical trial data that nobody else bothered to look at every FDA filing, every interim result, every adverse event report, every endpoint analysis were all public a pharmacist who reads the molecular data has more edge on these outcomes than any wall street analyst running a DCF model. this is one of the few areas where domain expertise destroys financial expertise and there's almost no prediction market infrastructure built for it whoever builds deep clinical trial prediction markets unlocks something powerful where the market itself becomes the information product you're broadcasting what the most informed people in the world actually think about the science the opportunity is wide open

Big layoffs at StarkWare as it reorganizes, with @EliBenSasson telling staff in a town hall it’s elevating its quantum-safe bitcoin researcher to run a new applications unit amid falling layer-2 revenue

just a reminder that the bitcoin mempool is empty

@FattyNatsu Absolutely can in HK.

Can you swap crypto to cash without KYC where you live?

HKD stablecoin announcement coming today. HKMA holding a 5pm technical briefing and press conference with licensed stablecoin issuers.

@Kiefer_Wool @howardanglin That would make a top tier liquor cabinet

An example of how cheap great quality antique furniture is now. This George III mahogany secretaire bookcase originally sold in the 1980s for £29,000, this just sold on the 2nd of April for £400 at auction.

Judas Iscariot was paid 30 pieces of silver for turning Jesus Christ in to the Roman authorities. But he made nearly 10 times that amount by placing a Polymarket bet accurately predicting the day of Christ’s death.

Chinese car manufacturers should only be allowed to sell into the US as part of joint ventures in which they hold a minority stake and should be required to transfer all technology they use in production of the car to their joint venture partner.

@jukan05 Try Neihu. Otherwise anywhere along the blue line works. Public transit in Taipei is excellent.

I just booked my hotel and flight for Computex Taipei… Hotels close to the Nangang Exhibition Center were really expensive.

HKD stablecoin has missed its March launch date with no licenses issued. coindesk.com/policy/2026/04…

@Langerius I did my time in the trenches of Gigabyte's motherboard division at their Taipei HQ. Know full well how little money they make.

@thesamreynolds Consumer hardware is margin hell enterprise prints

Asus says the low-end Macbook Neo is a 'shock'. But the stock is performing very well this morning in Taiwan which shows how little profit notebooks have versus enterprise/servers. pcmag.com/news/asus-co-c…

Congratulations @NDP. Before this you'd probably struggle to find an American that had heard of your party.

@Chris_arnade @3RenChengHu Then go on Polymarket's discord and propose a market

@3RenChengHu Again. I’m willing to bet!

Being here in Korea, listening to everyone talk about it as the canary in the coalmine of declining global birthrates, and the end of a culture, I'm willing to bet that sometime within next twenty years this place will turn on a dime and there will be a baby boom. Not having kids is a current fad, and like all fads, it will fade and be replaced by a counter-fad. And nobody does fads with such intensity, and volatility, as the Koreans.

@alreadydawn Looks quite decent. The campuses of most Taiwanese universities are quite dilapidated by comparison.

Tsinghua University students eat like KINGS 🧵 Today I had the pleasure of touring and eating at a cafetaria at Tsinghua University, China's number one college in Beijing. This one, Zijingyuan (紫荊園), is loaded to the gills with different stalls at each of its 4 floors. It is one of \\20// cafetarias serving Tsinghua's 63k students and 17k staff. As usual, the scale in China is simply nuts. Each of the stall among the 4 floors is unique. Most of the various Chinese cuisines (think Shanghai food, Sichuan food, Hunan food) are represented here - from sauerkraut fish and HK BBQ to soup dumplings and a gajillion different stir-fries. Taiwanese/Fujian food was missing though. Sad 🥲 The pricing is decently affordable too, at about 5 USD per meal if you want to have hearty portions of protein. The school subsidizes.. in other words, the CPC subsidizes. Contrast this to American universities that serve straight garbage for 20 dollars each meal. That is what happens when international finance takes over your country, by the way - every single thing becomes usury, every single time.

I think we’re going to look back at the 90s and realize it was the best era of tech for humanity. Computers were starting to make things more efficient, but smartphones didn’t exist yet, so work didn’t follow you home. No social media, no constant news cycle. When work was over, you were actually done.

@JAN3com Exists in Canada: cbsa-asfc.gc.ca/travel-voyage/… US: cbp.gov/travel/cbp-sea… Anywhere in the world you have limited rights at the border. In Hong Kong they are pretty adament to point out that inland police need a warrant to access electronic devices hongkongfp.com/2026/03/26/fal…

Hong Kong just made refusing to hand over your Bitcoin wallet a criminal offense. ‼️ The updated National Security Law took effect on March 23. It forces everyone on Hong Kong soil, including tourists and transit passengers, to provide passwords and decryption assistance to police on demand, with no exceptions for personal devices. This is the kind of law that might sound far-fetched until they introduce one where you live.

Whoa this is awesome. This SEO case study tested what would happen by producing purely AI content on 20 domains. Growth soared in the first two months and then completely collapsed by month 3:

@isaacstonefish @erinhale Guess what every border force in the world can do cbsa-asfc.gc.ca/travel-voyage/…

Why not to bring your work or personal cellphone to Hong Kong, reason #4552.

Governance tokens are dead 💀 Have been down only, no matter the market Most governance systems don't work, and most protocols don’t even need it The only way forward is utility, equity-like exposure, revenue share - that’s the next token meta