TutorMD

Rheumatoid Arthritis✅📍 Rheumatoid Arthritis (RA) is a chronic, systemic autoimmune disease characterized primarily by inflammatory arthritis affecting the synovial joints. 🔸Keys: Symmetric Polyarthritis, Morning Stiffness, Extra-articular manifestations #MedX #Rheumatology

Penicillins Summary💊📍 #medtwitter #foamed #Meded Via- @ManualOMedicine

Sites of action of diuretics along the nephron. bjaed.org/cms/10.1016/j.…

Protein Synthesis Inhibitors ✅📝 Via @PharmaFactz

Approach to Thrombocytopenia and Platelet Transfusion 📝✅ Thrombocytopenia (TP) is a localization problem. In anemia, the early signal is often MCV + retics. In TP, the early signal is often clinical context, which then guides mechanistic localization. Via- @WilliamAird4

Inflammatory markers

The Taxonomy of Medical Research:📒 Understanding where evidence comes from is the first step in critical appraisal. Whether you are a student, resident, or seasoned clinician, this taxonomy is your roadmap through the medical literature. #MedEd #MedicalResearch #TutorMD

Parkinson vs Huntington vs Wilson Disease

⚡10 ECG patterns where missing the diagnosis can be catastrophic 🧠 Wellens 🔥 Brugada ⚡ Hyperkalemia 🫁 Massive PE ❤️ STEMI 🚨 Left main /proximal LAD ischemia 💥 Ventricular tachycardia 🔄 Torsades de pointes 🧊 Complete heart block 💧 Cardiac tamponade via @Rheumat_Aravind

Tuberculosis Treatment Guidelines

Decorticate vs Decerebrate – 30-sec Neuro Pearl 🧠 Mnemonics • Decorticate = “CORE” → arms flexed to chest • Decerebrate = “STRAIGHT” → arms extended ⚠️ Decorticate → Decerebrate = worsening / descending herniation (emergency) #Neurology #MedEd #NeuroExam #Doctors

Cranial Nerves 🧠📍

💥 Oncogenes, Tumor Suppressors & Step 1 High-Yield Cancers! 🧬 4 images 🖼️ | 2-min read ⏱️ Master MUST-KNOW gene–tumor associations for USMLE Step 1 & boards 🧠🔥 #MedTwitter #Step1 #Oncology #HighYield #MedEd #MedicalStudents #FutureDoctor #BoardPrep #Pathology #CancerGenetics

@drabdulhameed07 @grok Answer this according to British Thoracic Guidelines.

Oxygen is indicated when SpO₂ < ? A. 98% B. 95% C. 92% D. 90%

@simplify_drugs ➰ Edrophonium (Tensilon) Test – Exam Classic ⬇️ Before: Ptosis / muscle weakness ⬆️ After: Rapid, transient improvement 💥 🧬 Mechanism: • Short-acting AChE inhibitor • ↑ ACh at neuromuscular junction 🎯 Diagnostic for: Myasthenia gravis ⚠️ Cardiac side effects #MedTwitter

What’s the test called as 🤔

@mednomics 🧠💡 Classic Exam Pearl: The triad Dermatitis + Diarrhea + Dementia = PELLAGRA 🧬 Deficient nutrient: Niacin (Vitamin B3) 🔁 Can also result from tryptophan deficiency (niacin precursor) ⚠️ 4th “D” = Death (if untreated) #MedTwitter #Step1 #Biochemistry #HighYield #USMLE

What is deficient and 4th D 🤔

@simplify_drugs Drugs that END with “-statin” but are NOT lipid-lowering statins 📌 1️⃣Somatostatin: Peptide hormone 2️⃣Nystatin: Polyene antifungal 3️⃣Cilastatin: Dehydropeptidase-I inhibitor 4️⃣Pentostatin: Antineoplastic (purine analog)

For example 🤔

@IhabFathiSulima Osteosarcoma 🦴

What is the diagnosis?

Lyme disease is the most common vector-borne illness in the United States. It is caused by the gram-negative spirochete, 𝘉𝘰𝘳𝘳𝘦𝘭𝘪𝘢 𝘣𝘶𝘳𝘨𝘥𝘰𝘳𝘧𝘦𝘳𝘪 𝘴𝘦𝘯𝘴𝘶 𝘴𝘵𝘳𝘪𝘤𝘵𝘰. 𝘉. 𝘣𝘶𝘳𝘨𝘥𝘰𝘳𝘧𝘦𝘳 is transmitted by species of Ixodes tick (e.g., deer ticks or black-legged ticks). The range of this vector and the length of the season during which it is active have increased with climate change. Learn more about Lyme disease and test your diagnostic and therapeutic skills in a new Interactive Medical Case: nej.md/4qkJFWl

🧬Only ~1–2% of human DNA is protein-coding(exons) 📌 Remaining ~98%👇: • Introns • Regulatory DNA (promoters, enhancers, silencers) • Non-coding RNAs (miRNA, lncRNA) • Structural regions (telomeres, centromeres) 📌Disease often results from regulatory or epigenetic defects.

🧬 Human Genome Project (HGP)– • Completed in 2003 • Only ~1–2% of DNA is protein-coding (exons) • Remaining DNA = introns, regulatory elements, ncRNA • Euchromatin = active | Heterochromatin = inactive • mtDNA: 16.6 kb, 37 genes, maternal inheritance #MedicalEducation #DNA

🧬 Human DNA • Human haploid genome ≈ 3.2 billion base pairs • Diploid cell ≈ 6.4 billion bp • Organized into 23 chromosome pairs (46 total) • Humans have only ~20,000–21,000 protein-coding genes 📌 Gene number ≠ complexity → regulation matters #USMLE #Step1 #Genetics